ID A0A0H4MA49_HUMAN Unreviewed; 185 AA. AC A0A0H4MA49; DT 14-OCT-2015, integrated into UniProtKB/TrEMBL. DT 14-OCT-2015, sequence version 1. DT 24-JUL-2024, entry version 17. DE SubName: Full=MHC class I antigen {ECO:0000313|EMBL:AKP20295.1}; DE Flags: Fragment; GN Name=HLA-G {ECO:0000313|EMBL:AKP20295.1}; OS Homo sapiens (Human). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; OC Homo. OX NCBI_TaxID=9606 {ECO:0000313|EMBL:AKP20295.1}; RN [1] {ECO:0000313|EMBL:AKP20295.1} RP NUCLEOTIDE SEQUENCE. RX PubMed=26134300; DOI=10.1016/j.meegid.2015.06.027; RA Alves B.M., Prellwitz I.M., Siqueira J.D., Meyrelles A.R., Bergmann A., RA Seuanez H.N., Machado E.S., Soares M.A., Soares E.A.; RT "The effect of human leukocyte antigen G alleles on human papillomavirus RT infection and persistence in a cohort of HIV-positive pregnant women from RT Brazil."; RL Infect. Genet. Evol. 34:339-343(2015). CC -!- SIMILARITY: Belongs to the MHC class I family. CC {ECO:0000256|RuleBase:RU004439}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; KP322267; AKP20295.1; -; Genomic_DNA. DR AlphaFoldDB; A0A0H4MA49; -. DR SMR; A0A0H4MA49; -. DR ChiTaRS; HLA-G; human. DR GO; GO:0009897; C:external side of plasma membrane; IEA:TreeGrafter. DR GO; GO:0005615; C:extracellular space; IEA:TreeGrafter. DR GO; GO:0042605; F:peptide antigen binding; IEA:TreeGrafter. DR GO; GO:0005102; F:signaling receptor binding; IEA:TreeGrafter. DR GO; GO:0002486; P:antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent; IEA:TreeGrafter. DR GO; GO:0002476; P:antigen processing and presentation of endogenous peptide antigen via MHC class Ib; IEA:TreeGrafter. DR GO; GO:0006955; P:immune response; IEA:TreeGrafter. DR GO; GO:0001916; P:positive regulation of T cell mediated cytotoxicity; IEA:TreeGrafter. DR Gene3D; 3.30.500.10; MHC class I-like antigen recognition-like; 1. DR InterPro; IPR050208; MHC_class-I_related. DR InterPro; IPR011161; MHC_I-like_Ag-recog. DR InterPro; IPR037055; MHC_I-like_Ag-recog_sf. DR InterPro; IPR011162; MHC_I/II-like_Ag-recog. DR InterPro; IPR001039; MHC_I_a_a1/a2. DR PANTHER; PTHR16675:SF169; HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, ALPHA CHAIN G; 1. DR PANTHER; PTHR16675; MHC CLASS I-RELATED; 1. DR Pfam; PF00129; MHC_I; 1. DR PRINTS; PR01638; MHCCLASSI. DR SUPFAM; SSF54452; MHC antigen-recognition domain; 1. PE 3: Inferred from homology; KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180}; KW Signal {ECO:0000256|ARBA:ARBA00022729}. FT DOMAIN 1..127 FT /note="MHC class I-like antigen recognition-like" FT /evidence="ECO:0000259|Pfam:PF00129" FT NON_TER 1 FT /evidence="ECO:0000313|EMBL:AKP20295.1" SQ SEQUENCE 185 AA; 21352 MW; D39C928E177D1B4D CRC64; SMRYFSAAVS RPGRGEPRFI AMGYVDDTQF VRFDSDSACP RMEPRAPWVE QEGPEYWEEE TRNTKAHAQT DRMNLQTLRG YYNQSEASSH TLQWMIGCDL GSDGRLLRGY EQYAYDGKDY LALNEDCAPG PQRTLRLRSP SASVRRPMWL NKGEPTWRAR AWSGSTDTWR TGRRCCSART PPRHT //