ID A0A0H5S397_BRUMA Unreviewed; 347 AA. AC A0A0H5S397; DT 14-OCT-2015, integrated into UniProtKB/TrEMBL. DT 14-OCT-2015, sequence version 1. DT 16-OCT-2019, entry version 27. DE SubName: Full=BMA-MCU-1 {ECO:0000313|EMBL:CRZ22680.1, ECO:0000313|WBParaSite:Bm4745}; DE SubName: Full=Chromosome 10 open reading frame 42, putative {ECO:0000313|EMBL:VIO87616.1}; GN Name=Bma-mcu-1 {ECO:0000313|EMBL:CRZ22680.1}; GN ORFNames=BM_BM4745 {ECO:0000313|EMBL:VIO87616.1}, BM_Bm4745 GN {ECO:0000313|EMBL:CRZ22680.1}; OS Brugia malayi (Filarial nematode worm). OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; OC Spirurina; Spiruromorpha; Filarioidea; Onchocercidae; Brugia. OX NCBI_TaxID=6279 {ECO:0000313|EMBL:CRZ22680.1}; RN [1] {ECO:0000313|EMBL:CRZ22680.1, ECO:0000313|Proteomes:UP000006672, ECO:0000313|WBParaSite:Bm4745} RP NUCLEOTIDE SEQUENCE. RC STRAIN=FR3 {ECO:0000313|EMBL:CRZ22680.1, RC ECO:0000313|Proteomes:UP000006672}; RX PubMed=17885136; DOI=10.1126/science.1145406; RA Ghedin E., Wang S., Spiro D., Caler E., Zhao Q., Crabtree J., RA Allen J.E., Delcher A.L., Guiliano D.B., Miranda-Saavedra D., RA Angiuoli S.V., Creasy T., Amedeo P., Haas B., El-Sayed N.M., RA Wortman J.R., Feldblyum T., Tallon L., Schatz M., Shumway M., Koo H., RA Salzberg S.L., Schobel S., Pertea M., Pop M., White O., Barton G.J., RA Carlow C.K., Crawford M.J., Daub J., Dimmic M.W., Estes C.F., RA Foster J.M., Ganatra M., Gregory W.F., Johnson N.M., Jin J., RA Komuniecki R., Korf I., Kumar S., Laney S., Li B.W., Li W., RA Lindblom T.H., Lustigman S., Ma D., Maina C.V., Martin D.M., RA McCarter J.P., McReynolds L., Mitreva M., Nutman T.B., Parkinson J., RA Peregrin-Alvarez J.M., Poole C., Ren Q., Saunders L., Sluder A.E., RA Smith K., Stanke M., Unnasch T.R., Ware J., Wei A.D., Weil G., RA Williams D.J., Zhang Y., Williams S.A., Fraser-Liggett C., Slatko B., RA Blaxter M.L., Scott A.L.; RT "Draft genome of the filarial nematode parasite Brugia malayi."; RL Science 317:1756-1760(2007). RN [2] {ECO:0000313|EMBL:CRZ22680.1} RP NUCLEOTIDE SEQUENCE. RC STRAIN=FR3 {ECO:0000313|EMBL:CRZ22680.1}; RA Gao Y.W., Fan S.T., Sun H.T., Wang Z., Gao X.L., Li Y.G., Wang T.C., RA Zhang K., Xu W.W., Yu Z.J., Xia X.Z.; RL Submitted (DEC-2012) to the EMBL/GenBank/DDBJ databases. RN [3] {ECO:0000313|WBParaSite:Bm4745} RP IDENTIFICATION. RG WormBaseParasite; RL Submitted (SEP-2015) to UniProtKB. RN [4] {ECO:0000313|EMBL:VIO87616.1} RP NUCLEOTIDE SEQUENCE. RC STRAIN=FR3 {ECO:0000313|EMBL:VIO87616.1}; RA Howe K., Paulini M., Williams G.; RL Submitted (APR-2019) to the EMBL/GenBank/DDBJ databases. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; LN856618; CRZ22680.1; -; Genomic_DNA. DR EMBL; CAAKNF010000196; VIO87616.1; -; Genomic_DNA. DR EnsemblMetazoa; Bm4745; Bm4745; WBGene00225006. DR WBParaSite; Bm4745; Bm4745; WBGene00225006. DR OMA; CIEEHQL; -. DR Proteomes; UP000006672; Unassembled WGS sequence. DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW. DR GO; GO:0005739; C:mitochondrion; IEA:GOC. DR GO; GO:0042802; F:identical protein binding; IEA:EnsemblMetazoa. DR GO; GO:0036444; P:calcium import into the mitochondrion; IEA:EnsemblMetazoa. DR GO; GO:0051560; P:mitochondrial calcium ion homeostasis; IEA:EnsemblMetazoa. DR GO; GO:0051260; P:protein homooligomerization; IEA:EnsemblMetazoa. DR GO; GO:1903426; P:regulation of reactive oxygen species biosynthetic process; IEA:EnsemblMetazoa. DR GO; GO:0061041; P:regulation of wound healing; IEA:EnsemblMetazoa. DR InterPro; IPR006769; MCU_C. DR InterPro; IPR039055; MCU_fam. DR PANTHER; PTHR13462; PTHR13462; 1. DR Pfam; PF04678; MCU; 1. PE 4: Predicted; KW Complete proteome {ECO:0000313|Proteomes:UP000006672}; KW Membrane {ECO:0000256|SAM:Phobius}; KW Reference proteome {ECO:0000313|Proteomes:UP000006672}; KW Transmembrane {ECO:0000256|SAM:Phobius}; KW Transmembrane helix {ECO:0000256|SAM:Phobius}. FT TRANSMEM 215 234 Helical. {ECO:0000256|SAM:Phobius}. FT TRANSMEM 246 264 Helical. {ECO:0000256|SAM:Phobius}. FT DOMAIN 91 300 MCU. {ECO:0000259|Pfam:PF04678}. SQ SEQUENCE 347 AA; 40613 MW; 1BE8D3CF29BCA063 CRC64; MRCRWYSITG LLQQRQQHLQ IQLSTCYINL NNMHHLRRCS NDTTRGNLHI WCQSGLPLLE VPLPSRREIC QFTLKPISDT VSRFCKNIEC EDKGIEIVYV YSTSGNRIAG STLLKHLLLR GNFRLRINDF IYTVEVPSSK DVIANIMADG DVMQKFDGLR STIAPLYSIM NVEVYKAFQE RLLIEEYENV KAELKPLIQA KFKFDEFCRK RAQRILWLTL AAMGFQAGFL ARLTWWDYSW DVMEPITYFA THATLIASFA YYLYTNQYYN HNDHKKRAIS LYFHKKAAKS NFDISRFNEL QNVASSIKHD LKKLRDPLYQ HLPTARLASL LQESGKVQPR SFTKERS //