ID A0A0R4IGQ8_DANRE Unreviewed; 1632 AA. AC A0A0R4IGQ8; DT 20-JAN-2016, integrated into UniProtKB/TrEMBL. DT 20-JUN-2018, sequence version 2. DT 03-AUG-2022, entry version 29. DE SubName: Full=Myomesin 1b {ECO:0000313|Ensembl:ENSDARP00000133738}; GN OrderedLocusNames=myom1b {ECO:0000313|Ensembl:ENSDARP00000133738, GN ECO:0000313|ZFIN:ZDB-GENE-080416-2}; GN ORFNames=SO:0001217 {ECO:0000313|ZFIN:ZDB-GENE-080416-2}; OS Danio rerio (Zebrafish) (Brachydanio rerio). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; OC Danionidae; Danioninae; Danio. OX NCBI_TaxID=7955 {ECO:0000313|Ensembl:ENSDARP00000133738}; RN [1] {ECO:0000313|Ensembl:ENSDARP00000133738} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Tuebingen {ECO:0000313|Ensembl:ENSDARP00000133738}; RX PubMed=23594743; DOI=10.1038/nature12111; RA Howe K., Clark M.D., Torroja C.F., Torrance J., Berthelot C., Muffato M., RA Collins J.E., Humphray S., McLaren K., Matthews L., McLaren S., Sealy I., RA Caccamo M., Churcher C., Scott C., Barrett J.C., Koch R., Rauch G.J., RA White S., Chow W., Kilian B., Quintais L.T., Guerra-Assuncao J.A., Zhou Y., RA Gu Y., Yen J., Vogel J.H., Eyre T., Redmond S., Banerjee R., Chi J., Fu B., RA Langley E., Maguire S.F., Laird G.K., Lloyd D., Kenyon E., Donaldson S., RA Sehra H., Almeida-King J., Loveland J., Trevanion S., Jones M., Quail M., RA Willey D., Hunt A., Burton J., Sims S., McLay K., Plumb B., Davis J., RA Clee C., Oliver K., Clark R., Riddle C., Elliot D., Threadgold G., RA Harden G., Ware D., Begum S., Mortimore B., Kerry G., Heath P., RA Phillimore B., Tracey A., Corby N., Dunn M., Johnson C., Wood J., Clark S., RA Pelan S., Griffiths G., Smith M., Glithero R., Howden P., Barker N., RA Lloyd C., Stevens C., Harley J., Holt K., Panagiotidis G., Lovell J., RA Beasley H., Henderson C., Gordon D., Auger K., Wright D., Collins J., RA Raisen C., Dyer L., Leung K., Robertson L., Ambridge K., Leongamornlert D., RA McGuire S., Gilderthorp R., Griffiths C., Manthravadi D., Nichol S., RA Barker G., Whitehead S., Kay M., Brown J., Murnane C., Gray E., RA Humphries M., Sycamore N., Barker D., Saunders D., Wallis J., Babbage A., RA Hammond S., Mashreghi-Mohammadi M., Barr L., Martin S., Wray P., RA Ellington A., Matthews N., Ellwood M., Woodmansey R., Clark G., Cooper J., RA Tromans A., Grafham D., Skuce C., Pandian R., Andrews R., Harrison E., RA Kimberley A., Garnett J., Fosker N., Hall R., Garner P., Kelly D., Bird C., RA Palmer S., Gehring I., Berger A., Dooley C.M., Ersan-Urun Z., Eser C., RA Geiger H., Geisler M., Karotki L., Kirn A., Konantz J., Konantz M., RA Oberlander M., Rudolph-Geiger S., Teucke M., Lanz C., Raddatz G., RA Osoegawa K., Zhu B., Rapp A., Widaa S., Langford C., Yang F., RA Schuster S.C., Carter N.P., Harrow J., Ning Z., Herrero J., Searle S.M., RA Enright A., Geisler R., Plasterk R.H., Lee C., Westerfield M., RA de Jong P.J., Zon L.I., Postlethwait J.H., Nusslein-Volhard C., RA Hubbard T.J., Roest Crollius H., Rogers J., Stemple D.L.; RT "The zebrafish reference genome sequence and its relationship to the human RT genome."; RL Nature 496:498-503(2013). RN [2] {ECO:0000313|Ensembl:ENSDARP00000133738} RP IDENTIFICATION. RC STRAIN=Tuebingen {ECO:0000313|Ensembl:ENSDARP00000133738}; RG Ensembl; RL Submitted (NOV-2015) to UniProtKB. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; CU607104; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR AlphaFoldDB; A0A0R4IGQ8; -. DR Ensembl; ENSDART00000166724.3; ENSDARP00000133738.2; ENSDARG00000104836.4. DR ZFIN; ZDB-GENE-080416-2; myom1b. DR ZFIN; ZDB-GENE-080416-2; SO:0001217. DR GeneTree; ENSGT00940000154982; -. DR Proteomes; UP000814640; Chromosome 7. DR Bgee; ENSDARG00000104836; Expressed in heart and 11 other tissues. DR ExpressionAtlas; A0A0R4IGQ8; baseline. DR GO; GO:0031430; C:M band; IBA:GO_Central. DR GO; GO:0051015; F:actin filament binding; IBA:GO_Central. DR GO; GO:0019900; F:kinase binding; IBA:GO_Central. DR GO; GO:0006936; P:muscle contraction; IBA:GO_Central. DR CDD; cd00063; FN3; 5. DR Gene3D; 2.60.40.10; -; 12. DR InterPro; IPR003961; FN3_dom. DR InterPro; IPR036116; FN3_sf. DR InterPro; IPR007110; Ig-like_dom. DR InterPro; IPR036179; Ig-like_dom_sf. DR InterPro; IPR013783; Ig-like_fold. DR InterPro; IPR013098; Ig_I-set. DR InterPro; IPR003599; Ig_sub. DR InterPro; IPR003598; Ig_sub2. DR Pfam; PF00041; fn3; 5. DR Pfam; PF07679; I-set; 4. DR SMART; SM00060; FN3; 5. DR SMART; SM00409; IG; 4. DR SMART; SM00408; IGc2; 4. DR SUPFAM; SSF48726; SSF48726; 6. DR SUPFAM; SSF49265; SSF49265; 3. DR PROSITE; PS50853; FN3; 5. DR PROSITE; PS50835; IG_LIKE; 5. PE 1: Evidence at protein level; KW Immunoglobulin domain {ECO:0000256|ARBA:ARBA00023319}; KW Proteomics identification {ECO:0007829|PeptideAtlas:A0A0R4IGQ8}; KW Repeat {ECO:0000256|ARBA:ARBA00022737}. FT DOMAIN 166..257 FT /note="Ig-like" FT /evidence="ECO:0000259|PROSITE:PS50835" FT DOMAIN 272..379 FT /note="Ig-like" FT /evidence="ECO:0000259|PROSITE:PS50835" FT DOMAIN 393..488 FT /note="Fibronectin type-III" FT /evidence="ECO:0000259|PROSITE:PS50853" FT DOMAIN 519..613 FT /note="Fibronectin type-III" FT /evidence="ECO:0000259|PROSITE:PS50853" FT DOMAIN 620..713 FT /note="Fibronectin type-III" FT /evidence="ECO:0000259|PROSITE:PS50853" FT DOMAIN 719..817 FT /note="Fibronectin type-III" FT /evidence="ECO:0000259|PROSITE:PS50853" FT DOMAIN 824..923 FT /note="Fibronectin type-III" FT /evidence="ECO:0000259|PROSITE:PS50853" FT DOMAIN 922..1008 FT /note="Ig-like" FT /evidence="ECO:0000259|PROSITE:PS50835" FT DOMAIN 1141..1227 FT /note="Ig-like" FT /evidence="ECO:0000259|PROSITE:PS50835" FT DOMAIN 1367..1445 FT /note="Ig-like" FT /evidence="ECO:0000259|PROSITE:PS50835" FT REGION 10..45 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT REGION 478..498 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT REGION 1468..1578 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT REGION 1590..1632 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COMPBIAS 24..45 FT /note="Polar residues" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COMPBIAS 1468..1565 FT /note="Polar residues" FT /evidence="ECO:0000256|SAM:MobiDB-lite" SQ SEQUENCE 1632 AA; 181219 MW; 9AC55602767B554F CRC64; MSGSIPFYQK HHRHYDRSYR SRETESAISQ YQQSSSSYSA HSSKSSKGIR AATYTALDEG LSPLPKRAKP TYLAMDKENQ IIGYVVPIFR GSHDFASGLS DSEEARAKVS AGYVSGRELF SSGVESERSR RTVMRESAER IQLSKRIHEN EEYHKRQNED SLMHTPEFVI KPRSHTVWEK QCVRLHCTIS GWPDPRVVWY KNNVSIDPMS NPGKYKVESS YNVHSLEINR CDFDDTAQYR VSAMNSKGEN SAYASVVVKR FKGEFDESLP SPRLPPCLEY GVTFETHIVE KFGVAFGREG ETLSFGCSVI IYPSLQRFQP EIEWYRDDKL LVPSKWVQMH WSGDRATLTL THLNKEDEGL YTLRVITKSG FQSHSAYVFV RDADADVAGA PGAPLDVHCL DANKDYVIVA WKQPAVDGGS AILGYFVDRC EVGTTHWAQC NDTPVKFARF PVTGLIEGRS YTFRVRAVNK AGMSHPSRVS EPVAAMDPAD RSRKGASAPW TGQIIVTEEE PVEGVVPGRP QELSVIEATK NYVVLSWKPP GEKGHEGVMY YVEKCVSGTD SWQRVNTEIP VKSPRFALFD LAEGKSYRFR VRCCNSAGVG EPSEPTDATT VGDKLDIPSA PGRVVPTRNT DTSVVISWEA SRDAKELVGY YIESSIAGSN TWEPCNNKPV KATRFICHGL TTGESYVFRV RAVNAAGISE FSQESEAIVV KAAIASPAPP YGISVLECVR DSMVLAWKQP TFIGGADITG YFVDYREVTG GVPGKWHEAN IKAISERAYR VSELKENMLY QFQVRAANMA GVGIPSLPSE TFKCEEWTIA VPGPPHDLQV QEVRKNSLVL LWKPPVYQGR DAVNGYYIDI KEAEADFEMW RGVNEKATDK AFFKVNDLKG GESYVFRVRA QNKAGVGKAS DPTEPVEAVT KPGTAEIVVN VDDEGVISLN FECSNLTGDS KFVWSKNYEE MTEPERMTLE TKGSKSKAIF NSPSEEDLGI YSCFVTHTDG ASASYTFSEE ALKELLKVSH DHKFPIIPLK TELAVELLEK GRVRFWLQAA KISANAKVEY VFNDNMISQG EKYKMNFDKN TGIIEMFMES LGKEDEGTFT FQLQDGKATN QSSLVLIGDV FKQLQKESEF QRKEWHRKQG PHFVEYLGYE VTPECCVRLK CKVGNMKKDS TALWYKDGRE VKVDEKLDFS EGVLTLEIAQ ISKKDAGIYE VVLKDERGKD TSTLNLTDQG FKDLMNQVFS VIANSSTPLK IQSTEEGIRL YTFVSYYNDE LHVTWHHKDA AIAFTERIKS GVVGEQLWLQ ISEPTEKDKG KYAIEFFDGK GGLRRTVELA GQAFDDAFAE FQRLKAAAIA ERNRARVAGG LPDVVTIQEG KSLNLTCNIW GDPVPEVTWL KNEREMVSDD HYILKFESGK FASFTITSVN TADSGKYSIL VKNKYGTESG DFTLNVIESV PDFGVVSYLA DAEGNINVGS TMTPVQRKPS SRSFPTTPST VTSTLTSTPT NANPQNKTTA NENQSSSTDP PSPISDNQTT STPLNPPDQS SGTPVPQNQT SDPPIHSNPQ CSSPTEEEEE SVDDGKMTAV VEVTVNLGLS PLKADAAEDL TEAVSTPEPE TACPTEPEND SEEPTPDPDT AN //