ID A0A0H5SBI3_BRUMA Unreviewed; 395 AA. AC A0A0H5SBI3; DT 14-OCT-2015, integrated into UniProtKB/TrEMBL. DT 14-OCT-2015, sequence version 1. DT 27-MAR-2024, entry version 42. DE SubName: Full=BMA-ELT-1 {ECO:0000313|EMBL:CRZ25917.1}; DE SubName: Full=GATA-type domain-containing protein {ECO:0000313|WBParaSite:Bm6246.1}; GN Name=Bma-elt-1 {ECO:0000313|EMBL:CRZ25917.1, GN ECO:0000313|WBParaSite:Bm6246.1}; GN ORFNames=Bm6246 {ECO:0000313|WormBase:Bm6246}, BM_Bm6246 GN {ECO:0000313|EMBL:CRZ25917.1}; OS Brugia malayi (Filarial nematode worm). OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; OC Spirurina; Spiruromorpha; Filarioidea; Onchocercidae; Brugia. OX NCBI_TaxID=6279 {ECO:0000313|EMBL:CRZ25917.1}; RN [1] {ECO:0000313|EMBL:CRZ25917.1, ECO:0000313|Proteomes:UP000006672} RP NUCLEOTIDE SEQUENCE. RC STRAIN=FR3 {ECO:0000313|EMBL:CRZ25917.1, RC ECO:0000313|Proteomes:UP000006672}; RX PubMed=17885136; DOI=10.1126/science.1145406; RA Ghedin E., Wang S., Spiro D., Caler E., Zhao Q., Crabtree J., Allen J.E., RA Delcher A.L., Guiliano D.B., Miranda-Saavedra D., Angiuoli S.V., Creasy T., RA Amedeo P., Haas B., El-Sayed N.M., Wortman J.R., Feldblyum T., Tallon L., RA Schatz M., Shumway M., Koo H., Salzberg S.L., Schobel S., Pertea M., RA Pop M., White O., Barton G.J., Carlow C.K., Crawford M.J., Daub J., RA Dimmic M.W., Estes C.F., Foster J.M., Ganatra M., Gregory W.F., RA Johnson N.M., Jin J., Komuniecki R., Korf I., Kumar S., Laney S., Li B.W., RA Li W., Lindblom T.H., Lustigman S., Ma D., Maina C.V., Martin D.M., RA McCarter J.P., McReynolds L., Mitreva M., Nutman T.B., Parkinson J., RA Peregrin-Alvarez J.M., Poole C., Ren Q., Saunders L., Sluder A.E., RA Smith K., Stanke M., Unnasch T.R., Ware J., Wei A.D., Weil G., RA Williams D.J., Zhang Y., Williams S.A., Fraser-Liggett C., Slatko B., RA Blaxter M.L., Scott A.L.; RT "Draft genome of the filarial nematode parasite Brugia malayi."; RL Science 317:1756-1760(2007). RN [2] {ECO:0000313|EMBL:CRZ25917.1} RP NUCLEOTIDE SEQUENCE. RC STRAIN=FR3 {ECO:0000313|EMBL:CRZ25917.1}; RA Gao Y.W., Fan S.T., Sun H.T., Wang Z., Gao X.L., Li Y.G., Wang T.C., RA Zhang K., Xu W.W., Yu Z.J., Xia X.Z.; RL Submitted (DEC-2012) to the EMBL/GenBank/DDBJ databases. RN [3] {ECO:0000313|WBParaSite:Bm6246.1} RP IDENTIFICATION. RG WormBaseParasite; RL Submitted (DEC-2019) to UniProtKB. CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; LN857014; CRZ25917.1; -; Genomic_DNA. DR STRING; 6279.A0A0H5SBI3; -. DR EnsemblMetazoa; Bm6246.1; Bm6246.1; WBGene00226507. DR WBParaSite; Bm6246.1; Bm6246.1; WBGene00226507. DR WormBase; Bm6246; BM29907; WBGene00226507; -. DR OMA; EYKFQPN; -. DR OrthoDB; 2881962at2759; -. DR Proteomes; UP000006672; Unassembled WGS sequence. DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro. DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro. DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro. DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IEA:InterPro. DR CDD; cd00202; ZnF_GATA; 2. DR Gene3D; 3.30.50.10; Erythroid Transcription Factor GATA-1, subunit A; 2. DR InterPro; IPR039355; Transcription_factor_GATA. DR InterPro; IPR000679; Znf_GATA. DR InterPro; IPR013088; Znf_NHR/GATA. DR PANTHER; PTHR10071:SF338; BOX A-BINDING FACTOR-RELATED; 1. DR PANTHER; PTHR10071; TRANSCRIPTION FACTOR GATA FAMILY MEMBER; 1. DR Pfam; PF00320; GATA; 2. DR PRINTS; PR00619; GATAZNFINGER. DR SMART; SM00401; ZnF_GATA; 2. DR SUPFAM; SSF57716; Glucocorticoid receptor-like (DNA-binding domain); 2. DR PROSITE; PS00344; GATA_ZN_FINGER_1; 2. DR PROSITE; PS50114; GATA_ZN_FINGER_2; 2. PE 4: Predicted; KW Metal-binding {ECO:0000256|ARBA:ARBA00022723}; KW Nucleus {ECO:0000256|ARBA:ARBA00023242}; KW Reference proteome {ECO:0000313|Proteomes:UP000006672}; KW Transcription {ECO:0000256|ARBA:ARBA00023163}; KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}; KW Zinc {ECO:0000256|ARBA:ARBA00022833}; KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00094}. FT DOMAIN 226..281 FT /note="GATA-type" FT /evidence="ECO:0000259|PROSITE:PS50114" FT DOMAIN 280..333 FT /note="GATA-type" FT /evidence="ECO:0000259|PROSITE:PS50114" FT REGION 44..70 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT REGION 199..226 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" SQ SEQUENCE 395 AA; 43325 MW; 80032B1AC4D50F29 CRC64; MEYKFQPNNV GHPGDLYQPI QSIQETVIDA DQDVPVSDLS ALQMSSNTQS QDATNPAQND DSVFSPIKPS TFYSNSTQSG QLYYQGTPKV PDSYGTGGQF YPSLFFQTWP YSSTTANSSV TATIAGASPC SSNTAELSFT QPTTVITDPT QMLVAPNQTT TQNFFPQTYQ AYSTTDYYNP LHSANLLAAQ TRLTAPTVAC SSSGSASSRS STGVSGASRP KTRNFTSEGR ECVNCGAVQT PLWRRDGTGH YLCNACGLYH KMNGQNRPLV KPKKRQSAQK RTGIECVNCK TNNTTLWRRN SLGQPVCNAC GLYHKLHNIS RPISMKKDGI QTRNRKISTK NKNKKRGPSE GPFYDMLKPQ PNPYGDMKFH LPSAHAYIPA ATQTPYPAQF IFHAS //