ID A0A0R4IMX2_DANRE Unreviewed; 1248 AA. AC A0A0R4IMX2; DT 20-JAN-2016, integrated into UniProtKB/TrEMBL. DT 20-JAN-2016, sequence version 1. DT 07-JUN-2017, entry version 10. DE SubName: Full=SEC24 homolog C, COPII coat complex component {ECO:0000313|Ensembl:ENSDARP00000135644}; GN Name=sec24c {ECO:0000313|Ensembl:ENSDARP00000135644, GN ECO:0000313|ZFIN:ZDB-GENE-030131-4487}; OS Danio rerio (Zebrafish) (Brachydanio rerio). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; OC Cyprinidae; Danio. OX NCBI_TaxID=7955 {ECO:0000313|Ensembl:ENSDARP00000135644, ECO:0000313|Proteomes:UP000000437}; RN [1] {ECO:0000313|Ensembl:ENSDARP00000135644, ECO:0000313|Proteomes:UP000000437} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Tuebingen {ECO:0000313|Ensembl:ENSDARP00000135644, RC ECO:0000313|Proteomes:UP000000437}; RX PubMed=23594743; DOI=10.1038/nature12111; RA Howe K., Clark M.D., Torroja C.F., Torrance J., Berthelot C., RA Muffato M., Collins J.E., Humphray S., McLaren K., Matthews L., RA McLaren S., Sealy I., Caccamo M., Churcher C., Scott C., Barrett J.C., RA Koch R., Rauch G.J., White S., Chow W., Kilian B., Quintais L.T., RA Guerra-Assuncao J.A., Zhou Y., Gu Y., Yen J., Vogel J.H., Eyre T., RA Redmond S., Banerjee R., Chi J., Fu B., Langley E., Maguire S.F., RA Laird G.K., Lloyd D., Kenyon E., Donaldson S., Sehra H., RA Almeida-King J., Loveland J., Trevanion S., Jones M., Quail M., RA Willey D., Hunt A., Burton J., Sims S., McLay K., Plumb B., Davis J., RA Clee C., Oliver K., Clark R., Riddle C., Elliot D., Threadgold G., RA Harden G., Ware D., Begum S., Mortimore B., Kerry G., Heath P., RA Phillimore B., Tracey A., Corby N., Dunn M., Johnson C., Wood J., RA Clark S., Pelan S., Griffiths G., Smith M., Glithero R., Howden P., RA Barker N., Lloyd C., Stevens C., Harley J., Holt K., Panagiotidis G., RA Lovell J., Beasley H., Henderson C., Gordon D., Auger K., Wright D., RA Collins J., Raisen C., Dyer L., Leung K., Robertson L., Ambridge K., RA Leongamornlert D., McGuire S., Gilderthorp R., Griffiths C., RA Manthravadi D., Nichol S., Barker G., Whitehead S., Kay M., Brown J., RA Murnane C., Gray E., Humphries M., Sycamore N., Barker D., RA Saunders D., Wallis J., Babbage A., Hammond S., RA Mashreghi-Mohammadi M., Barr L., Martin S., Wray P., Ellington A., RA Matthews N., Ellwood M., Woodmansey R., Clark G., Cooper J., RA Tromans A., Grafham D., Skuce C., Pandian R., Andrews R., Harrison E., RA Kimberley A., Garnett J., Fosker N., Hall R., Garner P., Kelly D., RA Bird C., Palmer S., Gehring I., Berger A., Dooley C.M., Ersan-Urun Z., RA Eser C., Geiger H., Geisler M., Karotki L., Kirn A., Konantz J., RA Konantz M., Oberlander M., Rudolph-Geiger S., Teucke M., Lanz C., RA Raddatz G., Osoegawa K., Zhu B., Rapp A., Widaa S., Langford C., RA Yang F., Schuster S.C., Carter N.P., Harrow J., Ning Z., Herrero J., RA Searle S.M., Enright A., Geisler R., Plasterk R.H., Lee C., RA Westerfield M., de Jong P.J., Zon L.I., Postlethwait J.H., RA Nusslein-Volhard C., Hubbard T.J., Roest Crollius H., Rogers J., RA Stemple D.L.; RT "The zebrafish reference genome sequence and its relationship to the RT human genome."; RL Nature 496:498-503(2013). RN [2] {ECO:0000313|Ensembl:ENSDARP00000135644} RP IDENTIFICATION. RC STRAIN=Tuebingen {ECO:0000313|Ensembl:ENSDARP00000135644}; RG Ensembl; RL Submitted (NOV-2015) to UniProtKB. CC -!- CAUTION: The sequence shown here is derived from an Ensembl CC automatic analysis pipeline and should be considered as CC preliminary data. {ECO:0000313|Ensembl:ENSDARP00000135644}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; CU469520; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; CU694198; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR RefSeq; NP_001232897.3; NM_001245968.3. DR UniGene; Dr.79695; -. DR Ensembl; ENSDART00000162175; ENSDARP00000135644; ENSDARG00000103516. DR GeneID; 571870; -. DR KEGG; dre:571870; -. DR CTD; 9632; -. DR ZFIN; ZDB-GENE-030131-4487; sec24c. DR GeneTree; ENSGT00590000082962; -. DR KO; K14007; -. DR Reactome; R-DRE-204005; COPII (Coat Protein 2) Mediated Vesicle Transport. DR Reactome; R-DRE-5694530; Cargo concentration in the ER. DR Reactome; R-DRE-983170; Antigen Presentation: Folding, assembly and peptide loading of class I MHC. DR Proteomes; UP000000437; Chromosome 12. DR ExpressionAtlas; A0A0R4IMX2; baseline. DR GO; GO:0030127; C:COPII vesicle coat; IEA:InterPro. DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro. DR GO; GO:0006888; P:ER to Golgi vesicle-mediated transport; IEA:InterPro. DR GO; GO:0006886; P:intracellular protein transport; IEA:InterPro. DR Gene3D; 3.40.20.10; -; 1. DR Gene3D; 3.40.50.410; -; 1. DR InterPro; IPR029006; ADF-H/Gelsolin-like_dom. DR InterPro; IPR007123; Gelsolin-like_dom. DR InterPro; IPR006900; Sec23/24_helical_dom. DR InterPro; IPR006896; Sec23/24_trunk_dom. DR InterPro; IPR012990; Sec23_24_beta_S. DR InterPro; IPR002035; VWF_A. DR InterPro; IPR006895; Znf_Sec23_Sec24. DR Pfam; PF00626; Gelsolin; 1. DR Pfam; PF08033; Sec23_BS; 1. DR Pfam; PF04815; Sec23_helical; 1. DR Pfam; PF04811; Sec23_trunk; 1. DR Pfam; PF04810; zf-Sec23_Sec24; 1. DR SUPFAM; SSF53300; SSF53300; 1. DR SUPFAM; SSF81811; SSF81811; 1. DR SUPFAM; SSF82754; SSF82754; 1. DR SUPFAM; SSF82919; SSF82919; 1. PE 1: Evidence at protein level; KW Complete proteome {ECO:0000313|Proteomes:UP000000437}; KW Protein transport {ECO:0000256|SAAS:SAAS00721504}; KW Proteomics identification {ECO:0000213|PeptideAtlas:A0A0R4IMX2}; KW Reference proteome {ECO:0000313|Proteomes:UP000000437}; KW Transport {ECO:0000256|SAAS:SAAS00721758}. FT DOMAIN 576 614 zf-Sec23_Sec24. {ECO:0000259|Pfam: FT PF04810}. FT DOMAIN 653 897 Sec23_trunk. {ECO:0000259|Pfam:PF04811}. FT DOMAIN 902 985 Sec23_BS. {ECO:0000259|Pfam:PF08033}. FT DOMAIN 998 1098 Sec23_helical. {ECO:0000259|Pfam: FT PF04815}. FT DOMAIN 1118 1188 Gelsolin-like. {ECO:0000259|Pfam: FT PF00626}. SQ SEQUENCE 1248 AA; 134951 MW; 994A54D3BFB96EBC CRC64; MNVNQQPHMA SPYGQPQPGY QRYPQPGYQR YPQPGYQRYP QPGYGGGHVP SGYPAQYAPD NGPGSGYQQG PPQGMREPPT SGTPPVSGAQ SYSQFGQGET QNGPPPMVAP PQGTLVSQPH TPNAVSLSGP TQPPYGQQFG SPPIGMQQMT NQMASMQVGS TAPSPAGPGY APPSTAQAPI SAAYTPSAPP TFPPTSSAPS QPPPTEAVAQ PPPLPYYGAP PPAQQPFPNA VSTFSSAGPT QPQAPPSVSQ QSFPQAPAVS QPPFSTAPPP GPSQSYGGPL PPTQPSFQRA PLPTSQPGVF PGGPPPTSTH SQLPGPMPPQ PPVSQPSPYY SEPPPTTASF PPQVGAPPRP PLAGMQGPPM ASQGPLMASH GPPGASQEPP LQLQGPPMGS QGPTMAQVNH VPPSQPGMPP GPINASLSGP PPQPGMQGYP PQQNGAFGQV RGPQPGYAAP PYSGQPNYGA PPAAPAPAPA APKRLDPDSI PSPIQVIEDD KANKGSQPFT TGVRGQAPPL VTTRFQVKDQ GNASPRYIRC TAYNMPCNSD MAKQSQVPLA AVIKPLATLP PDESPPYLVD HGESGPIRCN RCKAYMCPFM QFIEGGRRFQ CGFCSCVTEV PPHYFQHLDH TGKRVDCYER PELSMGSYEF MATVDYCKNN KFPQPPAFIF LIDVSYNAVK NGMVGMVCQE LKTLMDYLPR ENPDVESNVR VGFVTYNKVL HFYNVKASLA QPQMLVVSDV ADMFVPLLDG FLVNVSESRV VIESLLDQIP EMFADTRETE TVFGPVIQAG LEALKAADCA GKLFIFHSSL PIAEAPGKLK NREDKKLVGT DKEKSLFQPQ VSFYNTLAKD CVAQGCCVDL FLFPNQYVDV ATLGVVPTST GGSIYKYTYF QASSDQERFL NDLRRDVQKQ MGFDAVMRVR TSTGIRATDF FGSFYMSNTT DVELAGLDCD KTVTVEFRHD DKLSEETGAL MQCAVLYTSC SGQRRLRVHN MAVNCCSQLA DLYRNCETDT IINFFVKYAY RSVLSSPTKN VRDSLVNQCA QILACYRKNC ASPSSAGQLI LPECMKLLPV YLNCVLKSDV LQPGADVSLD DRAYLRQLVS AMDVAESHVF FYPRLLPLQK LDAESTSLPL AVRDSEERLS RGGVYLLENG LNIFIWVGVN AQQELLQNIF GTPAFSQIDP SMTSLPALDN PFSKRLKEII ESIRAQRSRY MKLMVVKQED KLELIFKHFL VEDKSNNGGA SYVDFLCHMH KEIRQLLS //