ID A0A0R4IHF0_DANRE Unreviewed; 491 AA. AC A0A0R4IHF0; DT 20-JUN-2018, integrated into UniProtKB/TrEMBL. DT 20-JUN-2018, sequence version 1. DT 20-JUN-2018, entry version 1. DE SubName: Full=Protein kinase C and casein kinase substrate in neurons 2 {ECO:0000313|Ensembl:ENSDARP00000133109}; GN Name=pacsin2 {ECO:0000313|Ensembl:ENSDARP00000133109, GN ECO:0000313|ZFIN:ZDB-GENE-040426-2596}; OS Danio rerio (Zebrafish) (Brachydanio rerio). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; OC Cyprinidae; Danio. OX NCBI_TaxID=7955 {ECO:0000313|Ensembl:ENSDARP00000133109, ECO:0000313|Proteomes:UP000000437}; RN [1] {ECO:0000313|Ensembl:ENSDARP00000133109, ECO:0000313|Proteomes:UP000000437} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Tuebingen {ECO:0000313|Ensembl:ENSDARP00000133109, RC ECO:0000313|Proteomes:UP000000437}; RX PubMed=23594743; DOI=10.1038/nature12111; RA Howe K., Clark M.D., Torroja C.F., Torrance J., Berthelot C., RA Muffato M., Collins J.E., Humphray S., McLaren K., Matthews L., RA McLaren S., Sealy I., Caccamo M., Churcher C., Scott C., Barrett J.C., RA Koch R., Rauch G.J., White S., Chow W., Kilian B., Quintais L.T., RA Guerra-Assuncao J.A., Zhou Y., Gu Y., Yen J., Vogel J.H., Eyre T., RA Redmond S., Banerjee R., Chi J., Fu B., Langley E., Maguire S.F., RA Laird G.K., Lloyd D., Kenyon E., Donaldson S., Sehra H., RA Almeida-King J., Loveland J., Trevanion S., Jones M., Quail M., RA Willey D., Hunt A., Burton J., Sims S., McLay K., Plumb B., Davis J., RA Clee C., Oliver K., Clark R., Riddle C., Elliot D., Threadgold G., RA Harden G., Ware D., Begum S., Mortimore B., Kerry G., Heath P., RA Phillimore B., Tracey A., Corby N., Dunn M., Johnson C., Wood J., RA Clark S., Pelan S., Griffiths G., Smith M., Glithero R., Howden P., RA Barker N., Lloyd C., Stevens C., Harley J., Holt K., Panagiotidis G., RA Lovell J., Beasley H., Henderson C., Gordon D., Auger K., Wright D., RA Collins J., Raisen C., Dyer L., Leung K., Robertson L., Ambridge K., RA Leongamornlert D., McGuire S., Gilderthorp R., Griffiths C., RA Manthravadi D., Nichol S., Barker G., Whitehead S., Kay M., Brown J., RA Murnane C., Gray E., Humphries M., Sycamore N., Barker D., RA Saunders D., Wallis J., Babbage A., Hammond S., RA Mashreghi-Mohammadi M., Barr L., Martin S., Wray P., Ellington A., RA Matthews N., Ellwood M., Woodmansey R., Clark G., Cooper J., RA Tromans A., Grafham D., Skuce C., Pandian R., Andrews R., Harrison E., RA Kimberley A., Garnett J., Fosker N., Hall R., Garner P., Kelly D., RA Bird C., Palmer S., Gehring I., Berger A., Dooley C.M., Ersan-Urun Z., RA Eser C., Geiger H., Geisler M., Karotki L., Kirn A., Konantz J., RA Konantz M., Oberlander M., Rudolph-Geiger S., Teucke M., Lanz C., RA Raddatz G., Osoegawa K., Zhu B., Rapp A., Widaa S., Langford C., RA Yang F., Schuster S.C., Carter N.P., Harrow J., Ning Z., Herrero J., RA Searle S.M., Enright A., Geisler R., Plasterk R.H., Lee C., RA Westerfield M., de Jong P.J., Zon L.I., Postlethwait J.H., RA Nusslein-Volhard C., Hubbard T.J., Roest Crollius H., Rogers J., RA Stemple D.L.; RT "The zebrafish reference genome sequence and its relationship to the RT human genome."; RL Nature 496:498-503(2013). RN [2] {ECO:0000313|Ensembl:ENSDARP00000133109} RP IDENTIFICATION. RC STRAIN=Tuebingen {ECO:0000313|Ensembl:ENSDARP00000133109}; RG Ensembl; RL Submitted (NOV-2015) to UniProtKB. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; CU694238; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; CU695158; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR RefSeq; NP_996952.2; NM_207069.2. DR UniGene; Dr.121469; -. DR STRING; 7955.ENSDARP00000124182; -. DR Ensembl; ENSDART00000159094; ENSDARP00000133109; ENSDARG00000078014. DR GeneID; 404601; -. DR KEGG; dre:404601; -. DR CTD; 11252; -. DR ZFIN; ZDB-GENE-040426-2596; pacsin2. DR GeneTree; ENSGT00510000046376; -. DR KO; K20123; -. DR Reactome; R-DRE-8856828; Clathrin-mediated endocytosis. DR Proteomes; UP000000437; Chromosome 4. DR Bgee; ENSDARG00000078014; -. DR GO; GO:0005768; C:endosome; IBA:GO_Central. DR GO; GO:0030036; P:actin cytoskeleton organization; IEA:InterPro. DR GO; GO:0070836; P:caveola assembly; IEA:InterPro. DR GO; GO:0097320; P:plasma membrane tubulation; IEA:InterPro. DR GO; GO:0030100; P:regulation of endocytosis; IBA:GO_Central. DR CDD; cd07679; F-BAR_PACSIN2; 1. DR Gene3D; 1.20.1270.60; -; 1. DR InterPro; IPR027267; AH/BAR_dom_sf. DR InterPro; IPR031160; F_BAR. DR InterPro; IPR001060; FCH_dom. DR InterPro; IPR028521; PACSIN2. DR InterPro; IPR037453; PACSIN2_F-BAR. DR InterPro; IPR036028; SH3-like_dom_sf. DR InterPro; IPR001452; SH3_domain. DR PANTHER; PTHR23065:SF14; PTHR23065:SF14; 1. DR Pfam; PF00611; FCH; 1. DR Pfam; PF14604; SH3_9; 1. DR PRINTS; PR00452; SH3DOMAIN. DR SMART; SM00055; FCH; 1. DR SMART; SM00326; SH3; 1. DR SUPFAM; SSF103657; SSF103657; 1. DR SUPFAM; SSF50044; SSF50044; 1. DR PROSITE; PS51741; F_BAR; 1. DR PROSITE; PS50002; SH3; 1. PE 4: Predicted; KW Complete proteome {ECO:0000313|Proteomes:UP000000437}; KW Reference proteome {ECO:0000313|Proteomes:UP000000437}. SQ SEQUENCE 491 AA; 56216 MW; 36E76FC3463A4F78 CRC64; MSDFNDSLID VSSDSFWEVG NYKRSVKRVD DGNRLCNDLM SCLHERARIE KSYSTQLTDW AKRWRQTIEK GPQYGTVERA WCALMTEAEK VSDLHMEVKA ALMAEDFEKI KNWQKDAYHK QMIGGFKETK EAEDGFRKAQ KPWAKKLKEM ETMKKAYHTA CKEEKTATSR ENSSKLDNSN PEAQKKLQEK VEKCQQEVQK TKERYEKSLE DLDKVTPQYM ENMEQVFEQW QQFEGKRLSF FKEVLLEVKQ HLDLSSNHKY TTVYHTLQDT IQGADPQEDL KWFRSNHGPG MTMNWPQFEE WSMDLNRTLS RRETKRRPAE GVTLTAISHN PEQSSRVSSV PAVSSSEAAC LNPFDDDDDD EDEDEEPVVT HTHSSPVKHE EAVAQTSAAV EKAPAPAAIT AADDDDDEES GNPFSSSSAN GNPFEEEPST EMCVPVRAVY DYEGQEQDEL SFKAGDELVK LSEEDEQGWC KGRLSNGTVG LYPANYVEDL Q //