ID A0A0D2XQG4_FUSO4 Unreviewed; 487 AA. AC A0A0D2XQG4; DT 29-APR-2015, integrated into UniProtKB/TrEMBL. DT 29-APR-2015, sequence version 1. DT 31-JUL-2019, entry version 23. DE SubName: Full=NAD-dependent histone deacetylase SIR2 {ECO:0000313|EMBL:KNB03874.1}; GN ORFNames=FOXG_06210 {ECO:0000313|EMBL:KNB03874.1}; OS Fusarium oxysporum f. sp. lycopersici (strain 4287 / CBS 123668 / FGSC OS 9935 / NRRL 34936) (Fusarium vascular wilt of tomato). OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; OC Sordariomycetes; Hypocreomycetidae; Hypocreales; Nectriaceae; OC Fusarium; Fusarium oxysporum species complex. OX NCBI_TaxID=426428 {ECO:0000313|EnsemblFungi:FOXG_06210P0, ECO:0000313|Proteomes:UP000009097}; RN [1] {ECO:0000313|EMBL:KNB03874.1} RP NUCLEOTIDE SEQUENCE. RC STRAIN=4287 {ECO:0000313|EMBL:KNB03874.1}; RG The Broad Institute Genome Sequencing Platform; RA Birren B., Lander E., Galagan J., Nusbaum C., Devon K., Ma L.-J., RA Jaffe D., Butler J., Alvarez P., Gnerre S., Grabherr M., Kleber M., RA Mauceli E., Brockman W., MacCallum I.A., Young S., LaButti K., RA DeCaprio D., Crawford M., Koehrsen M., Engels R., Montgomery P., RA Pearson M., Howarth C., Larson L., White J., O'Leary S., Kodira C., RA Zeng Q., Yandava C., Alvarado L., Kistler C., Shim W.-B., Kang S., RA Woloshuk C.; RL Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases. RN [2] {ECO:0000313|EMBL:KNB03874.1, ECO:0000313|EnsemblFungi:FOXG_06210P0, ECO:0000313|Proteomes:UP000009097} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=4287 {ECO:0000313|EMBL:KNB03874.1}, and 4287 / CBS 123668 / RC FGSC 9935 / NRRL 34936 {ECO:0000313|EnsemblFungi:FOXG_06210P0, RC ECO:0000313|Proteomes:UP000009097}; RX PubMed=20237561; DOI=10.1038/nature08850; RA Ma L.-J., van der Does H.C., Borkovich K.A., Coleman J.J., RA Daboussi M.-J., Di Pietro A., Dufresne M., Freitag M., Grabherr M., RA Henrissat B., Houterman P.M., Kang S., Shim W.-B., Woloshuk C., RA Xie X., Xu J.-R., Antoniw J., Baker S.E., Bluhm B.H., Breakspear A., RA Brown D.W., Butchko R.A.E., Chapman S., Coulson R., Coutinho P.M., RA Danchin E.G.J., Diener A., Gale L.R., Gardiner D.M., Goff S., RA Hammond-Kosack K.E., Hilburn K., Hua-Van A., Jonkers W., Kazan K., RA Kodira C.D., Koehrsen M., Kumar L., Lee Y.-H., Li L., Manners J.M., RA Miranda-Saavedra D., Mukherjee M., Park G., Park J., Park S.-Y., RA Proctor R.H., Regev A., Ruiz-Roldan M.C., Sain D., Sakthikumar S., RA Sykes S., Schwartz D.C., Turgeon B.G., Wapinski I., Yoder O., RA Young S., Zeng Q., Zhou S., Galagan J., Cuomo C.A., Kistler H.C., RA Rep M.; RT "Comparative genomics reveals mobile pathogenicity chromosomes in RT Fusarium."; RL Nature 464:367-373(2010). RN [3] {ECO:0000313|EnsemblFungi:FOXG_06210P0} RP IDENTIFICATION. RC STRAIN=4287 / CBS 123668 / FGSC 9935 / NRRL 34936 RC {ECO:0000313|EnsemblFungi:FOXG_06210P0}; RG EnsemblFungi; RL Submitted (MAR-2015) to UniProtKB. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; DS231701; KNB03874.1; -; Genomic_DNA. DR RefSeq; XP_018241919.1; XM_018384765.1. DR EnsemblFungi; FOXG_06210T0; FOXG_06210P0; FOXG_06210. DR GeneID; 28948117; -. DR KEGG; fox:FOXG_06210; -. DR KO; K11121; -. DR OMA; CHGSWAT; -. DR Proteomes; UP000009097; Chromosome 2. DR GO; GO:0070403; F:NAD+ binding; IEA:InterPro. DR Gene3D; 3.30.1600.10; -; 1. DR InterPro; IPR029035; DHS-like_NAD/FAD-binding_dom. DR InterPro; IPR003000; Sirtuin. DR InterPro; IPR026591; Sirtuin_cat_small_dom_sf. DR InterPro; IPR026590; Ssirtuin_cat_dom. DR Pfam; PF02146; SIR2; 1. DR SUPFAM; SSF52467; SSF52467; 1. DR PROSITE; PS50305; SIRTUIN; 1. PE 4: Predicted; KW Coiled coil {ECO:0000256|SAM:Coils}; KW Complete proteome {ECO:0000313|Proteomes:UP000009097}; KW Reference proteome {ECO:0000313|Proteomes:UP000009097}. FT DOMAIN 165 456 Deacetylase sirtuin-type. FT {ECO:0000259|PROSITE:PS50305}. FT REGION 1 33 Disordered. {ECO:0000256|SAM:MobiDB- FT lite}. FT REGION 328 358 Disordered. {ECO:0000256|SAM:MobiDB- FT lite}. FT COILED 37 57 {ECO:0000256|SAM:Coils}. SQ SEQUENCE 487 AA; 54592 MW; F20FF1B4F1F44E70 CRC64; MHTKKGNGRT VALSKRKAQP NALDKLGDNP TEDEIKTAEA NVALAELEER VADVRESWET DSLFEDAFDE LNADNTVAIN DPKVCTPEEA SRLRRELREY GPTVFCQRTV DAGHYTARKL LSAFGIRPPP FLEGQPDDAY FSLLSLAITR ELSKRAKLLR HNTVDDAVDL ITKSNNIILI TGAGISTSLG IPDFRSKGTG LYSKLEHLGL SDPQEVFDIG VFRQDPTIFY SVAKDILPST DRYTPTHKFI AMLHEKGKLL TNYSQNIDNL EVKAGVPKDK LIQCHGSFGT ATCVQCGYKC PGEAIFPEIK ADKIPRCPRC IQTLRTTGGA PKRKRSAGTE KKRRRWSADS SDESEYDIPS AGVMKPDITF FGEALPDEFS RRLTEHDRDK VDLVIVIGTS LKVTPVSEIV SWLPAHIPQI YVSRQAVNHI NFDIDLLGDC DVVVSELCRR LRWPMVHDMV PKNQKVEVRT EPGYKSRHVF EEQKTKK //