ID A0A0R4J082_MOUSE Unreviewed; 520 AA. AC A0A0R4J082; DT 20-JAN-2016, integrated into UniProtKB/TrEMBL. DT 20-JAN-2016, sequence version 1. DT 31-JUL-2019, entry version 25. DE SubName: Full=Cyclic AMP-responsive element-binding protein 3-like protein 1 {ECO:0000313|Ensembl:ENSMUSP00000028663}; DE SubName: Full=cAMP responsive element binding protein 3-like 1, isoform CRA_b {ECO:0000313|EMBL:EDL27588.1}; GN Name=Creb3l1 {ECO:0000313|EMBL:EDL27588.1, GN ECO:0000313|Ensembl:ENSMUSP00000028663, ECO:0000313|MGI:MGI:1347062}; GN ORFNames=mCG_16131 {ECO:0000313|EMBL:EDL27588.1}; OS Mus musculus (Mouse). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; OC Muroidea; Muridae; Murinae; Mus; Mus. OX NCBI_TaxID=10090 {ECO:0000313|Ensembl:ENSMUSP00000028663, ECO:0000313|Proteomes:UP000000589}; RN [1] {ECO:0000313|EMBL:EDL27588.1} RP NUCLEOTIDE SEQUENCE. RC STRAIN=Mixed {ECO:0000313|EMBL:EDL27588.1}; RX PubMed=12040188; DOI=10.1126/science.1069193; RA Mural R.J., Adams M.D., Myers E.W., Smith H.O., Miklos G.L., Wides R., RA Halpern A., Li P.W., Sutton G.G., Nadeau J., Salzberg S.L., Holt R.A., RA Kodira C.D., Lu F., Chen L., Deng Z., Evangelista C.C., Gan W., RA Heiman T.J., Li J., Li Z., Merkulov G.V., Milshina N.V., Naik A.K., RA Qi R., Shue B.C., Wang A., Wang J., Wang X., Yan X., Ye J., RA Yooseph S., Zhao Q., Zheng L., Zhu S.C., Biddick K., Bolanos R., RA Delcher A.L., Dew I.M., Fasulo D., Flanigan M.J., Huson D.H., RA Kravitz S.A., Miller J.R., Mobarry C.M., Reinert K., Remington K.A., RA Zhang Q., Zheng X.H., Nusskern D.R., Lai Z., Lei Y., Zhong W., Yao A., RA Guan P., Ji R.R., Gu Z., Wang Z.Y., Zhong F., Xiao C., Chiang C.C., RA Yandell M., Wortman J.R., Amanatides P.G., Hladun S.L., Pratts E.C., RA Johnson J.E., Dodson K.L., Woodford K.J., Evans C.A., Gropman B., RA Rusch D.B., Venter E., Wang M., Smith T.J., Houck J.T., Tompkins D.E., RA Haynes C., Jacob D., Chin S.H., Allen D.R., Dahlke C.E., Sanders R., RA Li K., Liu X., Levitsky A.A., Majoros W.H., Chen Q., Xia A.C., RA Lopez J.R., Donnelly M.T., Newman M.H., Glodek A., Kraft C.L., RA Nodell M., Ali F., An H.J., Baldwin-Pitts D., Beeson K.Y., Cai S., RA Carnes M., Carver A., Caulk P.M., Center A., Chen Y.H., Cheng M.L., RA Coyne M.D., Crowder M., Danaher S., Davenport L.B., Desilets R., RA Dietz S.M., Doup L., Dullaghan P., Ferriera S., Fosler C.R., RA Gire H.C., Gluecksmann A., Gocayne J.D., Gray J., Hart B., Haynes J., RA Hoover J., Howland T., Ibegwam C., Jalali M., Johns D., Kline L., RA Ma D.S., MacCawley S., Magoon A., Mann F., May D., McIntosh T.C., RA Mehta S., Moy L., Moy M.C., Murphy B.J., Murphy S.D., Nelson K.A., RA Nuri Z., Parker K.A., Prudhomme A.C., Puri V.N., Qureshi H., RA Raley J.C., Reardon M.S., Regier M.A., Rogers Y.H., Romblad D.L., RA Schutz J., Scott J.L., Scott R., Sitter C.D., Smallwood M., RA Sprague A.C., Stewart E., Strong R.V., Suh E., Sylvester K., RA Thomas R., Tint N.N., Tsonis C., Wang G., Wang G., Williams M.S., RA Williams S.M., Windsor S.M., Wolfe K., Wu M.M., Zaveri J., RA Chaturvedi K., Gabrielian A.E., Ke Z., Sun J., Subramanian G., RA Venter J.C., Pfannkoch C.M., Barnstead M., Stephenson L.D.; RT "A comparison of whole-genome shotgun-derived mouse chromosome 16 and RT the human genome."; RL Science 296:1661-1671(2002). RN [2] {ECO:0000313|EMBL:EDL27588.1} RP NUCLEOTIDE SEQUENCE. RC STRAIN=Mixed {ECO:0000313|EMBL:EDL27588.1}; RA Mural R.J., Adams M.D., Myers E.W., Smith H.O., Venter J.C.; RL Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases. RN [3] {ECO:0000313|Ensembl:ENSMUSP00000028663, ECO:0000313|Proteomes:UP000000589} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000028663, RC ECO:0000313|Proteomes:UP000000589}; RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112; RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., RA She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., RA Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., RA Zhou S., Teague B., Potamousis K., Churas C., Place M., Herschleb J., RA Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., RA Lindblad-Toh K., Eichler E.E., Ponting C.P.; RT "Lineage-specific biology revealed by a finished genome assembly of RT the mouse."; RL PLoS Biol. 7:E1000112-E1000112(2009). RN [4] {ECO:0000313|Ensembl:ENSMUSP00000028663} RP IDENTIFICATION. RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000028663}; RG Ensembl; RL Submitted (MAR-2016) to UniProtKB. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AL732484; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; CH466519; EDL27588.1; -; Genomic_DNA. DR RefSeq; NP_036087.2; NM_011957.2. DR Ensembl; ENSMUST00000028663; ENSMUSP00000028663; ENSMUSG00000027230. DR GeneID; 26427; -. DR KEGG; mmu:26427; -. DR CTD; 90993; -. DR MGI; MGI:1347062; Creb3l1. DR GeneTree; ENSGT00940000159848; -. DR KO; K09048; -. DR OMA; EPPDGWE; -. DR OrthoDB; 644485at2759; -. DR ChiTaRS; Creb3l1; mouse. DR Proteomes; UP000000589; Chromosome 2. DR GO; GO:0005783; C:endoplasmic reticulum; IEA:Ensembl. DR GO; GO:0016020; C:membrane; IEA:Ensembl. DR GO; GO:0000790; C:nuclear chromatin; IEA:Ensembl. DR GO; GO:0035497; F:cAMP response element binding; IEA:InterPro. DR GO; GO:0001227; F:DNA-binding transcription repressor activity, RNA polymerase II-specific; IEA:Ensembl. DR GO; GO:0046332; F:SMAD binding; IEA:Ensembl. DR GO; GO:0030968; P:endoplasmic reticulum unfolded protein response; IEA:InterPro. DR GO; GO:1902236; P:negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway; IEA:Ensembl. DR GO; GO:0040037; P:negative regulation of fibroblast growth factor receptor signaling pathway; IEA:Ensembl. DR GO; GO:1903671; P:negative regulation of sprouting angiogenesis; IEA:Ensembl. DR GO; GO:0032967; P:positive regulation of collagen biosynthetic process; IEA:Ensembl. DR GO; GO:1990440; P:positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress; IEA:Ensembl. DR InterPro; IPR004827; bZIP. DR InterPro; IPR001630; Leuzip_CREB. DR InterPro; IPR029805; OASIS. DR PANTHER; PTHR46004:SF1; PTHR46004:SF1; 1. DR Pfam; PF00170; bZIP_1; 1. DR PRINTS; PR00041; LEUZIPPRCREB. DR SMART; SM00338; BRLZ; 1. DR PROSITE; PS50217; BZIP; 1. DR PROSITE; PS00036; BZIP_BASIC; 1. PE 4: Predicted; KW Coiled coil {ECO:0000256|SAM:Coils}; KW Complete proteome {ECO:0000313|Proteomes:UP000000589}; KW Reference proteome {ECO:0000313|Proteomes:UP000000589}. FT DOMAIN 290 353 BZIP. {ECO:0000259|PROSITE:PS50217}. FT REGION 200 259 Disordered. {ECO:0000256|SAM:MobiDB- FT lite}. FT REGION 450 520 Disordered. {ECO:0000256|SAM:MobiDB- FT lite}. FT COILED 336 356 {ECO:0000256|SAM:Coils}. FT COMPBIAS 207 251 Polar. {ECO:0000256|SAM:MobiDB-lite}. FT COMPBIAS 459 490 Polyampholyte. {ECO:0000256|SAM:MobiDB- FT lite}. SQ SEQUENCE 520 AA; 57088 MW; DC2652AA1583A9F2 CRC64; MDAVLEPFPA DRLFPGSSFL DLGDLNESDF LNNAHFPEHL DHFVENMEDF SNDLFSSFFD DPVLDEKSAL LDMELDSPAP GIQAEHSYSL SGDSAPQSPL VPVKMEDTTQ DVEHGAWALG NKLCSIMVKQ EQSPELPVDP LAASSAMAAA AAMATPPLLG LSPMPRLPIP HQAPGEMTQL PVIKAEPPEM SQFLKVTPED LVQMPPTPPS SHGSDSDGSQ SPRSLPPSSP VRPMARSSTA ISTSPLLTAP HKLQGTSGPL LLTEEEKRTL IAEGYPIPTK LPLTKAEEKA LKRVRRKIKN KISAQESRRK KKEYVECLEK KVETYTSENN ELWKKVETLE TANRTLLQQL QKLQTLVTSK ISRPYKMAAT QTGTCLMVAA LCFVLVLGSL VPCLPAFSSG SMTVKEDPIA ADSVYAASQM PSRSLLFYDD GAGSWEDGRG ALLPVEPPEG WELKPGGPAE QRPQDHLRHD RADSIHETTK YLRETWPEDT DDNGTSPNFS HPKEWFHDRD LGPNTTIKLS //