ID A0A0D6I812_SALTM Unreviewed; 815 AA. AC A0A0D6I812; DT 27-MAY-2015, integrated into UniProtKB/TrEMBL. DT 27-MAY-2015, sequence version 1. DT 16-MAR-2016, entry version 9. DE RecName: Full=Alpha-1,4 glucan phosphorylase {ECO:0000256|RuleBase:RU000587}; DE EC=2.4.1.1 {ECO:0000256|RuleBase:RU000587}; GN Name=glgP {ECO:0000313|EMBL:CKH84803.1}; GN ORFNames=ABT68_22430 {ECO:0000313|EMBL:KMM48493.1}, ABT69_22320 GN {ECO:0000313|EMBL:KLT11990.1}, ABT70_22325 GN {ECO:0000313|EMBL:KMJ17912.1}, ABT73_17995 GN {ECO:0000313|EMBL:KMJ25351.1}, ABT74_22375 GN {ECO:0000313|EMBL:KMJ36185.1}, ABT75_18060 GN {ECO:0000313|EMBL:KMJ33273.1}, ABT76_22245 GN {ECO:0000313|EMBL:KMJ34320.1}, ABT77_22405 GN {ECO:0000313|EMBL:KMJ19010.1}, ABT80_22285 GN {ECO:0000313|EMBL:KLT25918.1}, ABT82_22390 GN {ECO:0000313|EMBL:KLT24717.1}, ABT85_22345 GN {ECO:0000313|EMBL:KLT23827.1}, ABT86_22365 GN {ECO:0000313|EMBL:KLT35658.1}, ABT87_22320 GN {ECO:0000313|EMBL:KMJ77482.1}, ABT89_22305 GN {ECO:0000313|EMBL:KMJ74619.1}, ABT91_22320 GN {ECO:0000313|EMBL:KMJ61402.1}, AOX79_04000 GN {ECO:0000313|EMBL:KTA23522.1}, DD38_18685 GN {ECO:0000313|EMBL:KTW47802.1}, DD42_05155 GN {ECO:0000313|EMBL:KTW68212.1}, DD43_09975 GN {ECO:0000313|EMBL:KTW71700.1}, DD74_05185 GN {ECO:0000313|EMBL:KTY17195.1}, DD81_09720 GN {ECO:0000313|EMBL:KTY52294.1}, DD84_17705 GN {ECO:0000313|EMBL:KTY63168.1}, DD95_06320 GN {ECO:0000313|EMBL:KTZ14029.1}, DD96_06840 GN {ECO:0000313|EMBL:KTZ19388.1}, DE49_09440 GN {ECO:0000313|EMBL:KUB61712.1}, DE50_12480 GN {ECO:0000313|EMBL:KUB63203.1}, DE51_00915 GN {ECO:0000313|EMBL:KUB84215.1}, DE52_04695 GN {ECO:0000313|EMBL:KUB78586.1}, DE53_15570 GN {ECO:0000313|EMBL:KUB76189.1}, DE91_09350 GN {ECO:0000313|EMBL:KUD68669.1}, DE95_14360 GN {ECO:0000313|EMBL:KUD82236.1}, ERS450001_03709 GN {ECO:0000313|EMBL:CKH84803.1}, SE15cs_03645 GN {ECO:0000313|EMBL:ALE63992.1}; OS Salmonella typhimurium. OG Plasmid 2 {ECO:0000313|EMBL:CKH84803.1}. OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales; OC Enterobacteriaceae; Salmonella. OX NCBI_TaxID=90371 {ECO:0000313|EMBL:CKH84803.1}; RN [1] {ECO:0000313|EMBL:KTW47802.1} RP NUCLEOTIDE SEQUENCE. RC STRAIN=CVM N29313 {ECO:0000313|EMBL:KTW47802.1}, CVM N29323 RC {ECO:0000313|EMBL:KTW68212.1}, CVM N29338 RC {ECO:0000313|EMBL:KTW71700.1}, CVM N30696 RC {ECO:0000313|EMBL:KTY17195.1}, CVM N31395 RC {ECO:0000313|EMBL:KTY52294.1}, CVM N31409 RC {ECO:0000313|EMBL:KTY63168.1}, CVM N32045 RC {ECO:0000313|EMBL:KTZ14029.1}, CVM N32048 RC {ECO:0000313|EMBL:KTZ19388.1}, CVM N38914 RC {ECO:0000313|EMBL:KUB61712.1}, CVM N38917 RC {ECO:0000313|EMBL:KUB63203.1}, CVM N38921 RC {ECO:0000313|EMBL:KUB84215.1}, CVM N38925 RC {ECO:0000313|EMBL:KUB78586.1}, CVM N38929 RC {ECO:0000313|EMBL:KUB76189.1}, CVM N42450 RC {ECO:0000313|EMBL:KUD68669.1}, and CVM N42467 RC {ECO:0000313|EMBL:KUD82236.1}; RA Chen Y., Folster J., Ayers S., Kabera C., Li C., Mukherjee S., Lam C., RA Zhao S., McDermott P.; RT "Salmonella Genotype and Phenotype Association."; RL Submitted (SEP-2014) to the EMBL/GenBank/DDBJ databases. RN [2] {ECO:0000313|EMBL:CKH84803.1} RP NUCLEOTIDE SEQUENCE. RC STRAIN=NCTC13348 {ECO:0000313|EMBL:CKH84803.1}; RC PLASMID=2 {ECO:0000313|EMBL:CKH84803.1}; RA Informatics Pathogen; RL Submitted (MAR-2015) to the EMBL/GenBank/DDBJ databases. RN [3] {ECO:0000313|EMBL:KMM48493.1} RP NUCLEOTIDE SEQUENCE. RC STRAIN=Smonpas0023280 {ECO:0000313|EMBL:KMM48493.1}; RA Orsini M.; RT "Draft genome sequences of nineteen Salmonella enterica serovar RT typhimurium [4,5:i:-] resistant to nalidixic acid from a long term RT outbreak in Italy."; RL Submitted (MAY-2015) to the EMBL/GenBank/DDBJ databases. RN [4] {ECO:0000313|EMBL:KLT23827.1} RP NUCLEOTIDE SEQUENCE. RC STRAIN=Smonpas001102-2 {ECO:0000313|EMBL:KLT35658.1}, Smonpas008251-3 RC {ECO:0000313|EMBL:KLT25918.1}, Smonpas008251-5 RC {ECO:0000313|EMBL:KLT24717.1}, and Smonpas009865-1 RC {ECO:0000313|EMBL:KLT23827.1}; RA Orsini M., Mangone I., DiPasquale A., Perticara S., Marcacci M., RA Ancora M., Sacchini L., Migliorati G., DiGiannatale E., Camma' C.; RT "Draft genome sequences of nineteen Salmonella enterica serovar RT Typhimurium [4,5,:i:-] resistant to nalidixic acid from a long term RT outbreak in Italy."; RL Submitted (JUN-2015) to the EMBL/GenBank/DDBJ databases. RN [5] {ECO:0000313|EMBL:KMJ17912.1} RP NUCLEOTIDE SEQUENCE. RC STRAIN=Smonpas001102-11 {ECO:0000313|EMBL:KMJ77482.1}, RC Smonpas001102-13 {ECO:0000313|EMBL:KMJ17912.1}, Smonpas003168-4 RC {ECO:0000313|EMBL:KMJ25351.1}, Smonpas003168-5 RC {ECO:0000313|EMBL:KMJ36185.1}, Smonpas004260-1 RC {ECO:0000313|EMBL:KMJ19010.1}, Smonpas004260-10 RC {ECO:0000313|EMBL:KMJ34320.1}, Smonpas004260-8 RC {ECO:0000313|EMBL:KMJ33273.1}, Smonpas006644-5 RC {ECO:0000313|EMBL:KMJ61402.1}, and Smonpas007416-4 RC {ECO:0000313|EMBL:KMJ74619.1}; RA Orsini M., Mangone I., DiPasquale A., Perticara S., Marcacci M., RA Ancora M., Sacchini L., Migliorati G., DiGiannatale E., Camma' C.; RT "Draft Genome Sequences of nineteen Salmonella enterica serovar RT typhimurium [4,5,:i:-] resistant to Nalidixic Acid from a long term RT outbreak in Italy."; RL Submitted (JUN-2015) to the EMBL/GenBank/DDBJ databases. RN [6] {ECO:0000313|EMBL:KLT11990.1} RP NUCLEOTIDE SEQUENCE. RC STRAIN=Smonpas0031082 {ECO:0000313|EMBL:KLT11990.1}; RA Orsini M.; RT "Draft genome sequences of nineteen Salmonella enterica serovar RT Typhimurium [4,5,:i:-] resistant to nalidixic acid from a long term RT outbreak in Italy."; RL Submitted (JUN-2015) to the EMBL/GenBank/DDBJ databases. RN [7] {ECO:0000313|EMBL:KTA23522.1} RP NUCLEOTIDE SEQUENCE. RC STRAIN=2013LSAL04524 {ECO:0000313|EMBL:KTA23522.1}; RA Webb H.E., Granier S.A., Nightingale K., Den Bakker H.C., Marault M., RA Bugarel M., Loneragan G.H.; RT "Characterization of colistin resistance mechanisms in Salmonella of RT French origin."; RL Submitted (SEP-2015) to the EMBL/GenBank/DDBJ databases. RN [8] {ECO:0000313|EMBL:ALE63992.1} RP NUCLEOTIDE SEQUENCE. RC STRAIN=33676 {ECO:0000313|EMBL:ALE63992.1}; RA Vinuesa P., Silva C., Calva E.; RT "Complete genome sequencing of a multidrug-resistant and human- RT invasive Salmonella Typhimurium strain of the emerging sequence type RT 213 harboring a blaCMY-2-carrying IncF plasmid."; RL Submitted (SEP-2015) to the EMBL/GenBank/DDBJ databases. CC -!- FUNCTION: Phosphorylase is an important allosteric enzyme in CC carbohydrate metabolism. Enzymes from different sources differ in CC their regulatory mechanisms and in their natural substrates. CC However, all known phosphorylases share catalytic and structural CC properties. {ECO:0000256|RuleBase:RU000587}. CC -!- CATALYTIC ACTIVITY: ((1->4)-alpha-D-glucosyl)(n) + phosphate = CC ((1->4)-alpha-D-glucosyl)(n-1) + alpha-D-glucose 1-phosphate. CC {ECO:0000256|RuleBase:RU000587}. CC -!- COFACTOR: CC Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326; CC Evidence={ECO:0000256|RuleBase:RU000587}; CC -!- SIMILARITY: Belongs to the glycogen phosphorylase family. CC {ECO:0000256|RuleBase:RU004179}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; CP012681; ALE63992.1; -; Genomic_DNA. DR EMBL; LN829402; CKH84803.1; -; Genomic_DNA. DR EMBL; LDYH01000006; KLT11990.1; -; Genomic_DNA. DR EMBL; LECC01000011; KLT23827.1; -; Genomic_DNA. DR EMBL; LECB01000012; KLT24717.1; -; Genomic_DNA. DR EMBL; LECA01000009; KLT25918.1; -; Genomic_DNA. DR EMBL; LECD01000013; KLT35658.1; -; Genomic_DNA. DR EMBL; LFCG01000009; KMJ17912.1; -; Genomic_DNA. DR EMBL; LFCI01000011; KMJ19010.1; -; Genomic_DNA. DR EMBL; LFCH01000021; KMJ25351.1; -; Genomic_DNA. DR EMBL; LFDY01000023; KMJ33273.1; -; Genomic_DNA. DR EMBL; LFDX01000010; KMJ34320.1; -; Genomic_DNA. DR EMBL; LFDZ01000013; KMJ36185.1; -; Genomic_DNA. DR EMBL; LFGM01000013; KMJ61402.1; -; Genomic_DNA. DR EMBL; LFGO01000010; KMJ74619.1; -; Genomic_DNA. DR EMBL; LFGQ01000014; KMJ77482.1; -; Genomic_DNA. DR EMBL; LDPA01000008; KMM48493.1; -; Genomic_DNA. DR EMBL; LKJD01000013; KTA23522.1; -; Genomic_DNA. DR EMBL; JYTP01000048; KTW47802.1; -; Genomic_DNA. DR EMBL; JYTT01000007; KTW68212.1; -; Genomic_DNA. DR EMBL; JYTU01000020; KTW71700.1; -; Genomic_DNA. DR EMBL; JYUZ01000007; KTY17195.1; -; Genomic_DNA. DR EMBL; JYVG01000017; KTY52294.1; -; Genomic_DNA. DR EMBL; JYVJ01000042; KTY63168.1; -; Genomic_DNA. DR EMBL; JYVU01000013; KTZ14029.1; -; Genomic_DNA. DR EMBL; JYVV01000014; KTZ19388.1; -; Genomic_DNA. DR EMBL; JYXW01000014; KUB61712.1; -; Genomic_DNA. DR EMBL; JYXX01000016; KUB63203.1; -; Genomic_DNA. DR EMBL; JYYA01000026; KUB76189.1; -; Genomic_DNA. DR EMBL; JYXZ01000005; KUB78586.1; -; Genomic_DNA. DR EMBL; JYXY01000002; KUB84215.1; -; Genomic_DNA. DR EMBL; JYZN01000016; KUD68669.1; -; Genomic_DNA. DR EMBL; JYZR01000020; KUD82236.1; -; Genomic_DNA. DR RefSeq; WP_000993428.1; NZ_LIOJ01000035.1. DR KEGG; seni:CY43_18360; -. DR KO; K00688; -. DR GO; GO:0008184; F:glycogen phosphorylase activity; IEA:InterPro. DR GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro. DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:UniProtKB-KW. DR InterPro; IPR011833; Glycg_phsphrylas. DR InterPro; IPR000811; Glyco_trans_35. DR PANTHER; PTHR11468; PTHR11468; 1. DR Pfam; PF00343; Phosphorylase; 1. DR PIRSF; PIRSF000460; Pprylas_GlgP; 1. DR TIGRFAMs; TIGR02093; P_ylase; 1. DR PROSITE; PS00102; PHOSPHORYLASE; 1. PE 3: Inferred from homology; KW Carbohydrate metabolism {ECO:0000256|RuleBase:RU000587}; KW Glycosyltransferase {ECO:0000256|RuleBase:RU000587, KW ECO:0000313|EMBL:CKH84803.1}; Plasmid {ECO:0000313|EMBL:CKH84803.1}; KW Pyridoxal phosphate {ECO:0000256|PIRSR:PIRSR000460-1, KW ECO:0000256|RuleBase:RU000587}; KW Transferase {ECO:0000256|RuleBase:RU000587, KW ECO:0000313|EMBL:CKH84803.1}. FT MOD_RES 662 662 N6-(pyridoxal phosphate)lysine. FT {ECO:0000256|PIRSR:PIRSR000460-1}. SQ SEQUENCE 815 AA; 93343 MW; 4464A9CBB044F1C2 CRC64; MNAPFTYASP TLSVEALKHS IAYKLMFTIG KDPVIANKHE WLNATLFAVR DRLVERWLRS NRAQLSQETR QVYYLSMEFL IGRTLSNALL SLGIYDDVKG ALEAMGLDLE ELIDEENDPG LGNGGLGRLA ACFLDSLATL GLPGRGYGIR YDYGMFKQNI VDGRQKESPD YWLEYGNPWE FKRHNTRYKV LFGGRIQQEG KKARWIETEE ILAVAYDQII PGYDTDATNT LRLWNAQASS EINLGKFNQG DYFAAVEDKN HSENVSRVLY PDDSTYSGRE LRLRQEYFLV SATVQDILHR HYQLHKTYEN LADKIAIHLN DTHPVLSIPE LMRLLIDEHK FSWDDAFEVC CQVFSYTNHT LMSEALETWP VDMLGKILPR HLQIIFEIND YFLKTVQEQY PNDTSLLGRA SIIDESNGRR VRMAWLAVVV SHKVNGVSEL HSNLMVQSLF ADFAKIFPTR FCNVTNGVTP RRWLALANPP LSDVLDENIG RTWRTDLSQL SELKQHCDYP LVNHAVRQAK LENKKRLAVV IAQQLNVVVN PKALFDVQIK RIHEYKRQLM NVLHVITRYN RIKENPEADW VPRVNIFAGK AASAYYMAKH IIHLINDVAK VINNDPQIGD KLKVVFIPNY SVSLAQVIIP AADLSEQISL AGTEASGTSN MKFALNGALT IGTLDGANVE MQEHIGEENI FIFGNTAEEV EALRRQGYKP RDYYEKDEEL HQVLTQIGSG VFNPEEPGRY RDLVDSLINF GDHYQVLADY RSYVDCQDKV DELYRRPEEW TTKAMLNIAN MGYFSSDRTI KEYAENIWHI DPVRL //