ID   A0A0L0BVI2_LUCCU        Unreviewed;       232 AA.
AC   A0A0L0BVI2;
DT   11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT   11-NOV-2015, sequence version 1.
DT   12-APR-2017, entry version 6.
DE   RecName: Full=SAGA-associated factor 11 homolog {ECO:0000256|HAMAP-Rule:MF_03047};
GN   Name=Sgf11 {ECO:0000256|HAMAP-Rule:MF_03047};
GN   ORFNames=FF38_11604 {ECO:0000313|EMBL:KNC23993.1};
OS   Lucilia cuprina (Green bottle fly) (Australian sheep blowfly).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
OC   Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha;
OC   Oestroidea; Calliphoridae; Luciliinae; Lucilia.
OX   NCBI_TaxID=7375 {ECO:0000313|EMBL:KNC23993.1, ECO:0000313|Proteomes:UP000037069};
RN   [1] {ECO:0000313|EMBL:KNC23993.1, ECO:0000313|Proteomes:UP000037069}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LS {ECO:0000313|EMBL:KNC23993.1,
RC   ECO:0000313|Proteomes:UP000037069};
RC   TISSUE=Full body {ECO:0000313|EMBL:KNC23993.1};
RX   PubMed=26108605; DOI=10.1038/ncomms8344;
RA   Anstead C.A., Korhonen P.K., Young N.D., Hall R.S., Jex A.R.,
RA   Murali S.C., Hughes D.S., Lee S.F., Perry T., Stroehlein A.J.,
RA   Ansell B.R., Breugelmans B., Hofmann A., Qu J., Dugan S., Lee S.L.,
RA   Chao H., Dinh H., Han Y., Doddapaneni H.V., Worley K.C., Muzny D.M.,
RA   Ioannidis P., Waterhouse R.M., Zdobnov E.M., James P.J., Bagnall N.H.,
RA   Kotze A.C., Gibbs R.A., Richards S., Batterham P., Gasser R.B.;
RT   "Lucilia cuprina genome unlocks parasitic fly biology to underpin
RT   future interventions.";
RL   Nat. Commun. 6:7344-7344(2015).
CC   -!- FUNCTION: Component of the transcription regulatory histone
CC       acetylation (HAT) complex SAGA, a multiprotein complex that
CC       activates transcription by remodeling chromatin and mediating
CC       histone acetylation and deubiquitination. Within the SAGA complex,
CC       participates in a subcomplex that specifically deubiquitinates
CC       histone H2B. The SAGA complex is recruited to specific gene
CC       promoters by activators, where it is required for transcription.
CC       {ECO:0000256|HAMAP-Rule:MF_03047, ECO:0000256|RuleBase:RU261113}.
CC   -!- SUBUNIT: Component of some SAGA transcription coactivator-HAT
CC       complexes. Within the SAGA complex, participates to a subcomplex
CC       of SAGA called the DUB module (deubiquitination module).
CC       {ECO:0000256|HAMAP-Rule:MF_03047}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|HAMAP-Rule:MF_03047,
CC       ECO:0000256|RuleBase:RU261113}.
CC   -!- DOMAIN: The C-terminal SGF11-type zinc-finger domain forms part of
CC       the 'catalytic lobe' of the SAGA deubiquitination module.
CC       {ECO:0000256|HAMAP-Rule:MF_03047}.
CC   -!- DOMAIN: The long N-terminal helix forms part of the 'assembly
CC       lobe' of the SAGA deubiquitination module. {ECO:0000256|HAMAP-
CC       Rule:MF_03047}.
CC   -!- SIMILARITY: Belongs to the SGF11 family. {ECO:0000256|HAMAP-
CC       Rule:MF_03047, ECO:0000256|RuleBase:RU261113}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:KNC23993.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; JRES01001278; KNC23993.1; -; Genomic_DNA.
DR   EnsemblMetazoa; KNC23993; KNC23993; FF38_11604.
DR   Proteomes; UP000037069; Unassembled WGS sequence.
DR   GO; GO:0071819; C:DUBm complex; IEA:UniProtKB-HAMAP.
DR   GO; GO:0000124; C:SAGA complex; IEA:UniProtKB-HAMAP.
DR   GO; GO:0003713; F:transcription coactivator activity; IEA:UniProtKB-HAMAP.
DR   GO; GO:0008270; F:zinc ion binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0016578; P:histone deubiquitination; IEA:UniProtKB-HAMAP.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IEA:UniProtKB-HAMAP.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   HAMAP; MF_03047; Sgf11; 1.
DR   InterPro; IPR013246; SAGA_su_Sgf11.
DR   Pfam; PF08209; Sgf11; 1.
PE   3: Inferred from homology;
KW   Activator {ECO:0000256|HAMAP-Rule:MF_03047,
KW   ECO:0000256|RuleBase:RU261113};
KW   Chromatin regulator {ECO:0000256|HAMAP-Rule:MF_03047};
KW   Complete proteome {ECO:0000313|Proteomes:UP000037069};
KW   Metal-binding {ECO:0000256|HAMAP-Rule:MF_03047};
KW   Nucleus {ECO:0000256|HAMAP-Rule:MF_03047};
KW   Reference proteome {ECO:0000313|Proteomes:UP000037069};
KW   Transcription {ECO:0000256|HAMAP-Rule:MF_03047};
KW   Transcription regulation {ECO:0000256|HAMAP-Rule:MF_03047};
KW   Zinc {ECO:0000256|HAMAP-Rule:MF_03047};
KW   Zinc-finger {ECO:0000256|HAMAP-Rule:MF_03047}.
FT   ZN_FING     139    160       SGF11-type. {ECO:0000256|HAMAP-Rule:
FT                                MF_03047}.
SQ   SEQUENCE   232 AA;  24990 MW;  0C41E885CC3CC908 CRC64;
     MSTGAPNNNN AASSNNSGSK TTTNSTSSTK VPAGNEKSNN VTTTTQNANT STAAILKSYR
     EIIKDPKSLD EAANYLYQTL LDDAIVGVFI EIHHLRKTGN LTALDGVPDE EAETSSFRIV
     DMPNFDIFGI STAKKPMDCT CPNCDRPVSA ARFAPHLEKC MGMGRISSRI ASRRLATKES
     NSASSSSSSS YLQTNAGSDD EDDVDWSSEK RRKKSSQNSR NNGSKKNNGK TF
//