ID A0A0G3HIX5_9CORY Unreviewed; 544 AA. AC A0A0G3HIX5; DT 16-SEP-2015, integrated into UniProtKB/TrEMBL. DT 16-SEP-2015, sequence version 1. DT 02-DEC-2020, entry version 22. DE RecName: Full=60 kDa chaperonin {ECO:0000256|HAMAP-Rule:MF_00600, ECO:0000256|RuleBase:RU000419}; DE AltName: Full=GroEL protein {ECO:0000256|HAMAP-Rule:MF_00600}; DE AltName: Full=Protein Cpn60 {ECO:0000256|HAMAP-Rule:MF_00600}; GN Name=groL2 {ECO:0000313|EMBL:AKK11893.1}; GN Synonyms=groEL {ECO:0000256|HAMAP-Rule:MF_00600}, groL GN {ECO:0000256|HAMAP-Rule:MF_00600}; GN ORFNames=CUTER_09625 {ECO:0000313|EMBL:AKK11893.1}; OS Corynebacterium uterequi. OC Bacteria; Actinobacteria; Corynebacteriales; Corynebacteriaceae; OC Corynebacterium. OX NCBI_TaxID=1072256 {ECO:0000313|EMBL:AKK11893.1, ECO:0000313|Proteomes:UP000035548}; RN [1] {ECO:0000313|EMBL:AKK11893.1, ECO:0000313|Proteomes:UP000035548} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=DSM 45634 {ECO:0000313|EMBL:AKK11893.1, RC ECO:0000313|Proteomes:UP000035548}; RX PubMed=26227590; RA Ruckert C., Kriete M., Jaenicke S., Winkler A., Tauch A.; RT "Virulence Factor Genes Detected in the Complete Genome Sequence of RT Corynebacterium uterequi DSM 45634, Isolated from the Uterus of a Maiden RT Mare."; RL Genome Announc. 3:e00783-15(2015). RN [2] {ECO:0000313|Proteomes:UP000035548} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=DSM 45634 {ECO:0000313|Proteomes:UP000035548}; RA Ruckert C., Albersmeier A., Winkler A., Tauch A.; RT "Complete genome sequence of Corynebacterium uterequi DSM 45634, isolated RT from the uterus of a maiden mare."; RL Submitted (MAY-2015) to the EMBL/GenBank/DDBJ databases. CC -!- FUNCTION: Prevents misfolding and promotes the refolding and proper CC assembly of unfolded polypeptides generated under stress conditions. CC {ECO:0000256|HAMAP-Rule:MF_00600, ECO:0000256|RuleBase:RU000419}. CC -!- SUBUNIT: Oligomer of 14 subunits composed of two stacked rings of 7 CC subunits. {ECO:0000256|HAMAP-Rule:MF_00600, CC ECO:0000256|RuleBase:RU000419}. CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00600}. CC -!- SIMILARITY: Belongs to the chaperonin (HSP60) family. CC {ECO:0000256|ARBA:ARBA00006607, ECO:0000256|HAMAP-Rule:MF_00600, CC ECO:0000256|RuleBase:RU000418}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; CP011546; AKK11893.1; -; Genomic_DNA. DR RefSeq; WP_047260211.1; NZ_CP011546.1. DR EnsemblBacteria; AKK11893; AKK11893; CUTER_09625. DR KEGG; cut:CUTER_09625; -. DR PATRIC; fig|1072256.5.peg.1896; -. DR OrthoDB; 265347at2; -. DR Proteomes; UP000035548; Chromosome. DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule. DR GO; GO:0051082; F:unfolded protein binding; IEA:UniProtKB-UniRule. DR GO; GO:0042026; P:protein refolding; IEA:UniProtKB-UniRule. DR CDD; cd03344; GroEL; 1. DR Gene3D; 1.10.560.10; -; 1. DR Gene3D; 3.30.260.10; -; 1. DR Gene3D; 3.50.7.10; -; 1. DR HAMAP; MF_00600; CH60; 1. DR InterPro; IPR018370; Chaperonin_Cpn60_CS. DR InterPro; IPR001844; Chaprnin_Cpn60. DR InterPro; IPR002423; Cpn60/TCP-1. DR InterPro; IPR027409; GroEL-like_apical_dom_sf. DR InterPro; IPR027413; GROEL-like_equatorial_sf. DR InterPro; IPR027410; TCP-1-like_intermed_sf. DR Pfam; PF00118; Cpn60_TCP1; 1. DR PRINTS; PR00298; CHAPERONIN60. DR SUPFAM; SSF48592; SSF48592; 1. DR SUPFAM; SSF52029; SSF52029; 1. DR SUPFAM; SSF54849; SSF54849; 1. DR TIGRFAMs; TIGR02348; GroEL; 1. DR PROSITE; PS00296; CHAPERONINS_CPN60; 1. PE 3: Inferred from homology; KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|HAMAP- KW Rule:MF_00600}; KW Chaperone {ECO:0000256|ARBA:ARBA00023186, ECO:0000256|HAMAP-Rule:MF_00600}; KW Coiled coil {ECO:0000256|SAM:Coils}; KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490, ECO:0000256|HAMAP-Rule:MF_00600}; KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|HAMAP- KW Rule:MF_00600}; Reference proteome {ECO:0000313|Proteomes:UP000035548}. FT REGION 525..544 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COILED 349..369 FT /evidence="ECO:0000256|SAM:Coils" FT COILED 392..412 FT /evidence="ECO:0000256|SAM:Coils" SQ SEQUENCE 544 AA; 57153 MW; 5B3124EA78DA6C25 CRC64; MSKIIAFDEE ARRGLERGLN TLADAVKVTL GPKGRNVVLE KSWGAPTITN DGVTIAKEIE LEDPYEKIGA ELVKEVAKKT DDVAGDGTTT ATVLAQALVS EGLRNVAAGS NPMGIKRGIE AAVAKVNDEI LATAKEVETE EEIAQTAGIS AADPEIGKQI ARAMYAVGNG AVNKDSVITV EESNTFGVDL EVTEGMRFDK GYISGYFATD MERQEAVLED PYILLVSAKI SNIKDLLPLL EQVMQSGKPL LIIAEDVEGE ALSTLVVNKI RGTFKSVAVK APGFGDRRKA QLQDMAILTG GQVISEEVGL SLETATVDLL GTARKVVVTK DETTIVQGAG SPEQIEGRVK QIRAEIENSD SEYDREKLQE RLAKLAGGVA VIKVGAATEV ELKERKLRIE DAVRNAKAAV EEGIVAGGGV ALLQAASVLD SLELEGDEAT GVKIVRDSLS APLKQIAFNA GLEPGVVADK VAHLPTGEGL NAATGEYVDM MKAGINDPAK VTRSALQNAA SIAALFLTTE AVVADKPQPA GSGPSPEDMA GMGM //