ID A0A0G2JGL0_MOUSE Unreviewed; 148 AA. AC A0A0G2JGL0; DT 22-JUL-2015, integrated into UniProtKB/TrEMBL. DT 22-JUL-2015, sequence version 1. DT 02-JUN-2021, entry version 33. DE SubName: Full=Ubiquitin-conjugating enzyme E2 D3 {ECO:0000313|Ensembl:ENSMUSP00000143606}; GN Name=Ube2d3 {ECO:0000313|Ensembl:ENSMUSP00000143606, GN ECO:0000313|MGI:MGI:1913355}; OS Mus musculus (Mouse). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; OC Murinae; Mus; Mus. OX NCBI_TaxID=10090 {ECO:0000313|Ensembl:ENSMUSP00000143606, ECO:0000313|Proteomes:UP000000589}; RN [1] {ECO:0000313|Ensembl:ENSMUSP00000143606, ECO:0000313|Proteomes:UP000000589} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000143606, RC ECO:0000313|Proteomes:UP000000589}; RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112; RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., RA Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y., RA Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S., RA Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R., RA Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K., RA Eichler E.E., Ponting C.P.; RT "Lineage-specific biology revealed by a finished genome assembly of the RT mouse."; RL PLoS Biol. 7:E1000112-E1000112(2009). RN [2] {ECO:0000313|Ensembl:ENSMUSP00000143606} RP IDENTIFICATION. RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000143606}; RG Ensembl; RL Submitted (JUN-2015) to UniProtKB. CC -!- SIMILARITY: Belongs to the ubiquitin-conjugating enzyme family. CC {ECO:0000256|RuleBase:RU362109}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR SMR; A0A0G2JGL0; -. DR jPOST; A0A0G2JGL0; -. DR ProteomicsDB; 357873; -. DR Antibodypedia; 26052; 219 antibodies. DR Ensembl; ENSMUST00000197134; ENSMUSP00000143606; ENSMUSG00000078578. DR MGI; MGI:1913355; Ube2d3. DR GeneTree; ENSGT00940000153169; -. DR OMA; FKPPKVH; -. DR ChiTaRS; Ube2d3; mouse. DR Proteomes; UP000000589; Chromosome 3. DR Bgee; ENSMUSG00000078578; Expressed in undifferentiated genital tubercle and 311 other tissues. DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule. DR GO; GO:0004842; F:ubiquitin-protein transferase activity; IEA:Ensembl. DR GO; GO:0071276; P:cellular response to cadmium ion; IEA:Ensembl. DR GO; GO:0071288; P:cellular response to mercury ion; IEA:Ensembl. DR GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:Ensembl. DR CDD; cd00195; UBCc; 1. DR Gene3D; 3.10.110.10; -; 1. DR InterPro; IPR000608; UBQ-conjugat_E2. DR InterPro; IPR023313; UBQ-conjugating_AS. DR InterPro; IPR016135; UBQ-conjugating_enzyme/RWD. DR Pfam; PF00179; UQ_con; 1. DR SUPFAM; SSF54495; SSF54495; 1. DR PROSITE; PS00183; UBIQUITIN_CONJUGAT_1; 1. DR PROSITE; PS50127; UBIQUITIN_CONJUGAT_2; 1. PE 1: Evidence at protein level; KW ATP-binding {ECO:0000256|RuleBase:RU362109}; KW Nucleotide-binding {ECO:0000256|RuleBase:RU362109}; KW Proteomics identification {ECO:0007829|EPD:A0A0G2JGL0, KW ECO:0007829|MaxQB:A0A0G2JGL0}; KW Reference proteome {ECO:0000313|Proteomes:UP000000589}; KW Transferase {ECO:0000256|ARBA:ARBA00022679}; KW Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786, KW ECO:0000256|RuleBase:RU362109}. FT DOMAIN 4..136 FT /note="UBC core" FT /evidence="ECO:0000259|PROSITE:PS50127" FT ACT_SITE 85 FT /note="Glycyl thioester intermediate" FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10133" SQ SEQUENCE 148 AA; 16785 MW; E73DC194DB6D4EFE CRC64; MALKRINKEL SDLARDPPAQ CSAGPVGDDM FHWQATIMGP NDSPYQGGVF FLTIHFPTDY PFKPPKVAFT TRIYHPNINS NGSICLDILR SQWSPALTIS KVLLSICSLL CDPNPDDPLV PEIARIYKTD RDKYNRLARE WTEKYAML //