ID A0A0M2AAW4_ENTFL Unreviewed; 642 AA. AC A0A0M2AAW4; DT 11-NOV-2015, integrated into UniProtKB/TrEMBL. DT 11-NOV-2015, sequence version 1. DT 08-JUN-2016, entry version 6. DE SubName: Full=PTS system, sucrose-specific IIBC component {ECO:0000313|EMBL:EOI97083.1}; GN ORFNames=UMC_01556 {ECO:0000313|EMBL:EOI97083.1}; OS Enterococcus faecalis EnGen0302. OC Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae; OC Enterococcus. OX NCBI_TaxID=1158660 {ECO:0000313|EMBL:EOI97083.1, ECO:0000313|Proteomes:UP000013839}; RN [1] {ECO:0000313|EMBL:EOI97083.1, ECO:0000313|Proteomes:UP000013839} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=CH116 {ECO:0000313|EMBL:EOI97083.1, RC ECO:0000313|Proteomes:UP000013839}; RG The Broad Institute Genome Sequencing Platform; RG The Broad Institute Genome Sequencing Center for Infectious Disease; RA Earl A.M., Gilmore M.S., Lebreton F., Walker B., Young S.K., Zeng Q., RA Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Alvarado L., RA Arachchi H.M., Berlin A.M., Chapman S.B., Dewar J., Goldberg J., RA Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Larimer J., RA McCowan C., Murphy C., Neiman D., Pearson M., Priest M., Roberts A., RA Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C., RA Birren B.; RT "The Genome Sequence of Enterococcus faecalis CH116."; RL Submitted (FEB-2013) to the EMBL/GenBank/DDBJ databases. CC -!- FUNCTION: The phosphoenolpyruvate-dependent sugar CC phosphotransferase system (sugar PTS), a major carbohydrate active CC -transport system, catalyzes the phosphorylation of incoming sugar CC substrates concomitantly with their translocation across the cell CC membrane. {ECO:0000256|SAAS:SAAS00547063}. CC -!- SIMILARITY: Contains PTS EIIA type-1 domain. CC {ECO:0000256|SAAS:SAAS00506360}. CC -!- SIMILARITY: Contains PTS EIIB type-1 domain. CC {ECO:0000256|SAAS:SAAS00515949}. CC -!- SIMILARITY: Contains PTS EIIC type-1 domain. CC {ECO:0000256|SAAS:SAAS00504904}. CC -!- CAUTION: The sequence shown here is derived from an CC EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is CC preliminary data. {ECO:0000313|EMBL:EOI97083.1}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AJEG01000010; EOI97083.1; -; Genomic_DNA. DR RefSeq; WP_002360285.1; NZ_KB947273.1. DR EnsemblBacteria; EOI97083; EOI97083; UMC_01556. DR Proteomes; UP000013839; Unassembled WGS sequence. DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW. DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW. DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW. DR GO; GO:0008982; F:protein-N(PI)-phosphohistidine-sugar phosphotransferase activity; IEA:InterPro. DR GO; GO:0009401; P:phosphoenolpyruvate-dependent sugar phosphotransferase system; IEA:UniProtKB-KW. DR Gene3D; 3.30.1360.60; -; 1. DR InterPro; IPR011055; Dup_hybrid_motif. DR InterPro; IPR018113; PTrfase_EIIB_Cys. DR InterPro; IPR001127; PTS_EIIA_1_perm. DR InterPro; IPR003352; PTS_EIIC. DR InterPro; IPR013013; PTS_EIIC_1. DR InterPro; IPR001996; PTS_IIB_1. DR InterPro; IPR010973; PTS_IIBC_sucr. DR Pfam; PF00358; PTS_EIIA_1; 1. DR Pfam; PF00367; PTS_EIIB; 1. DR Pfam; PF02378; PTS_EIIC; 1. DR SUPFAM; SSF51261; SSF51261; 1. DR SUPFAM; SSF55604; SSF55604; 1. DR TIGRFAMs; TIGR00826; EIIB_glc; 1. DR TIGRFAMs; TIGR00830; PTBA; 1. DR TIGRFAMs; TIGR01996; PTS-II-BC-sucr; 1. DR PROSITE; PS51093; PTS_EIIA_TYPE_1; 1. DR PROSITE; PS00371; PTS_EIIA_TYPE_1_HIS; 1. DR PROSITE; PS51098; PTS_EIIB_TYPE_1; 1. DR PROSITE; PS01035; PTS_EIIB_TYPE_1_CYS; 1. DR PROSITE; PS51103; PTS_EIIC_TYPE_1; 1. PE 4: Predicted; KW Cell membrane {ECO:0000256|SAAS:SAAS00467886}; KW Complete proteome {ECO:0000313|Proteomes:UP000013839}; KW Kinase {ECO:0000256|SAAS:SAAS00500788}; KW Membrane {ECO:0000256|SAAS:SAAS00468091, ECO:0000256|SAM:Phobius}; KW Phosphotransferase system {ECO:0000256|SAAS:SAAS00467990}; KW Sugar transport {ECO:0000256|SAAS:SAAS00468169}; KW Transferase {ECO:0000256|SAAS:SAAS00515976}; KW Transmembrane {ECO:0000256|SAAS:SAAS00467970, KW ECO:0000256|SAM:Phobius}; KW Transmembrane helix {ECO:0000256|SAAS:SAAS00468233, KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|SAAS:SAAS00468113}. FT TRANSMEM 112 133 Helical. {ECO:0000256|SAM:Phobius}. FT TRANSMEM 153 173 Helical. {ECO:0000256|SAM:Phobius}. FT TRANSMEM 185 203 Helical. {ECO:0000256|SAM:Phobius}. FT TRANSMEM 215 241 Helical. {ECO:0000256|SAM:Phobius}. FT TRANSMEM 262 281 Helical. {ECO:0000256|SAM:Phobius}. FT TRANSMEM 293 317 Helical. {ECO:0000256|SAM:Phobius}. FT TRANSMEM 329 348 Helical. {ECO:0000256|SAM:Phobius}. FT TRANSMEM 368 390 Helical. {ECO:0000256|SAM:Phobius}. FT TRANSMEM 397 416 Helical. {ECO:0000256|SAM:Phobius}. FT TRANSMEM 436 462 Helical. {ECO:0000256|SAM:Phobius}. FT DOMAIN 5 88 PTS EIIB type-1. {ECO:0000259|PROSITE: FT PS51098}. FT DOMAIN 120 478 PTS EIIC type-1. {ECO:0000259|PROSITE: FT PS51103}. FT DOMAIN 508 612 PTS EIIA type-1. {ECO:0000259|PROSITE: FT PS51093}. SQ SEQUENCE 642 AA; 69478 MW; D4D08B8E47A909AD CRC64; MAENYQQAAK DIIQLIGMDN IISVTHCQTR LRFILKDHEQ VDGKQLEKID LVKGVFYNGG QYQVILGTGI VTKVYDEIEK LGINVVSKAE QTAILKNNET GMRKTMRILS EIFIPIVPVI AATGLFLGLK GVIFNDTFLQ LFGASVANIP ESFQQIVSVI TDTVFAFLPA LIVWSTFKAF NATPVIGIVI GLMMVSPILP NAYAVATPDS GVKAIMAFGF IPVVGAQGSV LSAIAAGIIG AKIELFFRKK MPNILDQIFT PFMTMLITFL IMILGIGPIL HTVELGMVDV VQWLIGLPLG LGGFVIGASY PLMVLIGIHH TLTMVETSLL ANTGFNALIT ICAMYGFANV GSCLAFAKKA QDSKVKSTAI GSMLSQLFGV SEPVLFGLLI RWNLKPLLCV LFTSGLGGAI LAIFHIQSNS YGLAVIPSFL MYIYSAHQLV IYLLVALLSV GVCYALTSLF AIPQEVLISD KVIEEEEREV FEMQHNTLDE QLFSPVTGYA MNLTAVNDPV FSSEMMGKGL AIMPTANKVY APADGLLNLV AETGHAYGIQ TDAGAEVLIH IGIDTVTLGQ EVFQTQVTQG HRVKKGDLLG TFDRKAIKEA GLDSTVMVII TNTSSYLSVE PMMSDHNEIT PEQIILNLNT PN //