ID A0A0G2JEP0_MOUSE Unreviewed; 568 AA. AC A0A0G2JEP0; DT 22-JUL-2015, integrated into UniProtKB/TrEMBL. DT 22-JUL-2015, sequence version 1. DT 28-FEB-2018, entry version 19. DE SubName: Full=Fragile X mental retardation syndrome-related protein 1 {ECO:0000313|Ensembl:ENSMUSP00000142847}; GN Name=Fxr1 {ECO:0000313|Ensembl:ENSMUSP00000142847, GN ECO:0000313|MGI:MGI:104860}; OS Mus musculus (Mouse). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; OC Muroidea; Muridae; Murinae; Mus; Mus. OX NCBI_TaxID=10090 {ECO:0000313|Ensembl:ENSMUSP00000142847, ECO:0000313|Proteomes:UP000000589}; RN [1] {ECO:0000213|PubMed:15592455} RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]. RX PubMed=15592455; DOI=10.1038/nbt1046; RA Rush J., Moritz A., Lee K.A., Guo A., Goss V.L., Spek E.J., Zhang H., RA Zha X.M., Polakiewicz R.D., Comb M.J.; RT "Immunoaffinity profiling of tyrosine phosphorylation in cancer RT cells."; RL Nat. Biotechnol. 23:94-101(2005). RN [2] {ECO:0000213|PubMed:16452087} RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]. RX PubMed=16452087; DOI=10.1074/mcp.T500041-MCP200; RA Trinidad J.C., Specht C.G., Thalhammer A., Schoepfer R., RA Burlingame A.L.; RT "Comprehensive identification of phosphorylation sites in postsynaptic RT density preparations."; RL Mol. Cell. Proteomics 5:914-922(2006). RN [3] {ECO:0000213|PubMed:17947660} RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]. RX PubMed=17947660; RA Cao L., Yu K., Banh C., Nguyen V., Ritz A., Raphael B.J., Kawakami Y., RA Kawakami T., Salomon A.R.; RT "Quantitative time-resolved phosphoproteomic analysis of mast cell RT signaling."; RL J. Immunol. 179:5864-5876(2007). RN [4] {ECO:0000213|PubMed:17242355} RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]. RX PubMed=17242355; DOI=10.1073/pnas.0609836104; RA Villen J., Beausoleil S.A., Gerber S.A., Gygi S.P.; RT "Large-scale phosphorylation analysis of mouse liver."; RL Proc. Natl. Acad. Sci. U.S.A. 104:1488-1493(2007). RN [5] {ECO:0000313|Ensembl:ENSMUSP00000142847, ECO:0000313|Proteomes:UP000000589} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000142847, RC ECO:0000313|Proteomes:UP000000589}; RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112; RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., RA She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., RA Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., RA Zhou S., Teague B., Potamousis K., Churas C., Place M., Herschleb J., RA Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., RA Lindblad-Toh K., Eichler E.E., Ponting C.P.; RT "Lineage-specific biology revealed by a finished genome assembly of RT the mouse."; RL PLoS Biol. 7:E1000112-E1000112(2009). RN [6] {ECO:0000213|PubMed:21183079} RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]. RX PubMed=21183079; DOI=10.1016/j.cell.2010.12.001; RA Huttlin E.L., Jedrychowski M.P., Elias J.E., Goswami T., Rad R., RA Beausoleil S.A., Villen J., Haas W., Sowa M.E., Gygi S.P.; RT "A tissue-specific atlas of mouse protein phosphorylation and RT expression."; RL Cell 143:1174-1189(2010). RN [7] {ECO:0000313|Ensembl:ENSMUSP00000142847} RP IDENTIFICATION. RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000142847}; RG Ensembl; RL Submitted (JUN-2015) to UniProtKB. CC -!- CAUTION: The sequence shown here is derived from an Ensembl CC automatic analysis pipeline and should be considered as CC preliminary data. {ECO:0000313|Ensembl:ENSMUSP00000142847}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AC068294; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; AC115078; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR RefSeq; XP_006535465.1; XM_006535402.1. DR UniGene; Mm.259021; -. DR SMR; A0A0G2JEP0; -. DR Ensembl; ENSMUST00000198051; ENSMUSP00000142847; ENSMUSG00000027680. DR GeneID; 14359; -. DR CTD; 8087; -. DR MGI; MGI:104860; Fxr1. DR GeneTree; ENSGT00390000017033; -. DR Proteomes; UP000000589; Chromosome 3. DR Bgee; ENSMUSG00000027680; -. DR ExpressionAtlas; A0A0G2JEP0; baseline and differential. DR GO; GO:0030424; C:axon; IEA:Ensembl. DR GO; GO:0043034; C:costamere; IEA:Ensembl. DR GO; GO:0005829; C:cytosol; IEA:Ensembl. DR GO; GO:0043197; C:dendritic spine; IEA:Ensembl. DR GO; GO:0005634; C:nucleus; IEA:Ensembl. DR GO; GO:0048471; C:perinuclear region of cytoplasm; IEA:Ensembl. DR GO; GO:0005844; C:polysome; IEA:Ensembl. DR GO; GO:0035770; C:ribonucleoprotein granule; IEA:Ensembl. DR GO; GO:0002151; F:G-quadruplex RNA binding; IEA:Ensembl. DR GO; GO:0003730; F:mRNA 3'-UTR binding; IEA:Ensembl. DR GO; GO:0046982; F:protein heterodimerization activity; IEA:Ensembl. DR GO; GO:0042803; F:protein homodimerization activity; IEA:Ensembl. DR GO; GO:0033592; F:RNA strand annealing activity; IEA:Ensembl. DR GO; GO:0007517; P:muscle organ development; IEA:Ensembl. DR GO; GO:0017148; P:negative regulation of translation; IEA:Ensembl. DR GO; GO:2000637; P:positive regulation of gene silencing by miRNA; IEA:Ensembl. DR Gene3D; 3.30.1370.10; -; 2. DR InterPro; IPR008395; Agenet-like_dom. DR InterPro; IPR022034; FXMRP1_C_core. DR InterPro; IPR032172; FXR_C1. DR InterPro; IPR004087; KH_dom. DR InterPro; IPR004088; KH_dom_type_1. DR InterPro; IPR036612; KH_dom_type_1_sf. DR Pfam; PF05641; Agenet; 2. DR Pfam; PF12235; FXMRP1_C_core; 1. DR Pfam; PF16096; FXR_C1; 1. DR Pfam; PF00013; KH_1; 2. DR SMART; SM00322; KH; 2. DR SUPFAM; SSF54791; SSF54791; 2. DR PROSITE; PS51641; AGENET_LIKE; 2. PE 1: Evidence at protein level; KW Complete proteome {ECO:0000313|Proteomes:UP000000589}; KW Proteomics identification {ECO:0000213|EPD:A0A0G2JEP0, KW ECO:0000213|MaxQB:A0A0G2JEP0, ECO:0000213|PeptideAtlas:A0A0G2JEP0}; KW Reference proteome {ECO:0000313|Proteomes:UP000000589}. FT DOMAIN 4 50 Agenet-like. {ECO:0000259|PROSITE: FT PS51641}. FT DOMAIN 63 115 Agenet-like. {ECO:0000259|PROSITE: FT PS51641}. SQ SEQUENCE 568 AA; 63915 MW; 2087AA7D0C7AAFD6 CRC64; MAELTVEVRG SNGAFYKGFI KDVHEDSLTV VFENNWQPER QVPFNEVRLP PPPDIKKEIS EGDEVEVYSR ANDQEPCGWW LAKVRMMKGE FYVIEYAACD ATYNEIVTFE RLRPVNQNKT VKKNTFFKCT VDVPEDLREA CANENAHKDF KKAVGACRIF YHPETTQLMI LSASEATVKR VNILSDMHLR SIRTKLMLMS RNEEATKHLE CTKQLAAAFH EEFVVREDLM GLAIGTHGSN IQQARKVPGV TAIELDEDTG TFRIYGESAE AVKKARGFLE FVEDFIQVPR NLVGKVIGKN GKVIQEIVDK SGVVRVRIEG DNENKLPRED GMVPFVFVGT KESIGNVQVL LEYHIAYLKE VEQLRMERLQ IDEQLRQIGM GFRPSSTRGP EREKGYATDE STVSSVQGSR SYSGRGRGRR GPNYTSGYGT NSELSNPSET ESERKDELSD WSLAGEDDRE TRHQRDSRRR PGGRGRSVSG GRGRGGPRGG KSSISSVLKD PDSNPYSLLD NTESDQTADT DASESHHSTN RRRRSRRRRT DEDAVLMDGL TESDTASVNE NGLGKRCD //