ID A0A0K0P9K1_9GEMI Unreviewed; 135 AA. AC A0A0K0P9K1; DT 11-NOV-2015, integrated into UniProtKB/TrEMBL. DT 11-NOV-2015, sequence version 1. DT 14-DEC-2022, entry version 20. DE RecName: Full=Transcriptional activator protein {ECO:0000256|ARBA:ARBA00014388, ECO:0000256|RuleBase:RU363028}; DE Short=TrAP {ECO:0000256|RuleBase:RU363028}; GN Name=AC2 {ECO:0000313|EMBL:AKQ21214.1}; OS Clerodendron yellow mosaic virus. OC Viruses; Monodnaviria; Shotokuvirae; Cressdnaviricota; Repensiviricetes; OC Geplafuvirales; Geminiviridae; Begomovirus. OX NCBI_TaxID=326811 {ECO:0000313|EMBL:AKQ21214.1}; RN [1] {ECO:0000313|EMBL:AKQ21214.1} RP NUCLEOTIDE SEQUENCE. RC STRAIN=MJGD1 {ECO:0000313|EMBL:AKQ21214.1}; RA Jaidi M., Srivastava A., Kumar S., Raj S.K.; RT "Molecular characterization of Clerodendron yellow mosaic virus causing RT yellow mosaic disease in Duranta erecta in India."; RL Submitted (MAY-2015) to the EMBL/GenBank/DDBJ databases. CC -!- FUNCTION: Strong activator of the late viral genes promoters. Acts as a CC suppressor of RNA-mediated gene silencing, also known as post- CC transcriptional gene silencing (PTGS), a mechanism of plant viral CC defense that limits the accumulation of viral RNAs. Also suppresses the CC host basal defense by interacting with and inhibiting SNF1 kinase, a CC key regulator of cell metabolism implicated in innate antiviral CC defense. Determines pathogenicity. {ECO:0000256|RuleBase:RU363028}. CC -!- SUBUNIT: Monomer. Homodimer. Homooligomer. Self-interaction correlates CC with nuclear localization and efficient activation of transcription. CC {ECO:0000256|RuleBase:RU363028}. CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}. Host CC cytoplasm {ECO:0000256|ARBA:ARBA00004192, CC ECO:0000256|RuleBase:RU363028}. Host nucleus CC {ECO:0000256|ARBA:ARBA00004147, ECO:0000256|RuleBase:RU363028}. Nucleus CC {ECO:0000256|ARBA:ARBA00004123}. CC -!- DOMAIN: The zinc finger and the transactivation region are involved in CC PTGS suppression. {ECO:0000256|RuleBase:RU363028}. CC -!- SIMILARITY: Belongs to the geminiviridae transcriptional activator CC protein family. {ECO:0000256|ARBA:ARBA00007672, CC ECO:0000256|RuleBase:RU363028}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; KR869857; AKQ21214.1; -; Genomic_DNA. DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. DR GO; GO:0030430; C:host cell cytoplasm; IEA:UniProtKB-SubCell. DR GO; GO:0019028; C:viral capsid; IEA:InterPro. DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW. DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. DR GO; GO:0005198; F:structural molecule activity; IEA:InterPro. DR InterPro; IPR000942; Gemini_AL2. DR Pfam; PF01440; Gemini_AL2; 1. DR PRINTS; PR00230; GEMCOATAL2. PE 3: Inferred from homology; KW Activator {ECO:0000256|ARBA:ARBA00023159, ECO:0000256|RuleBase:RU363028}; KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|RuleBase:RU363028}; KW Host cytoplasm {ECO:0000256|RuleBase:RU363028}; KW Host nucleus {ECO:0000256|ARBA:ARBA00022562, KW ECO:0000256|RuleBase:RU363028}; KW Host-virus interaction {ECO:0000256|RuleBase:RU363028}; KW Metal-binding {ECO:0000256|RuleBase:RU363028}; KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553}; KW Suppressor of RNA silencing {ECO:0000256|ARBA:ARBA00022463, KW ECO:0000256|RuleBase:RU363028}; Zinc {ECO:0000256|RuleBase:RU363028}; KW Zinc-finger {ECO:0000256|RuleBase:RU363028}. FT REGION 72..112 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" SQ SEQUENCE 135 AA; 15435 MW; 5B9FD4E5331B95C7 CRC64; MRPSSPSTSR STQVPIKVQH RIAKRRAIRR KRIDLKCGCS YYLHINCHNH GFTHRGTHHC SSSDEWRVYL GGSKSPLFQD PKPPGQTILP EPRHNNNPDP VQPQPEESTG TTQMLHRLPD LDEFTSSDWS FLNGL //