ID A0A0R4IGQ8_DANRE Unreviewed; 1632 AA. AC A0A0R4IGQ8; DT 20-JAN-2016, integrated into UniProtKB/TrEMBL. DT 20-JUN-2018, sequence version 2. DT 05-DEC-2018, entry version 17. DE SubName: Full=Myomesin 1b {ECO:0000313|Ensembl:ENSDARP00000133738}; GN Name=myom1b {ECO:0000313|Ensembl:ENSDARP00000133738, GN ECO:0000313|ZFIN:ZDB-GENE-080416-2}; OS Danio rerio (Zebrafish) (Brachydanio rerio). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; OC Cyprinidae; Danio. OX NCBI_TaxID=7955 {ECO:0000313|Ensembl:ENSDARP00000133738, ECO:0000313|Proteomes:UP000000437}; RN [1] {ECO:0000313|Ensembl:ENSDARP00000133738, ECO:0000313|Proteomes:UP000000437} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Tuebingen {ECO:0000313|Ensembl:ENSDARP00000133738, RC ECO:0000313|Proteomes:UP000000437}; RX PubMed=23594743; DOI=10.1038/nature12111; RA Howe K., Clark M.D., Torroja C.F., Torrance J., Berthelot C., RA Muffato M., Collins J.E., Humphray S., McLaren K., Matthews L., RA McLaren S., Sealy I., Caccamo M., Churcher C., Scott C., Barrett J.C., RA Koch R., Rauch G.J., White S., Chow W., Kilian B., Quintais L.T., RA Guerra-Assuncao J.A., Zhou Y., Gu Y., Yen J., Vogel J.H., Eyre T., RA Redmond S., Banerjee R., Chi J., Fu B., Langley E., Maguire S.F., RA Laird G.K., Lloyd D., Kenyon E., Donaldson S., Sehra H., RA Almeida-King J., Loveland J., Trevanion S., Jones M., Quail M., RA Willey D., Hunt A., Burton J., Sims S., McLay K., Plumb B., Davis J., RA Clee C., Oliver K., Clark R., Riddle C., Elliot D., Threadgold G., RA Harden G., Ware D., Begum S., Mortimore B., Kerry G., Heath P., RA Phillimore B., Tracey A., Corby N., Dunn M., Johnson C., Wood J., RA Clark S., Pelan S., Griffiths G., Smith M., Glithero R., Howden P., RA Barker N., Lloyd C., Stevens C., Harley J., Holt K., Panagiotidis G., RA Lovell J., Beasley H., Henderson C., Gordon D., Auger K., Wright D., RA Collins J., Raisen C., Dyer L., Leung K., Robertson L., Ambridge K., RA Leongamornlert D., McGuire S., Gilderthorp R., Griffiths C., RA Manthravadi D., Nichol S., Barker G., Whitehead S., Kay M., Brown J., RA Murnane C., Gray E., Humphries M., Sycamore N., Barker D., RA Saunders D., Wallis J., Babbage A., Hammond S., RA Mashreghi-Mohammadi M., Barr L., Martin S., Wray P., Ellington A., RA Matthews N., Ellwood M., Woodmansey R., Clark G., Cooper J., RA Tromans A., Grafham D., Skuce C., Pandian R., Andrews R., Harrison E., RA Kimberley A., Garnett J., Fosker N., Hall R., Garner P., Kelly D., RA Bird C., Palmer S., Gehring I., Berger A., Dooley C.M., Ersan-Urun Z., RA Eser C., Geiger H., Geisler M., Karotki L., Kirn A., Konantz J., RA Konantz M., Oberlander M., Rudolph-Geiger S., Teucke M., Lanz C., RA Raddatz G., Osoegawa K., Zhu B., Rapp A., Widaa S., Langford C., RA Yang F., Schuster S.C., Carter N.P., Harrow J., Ning Z., Herrero J., RA Searle S.M., Enright A., Geisler R., Plasterk R.H., Lee C., RA Westerfield M., de Jong P.J., Zon L.I., Postlethwait J.H., RA Nusslein-Volhard C., Hubbard T.J., Roest Crollius H., Rogers J., RA Stemple D.L.; RT "The zebrafish reference genome sequence and its relationship to the RT human genome."; RL Nature 496:498-503(2013). RN [2] {ECO:0000313|Ensembl:ENSDARP00000133738} RP IDENTIFICATION. RC STRAIN=Tuebingen {ECO:0000313|Ensembl:ENSDARP00000133738}; RG Ensembl; RL Submitted (NOV-2015) to UniProtKB. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; CU607104; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR Ensembl; ENSDART00000166724; ENSDARP00000133738; ENSDARG00000104836. DR ZFIN; ZDB-GENE-080416-2; myom1b. DR GeneTree; ENSGT00940000154982; -. DR Proteomes; UP000000437; Chromosome 7. DR ExpressionAtlas; A0A0R4IGQ8; baseline. DR GO; GO:0031430; C:M band; IBA:GO_Central. DR GO; GO:0030017; C:sarcomere; IBA:GO_Central. DR GO; GO:0005865; C:striated muscle thin filament; IBA:GO_Central. DR GO; GO:0030018; C:Z disc; IBA:GO_Central. DR GO; GO:0051015; F:actin filament binding; IBA:GO_Central. DR GO; GO:0019900; F:kinase binding; IBA:GO_Central. DR GO; GO:0051371; F:muscle alpha-actinin binding; IBA:GO_Central. DR GO; GO:0008307; F:structural constituent of muscle; IBA:GO_Central. DR GO; GO:0048739; P:cardiac muscle fiber development; IBA:GO_Central. DR GO; GO:0055008; P:cardiac muscle tissue morphogenesis; IBA:GO_Central. DR GO; GO:0055003; P:cardiac myofibril assembly; IBA:GO_Central. DR GO; GO:0006936; P:muscle contraction; IBA:GO_Central. DR GO; GO:0045214; P:sarcomere organization; IBA:GO_Central. DR GO; GO:0030241; P:skeletal muscle myosin thick filament assembly; IBA:GO_Central. DR GO; GO:0030240; P:skeletal muscle thin filament assembly; IBA:GO_Central. DR CDD; cd00063; FN3; 5. DR Gene3D; 2.60.40.10; -; 12. DR InterPro; IPR003961; FN3_dom. DR InterPro; IPR036116; FN3_sf. DR InterPro; IPR007110; Ig-like_dom. DR InterPro; IPR036179; Ig-like_dom_sf. DR InterPro; IPR013783; Ig-like_fold. DR InterPro; IPR013098; Ig_I-set. DR InterPro; IPR003599; Ig_sub. DR InterPro; IPR003598; Ig_sub2. DR Pfam; PF00041; fn3; 5. DR Pfam; PF07679; I-set; 4. DR SMART; SM00060; FN3; 5. DR SMART; SM00409; IG; 4. DR SMART; SM00408; IGc2; 4. DR SUPFAM; SSF48726; SSF48726; 6. DR SUPFAM; SSF49265; SSF49265; 3. DR PROSITE; PS50853; FN3; 5. DR PROSITE; PS50835; IG_LIKE; 5. PE 1: Evidence at protein level; KW Complete proteome {ECO:0000313|Proteomes:UP000000437}; KW Proteomics identification {ECO:0000213|PeptideAtlas:A0A0R4IGQ8}; KW Reference proteome {ECO:0000313|Proteomes:UP000000437}; KW Repeat {ECO:0000256|SAAS:SAAS00923712}. FT DOMAIN 166 257 Ig-like. {ECO:0000259|PROSITE:PS50835}. FT DOMAIN 272 379 Ig-like. {ECO:0000259|PROSITE:PS50835}. FT DOMAIN 393 488 Fibronectin type-III. FT {ECO:0000259|PROSITE:PS50853}. FT DOMAIN 519 613 Fibronectin type-III. FT {ECO:0000259|PROSITE:PS50853}. FT DOMAIN 620 713 Fibronectin type-III. FT {ECO:0000259|PROSITE:PS50853}. FT DOMAIN 719 817 Fibronectin type-III. FT {ECO:0000259|PROSITE:PS50853}. FT DOMAIN 824 923 Fibronectin type-III. FT {ECO:0000259|PROSITE:PS50853}. FT DOMAIN 922 1008 Ig-like. {ECO:0000259|PROSITE:PS50835}. FT DOMAIN 1141 1227 Ig-like. {ECO:0000259|PROSITE:PS50835}. FT DOMAIN 1367 1445 Ig-like. {ECO:0000259|PROSITE:PS50835}. SQ SEQUENCE 1632 AA; 181219 MW; 9AC55602767B554F CRC64; MSGSIPFYQK HHRHYDRSYR SRETESAISQ YQQSSSSYSA HSSKSSKGIR AATYTALDEG LSPLPKRAKP TYLAMDKENQ IIGYVVPIFR GSHDFASGLS DSEEARAKVS AGYVSGRELF SSGVESERSR RTVMRESAER IQLSKRIHEN EEYHKRQNED SLMHTPEFVI KPRSHTVWEK QCVRLHCTIS GWPDPRVVWY KNNVSIDPMS NPGKYKVESS YNVHSLEINR CDFDDTAQYR VSAMNSKGEN SAYASVVVKR FKGEFDESLP SPRLPPCLEY GVTFETHIVE KFGVAFGREG ETLSFGCSVI IYPSLQRFQP EIEWYRDDKL LVPSKWVQMH WSGDRATLTL THLNKEDEGL YTLRVITKSG FQSHSAYVFV RDADADVAGA PGAPLDVHCL DANKDYVIVA WKQPAVDGGS AILGYFVDRC EVGTTHWAQC NDTPVKFARF PVTGLIEGRS YTFRVRAVNK AGMSHPSRVS EPVAAMDPAD RSRKGASAPW TGQIIVTEEE PVEGVVPGRP QELSVIEATK NYVVLSWKPP GEKGHEGVMY YVEKCVSGTD SWQRVNTEIP VKSPRFALFD LAEGKSYRFR VRCCNSAGVG EPSEPTDATT VGDKLDIPSA PGRVVPTRNT DTSVVISWEA SRDAKELVGY YIESSIAGSN TWEPCNNKPV KATRFICHGL TTGESYVFRV RAVNAAGISE FSQESEAIVV KAAIASPAPP YGISVLECVR DSMVLAWKQP TFIGGADITG YFVDYREVTG GVPGKWHEAN IKAISERAYR VSELKENMLY QFQVRAANMA GVGIPSLPSE TFKCEEWTIA VPGPPHDLQV QEVRKNSLVL LWKPPVYQGR DAVNGYYIDI KEAEADFEMW RGVNEKATDK AFFKVNDLKG GESYVFRVRA QNKAGVGKAS DPTEPVEAVT KPGTAEIVVN VDDEGVISLN FECSNLTGDS KFVWSKNYEE MTEPERMTLE TKGSKSKAIF NSPSEEDLGI YSCFVTHTDG ASASYTFSEE ALKELLKVSH DHKFPIIPLK TELAVELLEK GRVRFWLQAA KISANAKVEY VFNDNMISQG EKYKMNFDKN TGIIEMFMES LGKEDEGTFT FQLQDGKATN QSSLVLIGDV FKQLQKESEF QRKEWHRKQG PHFVEYLGYE VTPECCVRLK CKVGNMKKDS TALWYKDGRE VKVDEKLDFS EGVLTLEIAQ ISKKDAGIYE VVLKDERGKD TSTLNLTDQG FKDLMNQVFS VIANSSTPLK IQSTEEGIRL YTFVSYYNDE LHVTWHHKDA AIAFTERIKS GVVGEQLWLQ ISEPTEKDKG KYAIEFFDGK GGLRRTVELA GQAFDDAFAE FQRLKAAAIA ERNRARVAGG LPDVVTIQEG KSLNLTCNIW GDPVPEVTWL KNEREMVSDD HYILKFESGK FASFTITSVN TADSGKYSIL VKNKYGTESG DFTLNVIESV PDFGVVSYLA DAEGNINVGS TMTPVQRKPS SRSFPTTPST VTSTLTSTPT NANPQNKTTA NENQSSSTDP PSPISDNQTT STPLNPPDQS SGTPVPQNQT SDPPIHSNPQ CSSPTEEEEE SVDDGKMTAV VEVTVNLGLS PLKADAAEDL TEAVSTPEPE TACPTEPEND SEEPTPDPDT AN //