ID A0A0M3TC14_9ACTN Unreviewed; 858 AA. AC A0A0M3TC14; DT 09-DEC-2015, integrated into UniProtKB/TrEMBL. DT 09-DEC-2015, sequence version 1. DT 11-MAY-2016, entry version 6. DE RecName: Full=DNA helicase {ECO:0000256|SAAS:SAAS00553569}; DE EC=3.6.4.12 {ECO:0000256|SAAS:SAAS00553569}; GN ORFNames=AL705_02270 {ECO:0000313|EMBL:ALE19594.1}; OS Corynebacteriales bacterium X1698. OC Bacteria; Actinobacteria; Corynebacteriales. OX NCBI_TaxID=1562462 {ECO:0000313|EMBL:ALE19594.1}; RN [1] {ECO:0000313|EMBL:ALE19594.1, ECO:0000313|Proteomes:UP000068137} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=X1698 {ECO:0000313|EMBL:ALE19594.1, RC ECO:0000313|Proteomes:UP000068137}; RX PubMed=26659691; RA Nicholson A.C., Bell M., Humrighouse B.W., McQuiston J.R.; RT "Complete Genome Sequences for Two Strains of a Novel Fastidious, RT Partially Acid-Fast, Gram-Positive Corynebacterineae Bacterium, RT Derived from Human Clinical Samples."; RL Genome Announc. 3:e01462-15(2015). CC -!- CATALYTIC ACTIVITY: ATP + H(2)O = ADP + phosphate. CC {ECO:0000256|SAAS:SAAS00553768}. CC -!- SIMILARITY: Belongs to the helicase family. UvrD subfamily. CC {ECO:0000256|SAAS:SAAS00597767}. CC -!- SIMILARITY: Contains uvrD-like helicase ATP-binding domain. CC {ECO:0000256|SAAS:SAAS00553567}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; CP012390; ALE19594.1; -; Genomic_DNA. DR RefSeq; WP_053962655.1; NZ_CP012390.1. DR KEGG; cbq:AL705_02270; -. DR KO; K03657; -. DR Proteomes; UP000068137; Chromosome. DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW. DR GO; GO:0004003; F:ATP-dependent DNA helicase activity; IEA:InterPro. DR GO; GO:0003677; F:DNA binding; IEA:InterPro. DR Gene3D; 1.10.10.160; -; 1. DR Gene3D; 3.40.50.300; -; 4. DR InterPro; IPR013986; DExx_box_DNA_helicase_dom. DR InterPro; IPR014017; DNA_helicase_UvrD-like_C. DR InterPro; IPR000212; DNA_helicase_UvrD/REP. DR InterPro; IPR027417; P-loop_NTPase. DR InterPro; IPR014016; UvrD-like_ATP-bd. DR PANTHER; PTHR11070; PTHR11070; 2. DR Pfam; PF00580; UvrD-helicase; 1. DR Pfam; PF13361; UvrD_C; 1. DR SUPFAM; SSF52540; SSF52540; 2. DR PROSITE; PS51198; UVRD_HELICASE_ATP_BIND; 1. DR PROSITE; PS51217; UVRD_HELICASE_CTER; 1. PE 3: Inferred from homology; KW ATP-binding {ECO:0000256|SAAS:SAAS00553698}; KW Complete proteome {ECO:0000313|Proteomes:UP000068137}; KW Helicase {ECO:0000256|SAAS:SAAS00493105, ECO:0000313|EMBL:ALE19594.1}; KW Hydrolase {ECO:0000256|SAAS:SAAS00553587}; KW Nucleotide-binding {ECO:0000256|SAAS:SAAS00553576}. FT DOMAIN 31 318 UvrD-like helicase ATP-binding. FT {ECO:0000259|PROSITE:PS51198}. FT DOMAIN 319 637 UvrD-like helicase C-terminal. FT {ECO:0000259|PROSITE:PS51217}. SQ SEQUENCE 858 AA; 93843 MW; BB0ECB58F60660EB CRC64; MPVSGKASTS RTARAGWHRR RDPHAAEQLL EGLNPQQQQA VQHTGTPLLI VAGAGSGKTT VLTRRIAYVL ETQPVRASQI LAITFTNKAA AEMRERVQHI VGTEATYMWV STFHSMCVRI LRAQAAQLEV VNSNFTIYDA DDAKRLLTMI VKDLNLDPKK YAPKALANRI SNWKNELIDA ETAAADAHEG HFDKVASEVY GIYQARLRAA NAFDFDDLIG ETVALLESHP AIAQYYQRRF RHVLVDEYQD TNHAQYMLVR ALVGDGSNGV EPAELCVVGD ADQSIYAFRG ATIRNIVEFE RDFTNATTIL LEQNYRSTQN ILSAANAVID NNAGRRKKNL WTAAGDGPLI DLYVADNEHD EARFIGSEID KLHDEGMSYS DMAVFYRTNN GSRPLEDAFI RTGLPYKVVG GTRFYERMEV RDIVAYLKVV ENPADAVSLR RIINTPRRGI GDRAMSCLAM FAEQQGVSLW EACCRAQNGT VPFLNSRAEN AIAAFVSLIT GIQNHSAGAE HTAGADSLPD LGELVELVID RSGYRASLEG SNDPQDQARL DNLNELVSVA HEFSADAASL RALEESFAQD DTNGISAETV AEGTEGLAAP GSLAAFLERV SLTSDTDQIP DEDDGMITLM TLHSAKGLEF PVVFVTGWED GMFPHMRALA DENELSEERR LAYVGITRAK RKLYVTRAVV RSSWGQPQSN PQSRFLDEIP AHLLNVLREA PEFDDDDWSY GSSGHSWGTG GGSPWGAGSR SGGTGSREGK SSAHHVGRSG ISRSGRYGDV HKRWGNPVET RRMAPQIANP RHSSAISVEK GDRVVHDKYG LGKVLEVTGV GASATALVDF GSSGVVRLML IAAPIEKL //