ID A0A0J1ZMJ8_ECOLX Unreviewed; 326 AA. AC A0A0J1ZMJ8; DT 14-OCT-2015, integrated into UniProtKB/TrEMBL. DT 14-OCT-2015, sequence version 1. DT 07-OCT-2020, entry version 46. DE SubName: Full=IS5 family transposase {ECO:0000313|EMBL:OJR06705.1}; DE SubName: Full=IS5 transposase and trans-activator {ECO:0000313|EMBL:AUG93711.1}; DE SubName: Full=IS5-like element IS5 family transposase {ECO:0000313|EMBL:RWZ91345.1}; DE SubName: Full=IS5/IS1182 family transposase {ECO:0000313|EMBL:AVU48516.1}; DE SubName: Full=Transposase (Identified by ISEscan HMM) {ECO:0000313|EMBL:VCZ14043.1}; GN Name=insH {ECO:0000313|EMBL:STE30437.1}; GN Synonyms=insH-6 {ECO:0000313|EMBL:AUG93711.1}, insH_1 GN {ECO:0000313|EMBL:STH85941.1}, insH_10 {ECO:0000313|EMBL:STI85366.1}, GN insH_11 {ECO:0000313|EMBL:STI85419.1}, insH_13 GN {ECO:0000313|EMBL:STI85903.1}, insH_14 {ECO:0000313|EMBL:STI86067.1}, GN insH_15 {ECO:0000313|EMBL:STI86453.1}, insH_16 GN {ECO:0000313|EMBL:STI86502.1}, insH_18 {ECO:0000313|EMBL:STI86991.1}, GN insH_2 {ECO:0000313|EMBL:STH87555.1}, insH_20 GN {ECO:0000313|EMBL:STI87725.1}, insH_21 {ECO:0000313|EMBL:STI88145.1}, GN insH_3 {ECO:0000313|EMBL:STI81999.1}, insH_4 GN {ECO:0000313|EMBL:STL82834.1}, insH_5 {ECO:0000313|EMBL:STQ33862.1}, GN insH_6 {ECO:0000313|EMBL:STI83188.1}, insH_7 GN {ECO:0000313|EMBL:VTQ21734.1}; GN ORFNames=AWB10_27880 {ECO:0000313|EMBL:AVU48516.1}, BANRA_05079 GN {ECO:0000313|EMBL:VCZ14043.1}, BK334_22180 GN {ECO:0000313|EMBL:OJP11470.1}, BK375_28090 GN {ECO:0000313|EMBL:OJR06705.1}, DM102_27980 GN {ECO:0000313|EMBL:RZB23298.1}, EQ823_26855 GN {ECO:0000313|EMBL:RWZ91345.1}, MS8345_02110 GN {ECO:0000313|EMBL:AUG93711.1}, NCTC10764_01302 GN {ECO:0000313|EMBL:STE54642.1}, NCTC12650_02271 GN {ECO:0000313|EMBL:VTQ21734.1}, NCTC13148_01801 GN {ECO:0000313|EMBL:STL74429.1}, NCTC13148_02110 GN {ECO:0000313|EMBL:STL76039.1}, NCTC13148_03190 GN {ECO:0000313|EMBL:STL82834.1}, NCTC13846_00992 GN {ECO:0000313|EMBL:STE30437.1}, NCTC8622_00952 GN {ECO:0000313|EMBL:STI81999.1}, NCTC8622_02203 GN {ECO:0000313|EMBL:STI83188.1}, NCTC8622_04457 GN {ECO:0000313|EMBL:STI85366.1}, NCTC8622_04512 GN {ECO:0000313|EMBL:STI85419.1}, NCTC8622_05012 GN {ECO:0000313|EMBL:STI85903.1}, NCTC8622_05182 GN {ECO:0000313|EMBL:STI86067.1}, NCTC8622_05576 GN {ECO:0000313|EMBL:STI86453.1}, NCTC8622_05627 GN {ECO:0000313|EMBL:STI86502.1}, NCTC8622_06140 GN {ECO:0000313|EMBL:STI86991.1}, NCTC8622_06900 GN {ECO:0000313|EMBL:STI87725.1}, NCTC8622_07338 GN {ECO:0000313|EMBL:STI88145.1}, NCTC9036_00813 GN {ECO:0000313|EMBL:STQ33862.1}, NCTC9050_00944 GN {ECO:0000313|EMBL:STH85941.1}, NCTC9050_02636 GN {ECO:0000313|EMBL:STH87555.1}, SAMEA3752559_03305 GN {ECO:0000313|EMBL:SVF38503.1}; OS Escherichia coli. OG Plasmid unnamed3 {ECO:0000313|EMBL:AVU48516.1}. OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; OC Enterobacteriaceae; Escherichia. OX NCBI_TaxID=562 {ECO:0000313|EMBL:OJR06705.1, ECO:0000313|Proteomes:UP000184355}; RN [1] {ECO:0000313|EMBL:OJR06705.1, ECO:0000313|Proteomes:UP000184355, ECO:0000313|Proteomes:UP000184459} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=559 {ECO:0000313|EMBL:OJP11470.1, RC ECO:0000313|Proteomes:UP000184459}, and 675 RC {ECO:0000313|EMBL:OJR06705.1, ECO:0000313|Proteomes:UP000184355}; RA Wang Y., Zhang R., Li J., Wu Z., Wenjuan Y., Schwarz S., Tyrrell J., RA Zheng Y., Wang S., Shen Z., Liu Z., Lei L., Li M., Zhang Q., Wu C., RA Zhang Q., Wu Y., Walsh T., Shen J.; RT "Comprehensive resistome analysis reveals the prevalence of NDM and MCR-1 RT in Chinese poultry production."; RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases. RN [2] {ECO:0000313|EMBL:AVU48516.1, ECO:0000313|Proteomes:UP000324160} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=165 {ECO:0000313|EMBL:AVU48516.1, RC ECO:0000313|Proteomes:UP000324160}; RC PLASMID=unnamed3 {ECO:0000313|EMBL:AVU48516.1, RC ECO:0000313|Proteomes:UP000324160}; RA Hoffmann M., Sanchez M., Timme R., Bry L.; RT "Whole genome sequencing of cultured foodborne pathogen."; RL Submitted (MAR-2017) to the EMBL/GenBank/DDBJ databases. RN [3] {ECO:0000313|EMBL:AUG93711.1, ECO:0000313|Proteomes:UP000233584} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=MS8345 {ECO:0000313|EMBL:AUG93711.1, RC ECO:0000313|Proteomes:UP000233584}; RA Forde B.M., Zowawi H.M., Harris P., Roberts L., Ibrahim E., Shaikh N., RA Deshmukh A., Al Maslamani M., Cottrell K., Trembizki E., Sundac L., Yu H., RA Li J., Schembri M.A., Whiley D., Paterson D.L., Beatson S.A.; RT "Mcr-1 mediated colistin resistant Escherichia coli ST95 from Qatar."; RL Submitted (DEC-2017) to the EMBL/GenBank/DDBJ databases. RN [4] {ECO:0000313|EMBL:RZB23298.1, ECO:0000313|Proteomes:UP000292504} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=ZRUEC59 {ECO:0000313|EMBL:RZB23298.1, RC ECO:0000313|Proteomes:UP000292504}; RX PubMed=30510766; RA Rafaque Z., Dasti J.I., Andrews S.C.; RT "Draft genome sequence of a uropathogenic Escherichia coli isolate (ST38 RT O1:H15) from Pakistan, an emerging multidrug-resistant sequence type with a RT high virulence profile."; RL New Microbes New Infect 27:1-2(2018). RN [5] {ECO:0000313|Proteomes:UP000254079, ECO:0000313|Proteomes:UP000254255, ECO:0000313|Proteomes:UP000254870} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=NCTC10764 {ECO:0000313|EMBL:STE54642.1, RC ECO:0000313|Proteomes:UP000255201}, NCTC13148 RC {ECO:0000313|EMBL:STL74429.1, ECO:0000313|Proteomes:UP000254255}, RC NCTC13846 {ECO:0000313|EMBL:STE30437.1, RC ECO:0000313|Proteomes:UP000255209}, NCTC8622 RC {ECO:0000313|EMBL:STI81999.1, ECO:0000313|Proteomes:UP000254079}, RC NCTC9036 {ECO:0000313|EMBL:STQ33862.1, RC ECO:0000313|Proteomes:UP000254870}, NCTC9050 RC {ECO:0000313|EMBL:STH85941.1, ECO:0000313|Proteomes:UP000254972}, and RC VREC0543 {ECO:0000313|EMBL:SVF38503.1, RC ECO:0000313|Proteomes:UP000259784}; RG Pathogen Informatics; RA Doyle S.; RL Submitted (JUN-2018) to the EMBL/GenBank/DDBJ databases. RN [6] {ECO:0000313|EMBL:VCZ14043.1, ECO:0000313|Proteomes:UP000272353} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Ecoli018 {ECO:0000313|EMBL:VCZ14043.1}; RA Noll B N.; RL Submitted (OCT-2018) to the EMBL/GenBank/DDBJ databases. RN [7] {ECO:0000313|EMBL:RWZ91345.1, ECO:0000313|Proteomes:UP000290836} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=EC318 {ECO:0000313|EMBL:RWZ91345.1, RC ECO:0000313|Proteomes:UP000290836}; RA Yasir M.; RT "Genomic characterization of multidrug resistant E. coli from western Saudi RT Arabia."; RL Submitted (JAN-2019) to the EMBL/GenBank/DDBJ databases. RN [8] {ECO:0000313|EMBL:VTQ21734.1, ECO:0000313|Proteomes:UP000411984} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=NCTC12650 {ECO:0000313|EMBL:VTQ21734.1, RC ECO:0000313|Proteomes:UP000411984}; RG Pathogen Informatics; RL Submitted (MAY-2019) to the EMBL/GenBank/DDBJ databases. CC -!- FUNCTION: Involved in the transposition of the insertion sequence IS5. CC {ECO:0000256|ARBA:ARBA00003544}. CC -!- SIMILARITY: Belongs to the transposase 11 family. CC {ECO:0000256|ARBA:ARBA00010075}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; CP025401; AUG93711.1; -; Genomic_DNA. DR EMBL; CP020512; AVU48516.1; -; Genomic_DNA. DR EMBL; MOIL01000023; OJP11470.1; -; Genomic_DNA. DR EMBL; MOKA01000167; OJR06705.1; -; Genomic_DNA. DR EMBL; SCGD01000145; RWZ91345.1; -; Genomic_DNA. DR EMBL; QKMW01000088; RZB23298.1; -; Genomic_DNA. DR EMBL; UFZG01000001; STE30437.1; -; Genomic_DNA. DR EMBL; UFZL01000001; STE54642.1; -; Genomic_DNA. DR EMBL; UGBX01000001; STH85941.1; -; Genomic_DNA. DR EMBL; UGBX01000001; STH87555.1; -; Genomic_DNA. DR EMBL; UGCP01000002; STI81999.1; -; Genomic_DNA. DR EMBL; UGCP01000002; STI83188.1; -; Genomic_DNA. DR EMBL; UGCP01000002; STI85366.1; -; Genomic_DNA. DR EMBL; UGCP01000002; STI85419.1; -; Genomic_DNA. DR EMBL; UGCP01000002; STI85903.1; -; Genomic_DNA. DR EMBL; UGCP01000002; STI86067.1; -; Genomic_DNA. DR EMBL; UGCP01000002; STI86453.1; -; Genomic_DNA. DR EMBL; UGCP01000002; STI86502.1; -; Genomic_DNA. DR EMBL; UGCP01000002; STI86991.1; -; Genomic_DNA. DR EMBL; UGCP01000002; STI87725.1; -; Genomic_DNA. DR EMBL; UGCP01000002; STI88145.1; -; Genomic_DNA. DR EMBL; UGET01000004; STL74429.1; -; Genomic_DNA. DR EMBL; UGET01000004; STL76039.1; -; Genomic_DNA. DR EMBL; UGET01000004; STL82834.1; -; Genomic_DNA. DR EMBL; UGGI01000001; STQ33862.1; -; Genomic_DNA. DR EMBL; UINP01000018; SVF38503.1; -; Genomic_DNA. DR EMBL; UWXG01000003; VCZ14043.1; -; Genomic_DNA. DR EMBL; CABEEF010000003; VTQ21734.1; -; Genomic_DNA. DR RefSeq; WP_000019402.1; NZ_VTWC01000302.1. DR EnsemblBacteria; ANM84432; ANM84432; A8V37_18735. DR EnsemblBacteria; KME64525; KME64525; SM09_04106. DR EnsemblBacteria; KME65557; KME65557; SM09_03948. DR EnsemblBacteria; OCO59492; OCO59492; AN669_0209495. DR EnsemblBacteria; ODH14458; ODH14458; A6804_26935. DR EnsemblBacteria; ODH21372; ODH21372; A6803_26395. DR PATRIC; fig|562.7083.peg.4877; -. DR Proteomes; UP000184355; Unassembled WGS sequence. DR Proteomes; UP000184459; Unassembled WGS sequence. DR Proteomes; UP000233584; Chromosome. DR Proteomes; UP000254079; Unassembled WGS sequence. DR Proteomes; UP000254255; Unassembled WGS sequence. DR Proteomes; UP000254870; Unassembled WGS sequence. DR Proteomes; UP000254972; Unassembled WGS sequence. DR Proteomes; UP000255201; Unassembled WGS sequence. DR Proteomes; UP000255209; Unassembled WGS sequence. DR Proteomes; UP000259784; Unassembled WGS sequence. DR Proteomes; UP000272353; Unassembled WGS sequence. DR Proteomes; UP000290836; Unassembled WGS sequence. DR Proteomes; UP000292504; Unassembled WGS sequence. DR Proteomes; UP000324160; Plasmid unnamed3. DR Proteomes; UP000411984; Unassembled WGS sequence. DR GO; GO:0003677; F:DNA binding; IEA:InterPro. DR GO; GO:0004803; F:transposase activity; IEA:InterPro. DR GO; GO:0006313; P:transposition, DNA-mediated; IEA:InterPro. DR InterPro; IPR002559; Transposase_11. DR InterPro; IPR008490; Transposase_InsH_N. DR Pfam; PF01609; DDE_Tnp_1; 1. DR Pfam; PF05598; DUF772; 1. PE 3: Inferred from homology; KW DNA recombination {ECO:0000256|ARBA:ARBA00023172}; KW Plasmid {ECO:0000313|EMBL:AVU48516.1}; KW Transposable element {ECO:0000256|ARBA:ARBA00022464}; KW Transposition {ECO:0000256|ARBA:ARBA00022578}. FT DOMAIN 51..124 FT /note="DUF772" FT /evidence="ECO:0000259|Pfam:PF05598" FT DOMAIN 138..312 FT /note="DDE_Tnp_1" FT /evidence="ECO:0000259|Pfam:PF01609" SQ SEQUENCE 326 AA; 37823 MW; 9EFD70482D0324E6 CRC64; MSHQLTFADS EFSSKRRQTR KEIFLSRMEQ ILPWQNMVEV IEPFYPKAGN GRRPYPLETM LRIHCMQHWY NLSDGAMEDA LYEIASMRLF ARLSLDSALP DRTTIMNFRH LLEQHQLARQ LFKTINRWLA EAGVMMTQGT LVDATIIEAP SSTKNKEQQR DPEMHQTKKG NQWHFGMKAH IGVDAKSGLT HSLVTTAANE HDLNQLGNLL HGEEQFVSAD AGYQGAPQRE ELAEVDVDWL IAERPGKVRT LKQHPRKNKT AINIEYMKAS IRAKVEHPFR IIKRQFGFVK ARYKGLLKND NQLAMLFTLA NLFRADQMIR QWERSH //