ID A0A0E1M2A9_ECOLX Unreviewed; 210 AA. AC A0A0E1M2A9; DT 27-MAY-2015, integrated into UniProtKB/TrEMBL. DT 27-MAY-2015, sequence version 1. DT 12-OCT-2022, entry version 39. DE RecName: Full=cAMP-activated global transcriptional regulator CRP {ECO:0000256|ARBA:ARBA00015905}; DE AltName: Full=Catabolite activator protein {ECO:0000256|ARBA:ARBA00030901}; DE AltName: Full=Catabolite gene activator {ECO:0000256|ARBA:ARBA00032799}; DE AltName: Full=cAMP receptor protein {ECO:0000256|ARBA:ARBA00033082}; DE AltName: Full=cAMP regulatory protein {ECO:0000256|ARBA:ARBA00029868}; GN Name=crp {ECO:0000313|EMBL:AJF58166.1}; GN ORFNames=EC1303_c35040 {ECO:0000313|EMBL:AJF58166.1}; OS Escherichia coli 1303. OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; OC Enterobacteriaceae; Escherichia. OX NCBI_TaxID=745156 {ECO:0000313|EMBL:AJF58166.1, ECO:0000313|Proteomes:UP000031758}; RN [1] {ECO:0000313|EMBL:AJF58166.1, ECO:0000313|Proteomes:UP000031758} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=1303 {ECO:0000313|EMBL:AJF58166.1, RC ECO:0000313|Proteomes:UP000031758}; RA Leimbach A., Poehlein A., Daniel R., Dobrindt U.; RT "Complete genome sequences of Escherichia coli strains 1303 and ECC-1470 RT isolated from bovine mastitis."; RL Submitted (DEC-2014) to the EMBL/GenBank/DDBJ databases. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; CP009166; AJF58166.1; -; Genomic_DNA. DR RefSeq; WP_000242755.1; NZ_CP009166.1. DR SMR; A0A0E1M2A9; -. DR EnsemblBacteria; AJF58166; AJF58166; EC1303_c35040. DR GeneID; 67450219; -. DR GeneID; 72530068; -. DR HOGENOM; CLU_075053_3_5_6; -. DR Proteomes; UP000031758; Chromosome. DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW. DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro. DR CDD; cd00038; CAP_ED; 1. DR Gene3D; 1.10.10.10; -; 1. DR Gene3D; 2.60.120.10; -; 1. DR InterPro; IPR018488; cNMP-bd_CS. DR InterPro; IPR000595; cNMP-bd_dom. DR InterPro; IPR018490; cNMP-bd_dom_sf. DR InterPro; IPR012318; HTH_CRP. DR InterPro; IPR014710; RmlC-like_jellyroll. DR InterPro; IPR018335; Tscrpt_reg_HTH_Crp-type_CS. DR InterPro; IPR036388; WH-like_DNA-bd_sf. DR InterPro; IPR036390; WH_DNA-bd_sf. DR Pfam; PF00027; cNMP_binding; 1. DR Pfam; PF13545; HTH_Crp_2; 1. DR PRINTS; PR00034; HTHCRP. DR SMART; SM00100; cNMP; 1. DR SMART; SM00419; HTH_CRP; 1. DR SUPFAM; SSF46785; SSF46785; 1. DR SUPFAM; SSF51206; SSF51206; 1. DR PROSITE; PS00888; CNMP_BINDING_1; 1. DR PROSITE; PS00889; CNMP_BINDING_2; 1. DR PROSITE; PS50042; CNMP_BINDING_3; 1. DR PROSITE; PS00042; HTH_CRP_1; 1. DR PROSITE; PS51063; HTH_CRP_2; 1. PE 4: Predicted; KW Acetylation {ECO:0000256|ARBA:ARBA00022990}; KW DNA-binding {ECO:0000256|ARBA:ARBA00023125}. FT DOMAIN 24..124 FT /note="Cyclic nucleotide-binding" FT /evidence="ECO:0000259|PROSITE:PS50042" FT DOMAIN 138..210 FT /note="HTH crp-type" FT /evidence="ECO:0000259|PROSITE:PS51063" SQ SEQUENCE 210 AA; 23640 MW; DCBC24FA46C61B3D CRC64; MVLGKPQTDP TLEWFLSHCH IHKYPSKSTL IHQGEKAETL YYIVKGSVAV LIKDEEGKEM ILSYLNQGDF IGELGLFEEG QERSAWVRAK TACEVAEISY KKFRQLIQVN PDILMRLSAQ MARRLQVTSE KVGNLAFLDV TGRIAQTLLN LAKQPDAMTH PDGMQIKITR QEIGQIVGCS RETVGRILKM LEDQNLISAH GKTIVVYGTR //