ID A0A0R4J038_MOUSE Unreviewed; 661 AA. AC A0A0R4J038; DT 20-JAN-2016, integrated into UniProtKB/TrEMBL. DT 20-JAN-2016, sequence version 1. DT 11-DEC-2019, entry version 26. DE SubName: Full=Kininogen-1 {ECO:0000313|Ensembl:ENSMUSP00000023589}; GN Name=Kng1 {ECO:0000313|Ensembl:ENSMUSP00000023589, GN ECO:0000313|MGI:MGI:1097705}; OS Mus musculus (Mouse). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; OC Murinae; Mus; Mus. OX NCBI_TaxID=10090 {ECO:0000313|Ensembl:ENSMUSP00000023589, ECO:0000313|Proteomes:UP000000589}; RN [1] {ECO:0000313|Ensembl:ENSMUSP00000023589, ECO:0000313|Proteomes:UP000000589} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000023589, RC ECO:0000313|Proteomes:UP000000589}; RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112; RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., RA Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y., RA Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S., RA Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R., RA Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K., RA Eichler E.E., Ponting C.P.; RT "Lineage-specific biology revealed by a finished genome assembly of the RT mouse."; RL PLoS Biol. 7:E1000112-E1000112(2009). RN [2] {ECO:0000213|PubMed:21183079} RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]. RX PubMed=21183079; DOI=10.1016/j.cell.2010.12.001; RA Huttlin E.L., Jedrychowski M.P., Elias J.E., Goswami T., Rad R., RA Beausoleil S.A., Villen J., Haas W., Sowa M.E., Gygi S.P.; RT "A tissue-specific atlas of mouse protein phosphorylation and expression."; RL Cell 143:1174-1189(2010). RN [3] {ECO:0000313|Ensembl:ENSMUSP00000023589} RP IDENTIFICATION. RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000023589}; RG Ensembl; RL Submitted (MAR-2016) to UniProtKB. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AC154540; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR RefSeq; NP_001095881.1; NM_001102411.1. DR SMR; A0A0R4J038; -. DR jPOST; A0A0R4J038; -. DR PRIDE; A0A0R4J038; -. DR Ensembl; ENSMUST00000023589; ENSMUSP00000023589; ENSMUSG00000022875. DR GeneID; 16644; -. DR KEGG; mmu:16644; -. DR CTD; 3827; -. DR MGI; MGI:1097705; Kng1. DR GeneTree; ENSGT00950000182930; -. DR KO; K03898; -. DR OrthoDB; 740995at2759; -. DR Proteomes; UP000000589; Chromosome 16. DR ExpressionAtlas; A0A0R4J038; baseline and differential. DR GO; GO:0004869; F:cysteine-type endopeptidase inhibitor activity; IEA:InterPro. DR CDD; cd00042; CY; 3. DR InterPro; IPR000010; Cystatin_dom. DR InterPro; IPR002395; Kininogen. DR InterPro; IPR027358; Kininogen-type_cystatin_dom. DR InterPro; IPR018073; Prot_inh_cystat_CS. DR Pfam; PF00031; Cystatin; 3. DR PRINTS; PR00334; KININOGEN. DR SMART; SM00043; CY; 3. DR PROSITE; PS00287; CYSTATIN; 1. DR PROSITE; PS51647; CYSTATIN_KININOGEN; 3. PE 1: Evidence at protein level; KW Proteomics identification {ECO:0000213|MaxQB:A0A0R4J038, KW ECO:0000213|PeptideAtlas:A0A0R4J038}; KW Reference proteome {ECO:0000313|Proteomes:UP000000589}; KW Signal {ECO:0000256|SAM:SignalP}. FT SIGNAL 1..23 FT /evidence="ECO:0000256|SAM:SignalP" FT CHAIN 24..661 FT /evidence="ECO:0000256|SAM:SignalP" FT /id="PRO_5006451928" FT DOMAIN 28..131 FT /note="Cystatin kininogen-type" FT /evidence="ECO:0000259|PROSITE:PS51647" FT DOMAIN 150..253 FT /note="Cystatin kininogen-type" FT /evidence="ECO:0000259|PROSITE:PS51647" FT DOMAIN 272..375 FT /note="Cystatin kininogen-type" FT /evidence="ECO:0000259|PROSITE:PS51647" FT REGION 405..471 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT REGION 485..583 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT REGION 626..661 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COMPBIAS 406..434 FT /note="Polyampholyte" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COMPBIAS 435..469 FT /note="Basic" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COMPBIAS 496..526 FT /note="Basic" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COMPBIAS 537..583 FT /note="Polar" FT /evidence="ECO:0000256|SAM:MobiDB-lite" SQ SEQUENCE 661 AA; 73101 MW; 7744602F8DF8796E CRC64; MKLITTLLLC SGLLLTLTQG EEAQEIDCND EAVFQAVDFS LKQFNPGVKS GNQYMLHRVI EGTKTDGSPT FYSFKYLIKE GNCSAQSGLA WQDCDFKDAE EAATGECTAT VGKRENEFFI VTQTCKIAPS KAPILKAYFP CIGCVHAIST DSPDLEPVLK HSIEHFNNNT DHSHLFTLRK VKSAHRQVVA GLNFDITYTI VQTNCSKERF PSLHGDCVAL PNGDDGECRG NLFMDINNKI ANFSQSCTLY SGDDLVEALP KPCPGCPRDI PVDSPELKEV LGHSIAQLNA ENDHPFYYKI DTVKKATSQV VAGTKYVIEF IARETKCSKE SNTELAEDCE IKHLGQSLDC NANVYMRPWE NKVVPTVKCQ ALDMTEMARR PPGFSPFRSV TVQETKEGRT VSPPYIAREQ EERDAETEQG PTHGHGWLHE KQIKANKNHR GHKHGHDHGH WSPRRHGLGH GHQKPHGLGH GHQLKLDYLR HQREDGDDHT HTVGHGHGHG HGHGHGHGHG HGHGHGHGHG HGHGKHTNKD KNSVKQTTQR TESLASSSEY STTSTQMQGR TEGPTLTPPR AQPTVTSSGF QDSDFIEDVV ATTPPYDTGA HDDLIPDIHV QPDSLSFKLI SDFPEATSPK CPGRPWKPAS WKDPNTETTE FSDFDLLDAL S //