ID A0A0P0VD52_ORYSJ Unreviewed; 1117 AA. AC A0A0P0VD52; Q0JFZ3; Q5JKZ9; DT 26-FEB-2020, integrated into UniProtKB/TrEMBL. DT 26-FEB-2020, sequence version 1. DT 29-MAY-2024, entry version 20. DE RecName: Full=beta-galactosidase {ECO:0000256|ARBA:ARBA00012756}; DE EC=3.2.1.23 {ECO:0000256|ARBA:ARBA00012756}; DE AltName: Full=Lactase {ECO:0000256|ARBA:ARBA00032230}; GN OrderedLocusNames=Os01g0952600 {ECO:0000313|EMBL:BAS76255.1}; GN ORFNames=OsJ_04784 {ECO:0000313|EMBL:EEE56015.1}, OSNPB_010952600 GN {ECO:0000313|EMBL:BAS76255.1}; OS Oryza sativa subsp. japonica (Rice). OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade; OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa. OX NCBI_TaxID=39947 {ECO:0000313|EMBL:EEE56015.1}; RN [1] {ECO:0000313|Proteomes:UP000059680} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=cv. Nipponbare {ECO:0000313|Proteomes:UP000059680}; RX PubMed=16100779; DOI=10.1038/nature03895; RG International rice genome sequencing project (IRGSP); RA Matsumoto T., Wu J., Kanamori H., Katayose Y., Fujisawa M., Namiki N., RA Mizuno H., Yamamoto K., Antonio B.A., Baba T., Sakata K., Nagamura Y., RA Aoki H., Arikawa K., Arita K., Bito T., Chiden Y., Fujitsuka N., RA Fukunaka R., Hamada M., Harada C., Hayashi A., Hijishita S., Honda M., RA Hosokawa S., Ichikawa Y., Idonuma A., Iijima M., Ikeda M., Ikeno M., RA Ito K., Ito S., Ito T., Ito Y., Ito Y., Iwabuchi A., Kamiya K., RA Karasawa W., Kurita K., Katagiri S., Kikuta A., Kobayashi H., Kobayashi N., RA Machita K., Maehara T., Masukawa M., Mizubayashi T., Mukai Y., Nagasaki H., RA Nagata Y., Naito S., Nakashima M., Nakama Y., Nakamichi Y., Nakamura M., RA Meguro A., Negishi M., Ohta I., Ohta T., Okamoto M., Ono N., Saji S., RA Sakaguchi M., Sakai K., Shibata M., Shimokawa T., Song J., Takazaki Y., RA Terasawa K., Tsugane M., Tsuji K., Ueda S., Waki K., Yamagata H., RA Yamamoto M., Yamamoto S., Yamane H., Yoshiki S., Yoshihara R., Yukawa K., RA Zhong H., Yano M., Yuan Q., Ouyang S., Liu J., Jones K.M., Gansberger K., RA Moffat K., Hill J., Bera J., Fadrosh D., Jin S., Johri S., Kim M., RA Overton L., Reardon M., Tsitrin T., Vuong H., Weaver B., Ciecko A., RA Tallon L., Jackson J., Pai G., Aken S.V., Utterback T., Reidmuller S., RA Feldblyum T., Hsiao J., Zismann V., Iobst S., de Vazeille A.R., Buell C.R., RA Ying K., Li Y., Lu T., Huang Y., Zhao Q., Feng Q., Zhang L., Zhu J., RA Weng Q., Mu J., Lu Y., Fan D., Liu Y., Guan J., Zhang Y., Yu S., Liu X., RA Zhang Y., Hong G., Han B., Choisne N., Demange N., Orjeda G., Samain S., RA Cattolico L., Pelletier E., Couloux A., Segurens B., Wincker P., D'Hont A., RA Scarpelli C., Weissenbach J., Salanoubat M., Quetier F., Yu Y., Kim H.R., RA Rambo T., Currie J., Collura K., Luo M., Yang T., Ammiraju J.S.S., RA Engler F., Soderlund C., Wing R.A., Palmer L.E., de la Bastide M., RA Spiegel L., Nascimento L., Zutavern T., O'Shaughnessy A., Dike S., RA Dedhia N., Preston R., Balija V., McCombie W.R., Chow T., Chen H., RA Chung M., Chen C., Shaw J., Wu H., Hsiao K., Chao Y., Chu M., Cheng C., RA Hour A., Lee P., Lin S., Lin Y., Liou J., Liu S., Hsing Y., Raghuvanshi S., RA Mohanty A., Bharti A.K., Gaur A., Gupta V., Kumar D., Ravi V., Vij S., RA Kapur A., Khurana P., Khurana P., Khurana J.P., Tyagi A.K., Gaikwad K., RA Singh A., Dalal V., Srivastava S., Dixit A., Pal A.K., Ghazi I.A., RA Yadav M., Pandit A., Bhargava A., Sureshbabu K., Batra K., Sharma T.R., RA Mohapatra T., Singh N.K., Messing J., Nelson A.B., Fuks G., Kavchok S., RA Keizer G., Linton E., Llaca V., Song R., Tanyolac B., Young S., Ho-Il K., RA Hahn J.H., Sangsakoo G., Vanavichit A., de Mattos Luiz.A.T., Zimmer P.D., RA Malone G., Dellagostin O., de Oliveira A.C., Bevan M., Bancroft I., RA Minx P., Cordum H., Wilson R., Cheng Z., Jin W., Jiang J., Leong S.A., RA Iwama H., Gojobori T., Itoh T., Niimura Y., Fujii Y., Habara T., Sakai H., RA Sato Y., Wilson G., Kumar K., McCouch S., Juretic N., Hoen D., Wright S., RA Bruskiewich R., Bureau T., Miyao A., Hirochika H., Nishikawa T., RA Kadowaki K., Sugiura M., Burr B., Sasaki T.; RT "The map-based sequence of the rice genome."; RL Nature 436:793-800(2005). RN [2] {ECO:0000313|EMBL:EEE56015.1} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RX PubMed=15685292; DOI=10.1371/journal.pbio.0030038; RA Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S., RA Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L., RA Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J., RA Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X., RA Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y., RA Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L., RA Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H., RA Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z., RA Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L., RA Fang L., Lei T., Chen C., Chen H., Xu Z., Li H., Huang H., Zhang F., Xu H., RA Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q., Li W., RA Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J., Gao L., RA Zheng W., Hao B., Liu S., Wang W., Yuan L., Cao M., McDermott J., RA Samudrala R., Wang J., Wong G.K., Yang H.; RT "The genomes of Oryza sativa: a history of duplications."; RL PLoS Biol. 3:266-281(2005). RN [3] {ECO:0000313|EMBL:EEE56015.1} RP NUCLEOTIDE SEQUENCE. RA Wang J., Li R., Fan W., Huang Q., Zhang J., Zhou Y., Hu Y., Zi S., Li J., RA Ni P., Zheng H., Zhang Y., Zhao M., Hao Q., McDermott J., Samudrala R., RA Kristiansen K., Wong G.K.-S.; RT "Improved gene annotation of the rice (Oryza sativa) genomes."; RL Submitted (DEC-2008) to the EMBL/GenBank/DDBJ databases. RN [4] {ECO:0000313|EMBL:BAS76255.1} RP NUCLEOTIDE SEQUENCE. RX PubMed=23299411; DOI=10.1093/pcp/pcs183; RA Sakai H., Lee S.S., Tanaka T., Numa H., Kim J., Kawahara Y., Wakimoto H., RA Yang C.C., Iwamoto M., Abe T., Yamada Y., Muto A., Inokuchi H., Ikemura T., RA Matsumoto T., Sasaki T., Itoh T.; RT "Rice Annotation Project Database (RAP-DB): an integrative and interactive RT database for rice genomics."; RL Plant Cell Physiol. 54:E6-E6(2013). RN [5] {ECO:0000313|EMBL:BAS76255.1, ECO:0000313|Proteomes:UP000059680} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=cv. Nipponbare {ECO:0000313|Proteomes:UP000059680}; RX PubMed=24280374; DOI=10.1186/1939-8433-6-4; RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R., RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L., RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H., RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.; RT "Improvement of the Oryza sativa Nipponbare reference genome using next RT generation sequence and optical map data."; RL Rice 6:4-4(2013). RN [6] {ECO:0000313|EMBL:BAS76255.1} RP NUCLEOTIDE SEQUENCE. RA Sakai H., Kawahara Y., Matsumoto T., Buell C.R., Itoh T.; RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases. CC -!- CATALYTIC ACTIVITY: CC Reaction=Hydrolysis of terminal non-reducing beta-D-galactose residues CC in beta-D-galactosides.; EC=3.2.1.23; CC Evidence={ECO:0000256|ARBA:ARBA00001412}; CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 2 family. CC {ECO:0000256|ARBA:ARBA00007401, ECO:0000256|RuleBase:RU361154}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AP014957; BAS76255.1; -; Genomic_DNA. DR EMBL; CM000138; EEE56015.1; -; Genomic_DNA. DR RefSeq; XP_015620054.1; XM_015764568.1. DR SMR; A0A0P0VD52; -. DR STRING; 39947.Q5JKZ9; -. DR CAZy; GH2; Glycoside Hydrolase Family 2. DR PaxDb; 39947-Q5JKZ9; -. DR EnsemblPlants; Os01t0952600-01; Os01t0952600-01; Os01g0952600. DR GeneID; 4325748; -. DR Gramene; Os01t0952600-01; Os01t0952600-01; Os01g0952600. DR KEGG; osa:4325748; -. DR eggNOG; KOG2024; Eukaryota. DR OMA; EITDFCH; -. DR OrthoDB; 276651at2759; -. DR Proteomes; UP000007752; Chromosome 1. DR Proteomes; UP000059680; Chromosome 1. DR GO; GO:0009341; C:beta-galactosidase complex; IEA:InterPro. DR GO; GO:0004565; F:beta-galactosidase activity; IEA:UniProtKB-EC. DR GO; GO:0030246; F:carbohydrate binding; IEA:InterPro. DR GO; GO:0005990; P:lactose catabolic process; IEA:TreeGrafter. DR Gene3D; 2.70.98.10; -; 1. DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 1. DR Gene3D; 3.20.20.80; Glycosidases; 1. DR Gene3D; 2.60.40.10; Immunoglobulins; 2. DR InterPro; IPR004199; B-gal_small/dom_5. DR InterPro; IPR036156; Beta-gal/glucu_dom_sf. DR InterPro; IPR011013; Gal_mutarotase_sf_dom. DR InterPro; IPR008979; Galactose-bd-like_sf. DR InterPro; IPR014718; GH-type_carb-bd. DR InterPro; IPR006101; Glyco_hydro_2. DR InterPro; IPR023232; Glyco_hydro_2_AS. DR InterPro; IPR006103; Glyco_hydro_2_cat. DR InterPro; IPR023230; Glyco_hydro_2_CS. DR InterPro; IPR006102; Glyco_hydro_2_Ig-like. DR InterPro; IPR006104; Glyco_hydro_2_N. DR InterPro; IPR017853; Glycoside_hydrolase_SF. DR InterPro; IPR013783; Ig-like_fold. DR InterPro; IPR032312; LacZ_4. DR PANTHER; PTHR46323; BETA-GALACTOSIDASE; 1. DR PANTHER; PTHR46323:SF2; BETA-GALACTOSIDASE; 1. DR Pfam; PF02929; Bgal_small_N; 1. DR Pfam; PF00703; Glyco_hydro_2; 1. DR Pfam; PF02836; Glyco_hydro_2_C; 1. DR Pfam; PF02837; Glyco_hydro_2_N; 1. DR Pfam; PF16353; LacZ_4; 1. DR PRINTS; PR00132; GLHYDRLASE2. DR SMART; SM01038; Bgal_small_N; 1. DR SUPFAM; SSF51445; (Trans)glycosidases; 1. DR SUPFAM; SSF49303; beta-Galactosidase/glucuronidase domain; 2. DR SUPFAM; SSF74650; Galactose mutarotase-like; 1. DR SUPFAM; SSF49785; Galactose-binding domain-like; 1. DR PROSITE; PS00719; GLYCOSYL_HYDROL_F2_1; 1. DR PROSITE; PS00608; GLYCOSYL_HYDROL_F2_2; 1. PE 1: Evidence at protein level; KW Glycosidase {ECO:0000256|ARBA:ARBA00023295, ECO:0000256|RuleBase:RU361154}; KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU361154}; KW Proteomics identification {ECO:0007829|PeptideAtlas:A0A0P0VD52, KW ECO:0007829|ProteomicsDB:A0A0P0VD52}; KW Reference proteome {ECO:0000313|Proteomes:UP000059680}. FT DOMAIN 805..1099 FT /note="Beta galactosidase small chain/" FT /evidence="ECO:0000259|SMART:SM01038" SQ SEQUENCE 1117 AA; 126241 MW; B19894DBEDF76E07 CRC64; MAVASASALF SAKNLPHKPW EDPSFFRWRK REAHVPLRSH DTPEGALKYW HERRNVNYLN SDSAVWNDDA VRGALESAAF WSKGLPYVQT LSGYWKFLLA SSPESVPEKF YDAYFNDSDW EALPVPSNWQ MHGFDRPIYT NVTYPFTMNP PFVPNDNPTG CYRTVFRIPK EWKGRRILLH FEAVDSAFFA WVNGVPVGYS QDSRLPAEFE ITDFCHPCDS EKENVLAVQV MRWSDGSYLE DQDHWWLSGI HRDVLLVSKP QIFITDYFFK ATLDEGFRVA DIEVEVEIDS QKQDREHVST LSIEATLYDN YGPADVLTSD MSAASVANLK LKPASRPKHC YGFHGYVLGG KVENPKLWSS EHPNLYTLVV VLKDSNGKLI ECESCQVGIR NVVLAHKQML VNGCPVVIRG VNRHEHHPRV GKTNLEACMI KDLVLMRQNN INAVRNSHYP QHPRWYELCD IFGLYVIDEA NIETHGFDES SHFKHPTLEP FWASAMLDRV VGMVERDKNH ACIIVWSLGN ESSYGPNHSA MSGWIRGKDP TRPIHYEGGG SRTSSTDIVC PMYMRVWDIL KIAQDPSENR PLILCEYSHA MGNSNGNIDA YWMAIDNTVG LQGGFIWDWV DQGLLKEDAD GSKNWAYGGD FGDTPNDLNF CLNGIVWPDR TIHPAVHEVK YLYQPIKITM MDNMLKIENV HFFETTEALD FSWLLQGDGC ALGSGSLNVP SIAPQSTHLI NMKSSPWFTI WSTCVVKEIF LSINVKLRYQ TQWAKDGHIL ASAQICLPPK KGFVPHAIAL PRSSLVSERV GDHVLISKSN AWQIKVNSIS GTIDSWKVNN IELMSKGIHP CFWRTPTDND KGGFYTKPYV SRWREASLDN ISFYSSQFSL KELPDQTVEI STIYYGLPGN QPKPDETSLS DESESVLFRV QMRGRIYDSG DVILDYEVSP KNDLPPLPRV GVVFNADKSL SRAKWYGRGP FECYPDRKAA AHVGVYESGV DELHVPYIVP GECGGRADVR WVALQDADGF GLFASAYGES PPMQVSASYY GAAELDRATH NHKLVKGDDI EVHLDHKHMG LGGDDSWSPC VHEQYLLPPA RYAFSVRLCP LLPSSSCHDI YHSQLPC //