ID A0A0H5AZB2_9VIRU Unreviewed; 1401 AA. AC A0A0H5AZB2; DT 14-OCT-2015, integrated into UniProtKB/TrEMBL. DT 14-OCT-2015, sequence version 1. DT 08-NOV-2023, entry version 24. DE RecName: Full=Envelopment polyprotein {ECO:0000256|ARBA:ARBA00015294}; DE AltName: Full=M polyprotein {ECO:0000256|ARBA:ARBA00031199}; GN Name=M {ECO:0000313|EMBL:BAR94030.1}; OS Akabane virus. OC Viruses; Riboviria; Orthornavirae; Negarnaviricota; Polyploviricotina; OC Ellioviricetes; Bunyavirales; Peribunyaviridae; Orthobunyavirus; OC Orthobunyavirus akabaneense. OX NCBI_TaxID=70566 {ECO:0000313|EMBL:BAR94030.1, ECO:0000313|Proteomes:UP000155980}; RN [1] {ECO:0000313|EMBL:BAR94030.1, ECO:0000313|Proteomes:UP000155980} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=TS-C2 {ECO:0000313|EMBL:BAR94030.1}; RA Uema A., Sugiura K., Bangphoomi N., Shioda C., Uchida K., Kato K., Haga T., RA Murakami S., Horimoto T., Akashi H.; RT "Efficacy and safety of a recombinant Akabane vaccine candidate in a RT pregnant goat model."; RL Submitted (JUN-2014) to the EMBL/GenBank/DDBJ databases. CC -!- SUBCELLULAR LOCATION: Host Golgi apparatus membrane CC {ECO:0000256|ARBA:ARBA00004252}; Multi-pass membrane protein CC {ECO:0000256|ARBA:ARBA00004252}. Membrane CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein CC {ECO:0000256|ARBA:ARBA00004141}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AB968526; BAR94030.1; -; Viral_cRNA. DR Proteomes; UP000155980; Genome. DR GO; GO:0044178; C:host cell Golgi membrane; IEA:UniProtKB-SubCell. DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell. DR GO; GO:0019048; P:modulation by virus of host process; IEA:InterPro. DR InterPro; IPR005167; Bunya_G1. DR InterPro; IPR005168; Bunya_G2. DR InterPro; IPR026400; Bunya_nonstruc_pro_NSm. DR NCBIfam; TIGR04210; bunya_NSm; 1. DR Pfam; PF03557; Bunya_G1; 1. DR Pfam; PF03563; Bunya_G2; 1. PE 4: Predicted; KW Host Golgi apparatus {ECO:0000256|ARBA:ARBA00022812}; KW Membrane {ECO:0000256|SAM:Phobius}; Signal {ECO:0000256|ARBA:ARBA00022729}; KW Transmembrane {ECO:0000256|SAM:Phobius}; KW Transmembrane helix {ECO:0000256|SAM:Phobius}. FT TRANSMEM 213..230 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT TRANSMEM 236..253 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT TRANSMEM 319..338 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT TRANSMEM 365..389 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT TRANSMEM 446..464 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT TRANSMEM 1355..1373 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT DOMAIN 27..309 FT /note="Bunyavirus glycoprotein G2" FT /evidence="ECO:0000259|Pfam:PF03563" FT DOMAIN 531..1340 FT /note="Bunyavirus glycoprotein G1" FT /evidence="ECO:0000259|Pfam:PF03557" SQ SEQUENCE 1401 AA; 157982 MW; 34CAACE59AA98A5B CRC64; MIITILNVLT LVVTVTAMHP RNTNGGRCFY GGDMFRQINS TSPMSEICVR DDISLVKSIG YHKLAANREV IESSMSYYRL YYVKNWFECN PVQDILGTFM VFDVNHEGIL APKTYACRAT CSISLERDTG NVVLESPALN HYTIHGTTIK NGWFKTKVSI DLDNTCEDLH ITCGHRTLNV HACFRQHKSC IRYFKGSILP EVMIESICTN AELILLCCFS AISCFVAIIL TKTYLVYLLI PIFYPFVKLY GLLLQRFCKQ CKNCLLPIHP FSPCPTTCIC GMVYNSTEAL KVHRKCLNCT GYKTLTKTRY LCKKRLPNMV LATISTVLFF TFITPITAEC YNYTSLPADF QAAIDKNNSC TREQLIMIIL TILCIASIIM PISAVHLYIQ IYYVFCAYCG IVHEKKGLIL LDNFTSHCLT CICRDKSIHR ANNNRVTPMK YKTAKYTNLL CIIFLIIIAV TPAFSACIQE EEIETIDDAA MCIGLYQNIT QPKEYNTFVK ELSSTLSSHE IEFLLPAVKP SFDYLITKSS TSKDLHSATI HEFIAANLYP NNFKKHLASA GPGSIQWRTY IQNNNLHLCN DHVVKMICRC VIKQEECSST KVDDGEQIAQ YYKRNKEFYK ADLGILYTVI SRAIPGLVGN LLRQVLKSQK YGESLHVLNK IKKDVSKNNQ LNGIVEFLIH INSQNITEEV RELRIRPDLS IRGSKFTDKN PGIPDIKECQ TPLFITCTGK RFRSLMKQYI ACSNGGVKLY QRPNKPLALV GNKLCIGDKY CMIAFDPMVI DENIQKLDCY SLAATDQSDG MLKPERSIRL LKTGECKIAG ALSRIAVSIN QKNYKYSTIV HKKSDLVDEY CLSPNCDLDC YPYYPANLVD CSWSESTHST LNQKVISHTD IESFISSVKL SLHNDLIQHH FRPLSNMPHV KPNFKSINVQ GTISGGKIQD SYITFSIPLM TGLSQGFTLQ DHKGNTLFDI IAYVKSARVI ATYNHEYKTG PTVSINVQHN EQCTGSCPSS IPKKDNWLTF SREHTSTWGC EEWGCLAIGT GCVYGSCQDV IREEATVISR VNNEQLEVEF CVSEPTSTMC NTINVLEPVL GEHMQFEVHS VQTNLLPEVA LIKNRRVYKG SINKKGVFNP QCGSVQSFDG KLYGIGNPKF DYICHALSRK DIVVRKCYEN HYYSCATLKE AVEIKPNITN SKTMLYNDNA LLGSASIKIM LGDLIYQQTS VQEKDIRGHA TCGGCTDCFN DVACKISMTS NGVYQCPIVS SCDSYINNVY INEGTNDVNL KFRCLKAEIK ISICGKEIPV KSEIIKDTKK LDLASADQTS YIKEFDKKCA AWLCRAYNEG IGFVLEPLWN ELSLWGKYVL LALAIIISVL ILVKVIRPLA RYVVAVLKEN DKVYKLENKL K //