ID A0A0D2BBY4_9EURO Unreviewed; 353 AA. AC A0A0D2BBY4; DT 29-APR-2015, integrated into UniProtKB/TrEMBL. DT 29-APR-2015, sequence version 1. DT 02-DEC-2020, entry version 23. DE RecName: Full=Fructose-bisphosphatase {ECO:0000256|ARBA:ARBA00013093}; DE EC=3.1.3.11 {ECO:0000256|ARBA:ARBA00013093}; GN ORFNames=PV05_11307 {ECO:0000313|EMBL:KIW49646.1}; OS Exophiala xenobiotica. OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes; OC Chaetothyriomycetidae; Chaetothyriales; Herpotrichiellaceae; Exophiala. OX NCBI_TaxID=348802 {ECO:0000313|EMBL:KIW49646.1, ECO:0000313|Proteomes:UP000054342}; RN [1] {ECO:0000313|EMBL:KIW49646.1, ECO:0000313|Proteomes:UP000054342} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=CBS 118157 {ECO:0000313|EMBL:KIW49646.1, RC ECO:0000313|Proteomes:UP000054342}; RG The Broad Institute Genomics Platform; RA Cuomo C., de Hoog S., Gorbushina A., Stielow B., Teixiera M., RA Abouelleil A., Chapman S.B., Priest M., Young S.K., Wortman J., Nusbaum C., RA Birren B.; RT "The Genome Sequence of Exophiala xenobiotica CBS118157."; RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases. CC -!- CATALYTIC ACTIVITY: CC Reaction=beta-D-fructose 1,6-bisphosphate + H2O = beta-D-fructose 6- CC phosphate + phosphate; Xref=Rhea:RHEA:11064, ChEBI:CHEBI:15377, CC ChEBI:CHEBI:32966, ChEBI:CHEBI:43474, ChEBI:CHEBI:57634; EC=3.1.3.11; CC Evidence={ECO:0000256|ARBA:ARBA00001273}; CC -!- COFACTOR: CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420; CC Evidence={ECO:0000256|ARBA:ARBA00001946}; CC -!- SIMILARITY: Belongs to the FBPase class 1 family. CC {ECO:0000256|ARBA:ARBA00010941, ECO:0000256|RuleBase:RU000508}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; KN847323; KIW49646.1; -; Genomic_DNA. DR RefSeq; XP_013310230.1; XM_013454776.1. DR EnsemblFungi; KIW49646; KIW49646; PV05_11307. DR GeneID; 25333215; -. DR HOGENOM; CLU_039977_1_0_1; -. DR OrthoDB; 1381522at2759; -. DR Proteomes; UP000054342; Unassembled WGS sequence. DR GO; GO:0042132; F:fructose 1,6-bisphosphate 1-phosphatase activity; IEA:UniProtKB-EC. DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:UniProtKB-KW. DR CDD; cd00354; FBPase; 1. DR HAMAP; MF_01855; FBPase_class1; 1. DR InterPro; IPR044015; FBPase_C_dom. DR InterPro; IPR000146; FBPase_class-1. DR InterPro; IPR033391; FBPase_N. DR InterPro; IPR028343; FBPtase. DR InterPro; IPR020548; Fructose_bisphosphatase_AS. DR PANTHER; PTHR11556; PTHR11556; 1. DR Pfam; PF00316; FBPase; 1. DR Pfam; PF18913; FBPase_C; 1. DR PIRSF; PIRSF500210; FBPtase; 1. DR PIRSF; PIRSF000904; FBPtase_SBPase; 1. DR PRINTS; PR00115; F16BPHPHTASE. DR PROSITE; PS00124; FBPASE; 1. PE 3: Inferred from homology; KW Carbohydrate metabolism {ECO:0000256|ARBA:ARBA00023277, KW ECO:0000256|RuleBase:RU000508}; KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU000508}; KW Magnesium {ECO:0000256|ARBA:ARBA00022842}; KW Metal-binding {ECO:0000256|ARBA:ARBA00022723}; KW Reference proteome {ECO:0000313|Proteomes:UP000054342}. FT DOMAIN 26..217 FT /note="FBPase" FT /evidence="ECO:0000259|Pfam:PF00316" FT DOMAIN 221..352 FT /note="FBPase_C" FT /evidence="ECO:0000259|Pfam:PF18913" SQ SEQUENCE 353 AA; 38378 MW; B6924941AA9383DF CRC64; MAANGNGESN GYTTGTGQEK INTEIITLTR FLTEEQTKHK EATGDFTLLC HALQFSFKSI AYYIRRATLI NLTGLAGSSN TTGDDQKKLD VIGNDLFIAA MRGSGRCRAL VSEEEEEIIY FDESPGARYV VACDPIDGSS NLDAGVSVGT IFGIMKLPEG VAGKPKPEDL LMPGTELIAA GFTMYGASAQ LVITMKGGTV NGFTLDNALG EFILTHPNMR IPKKRAIYSV NEGNSLYWDD KTKGYFESLK YPAKEGGKPY SARYIGSMVA DAYRTLLYGG IFAYPADKKS PKGKLRILYE CAPMAMVMEN AGGKAVDSKM ERMLAVKPTN IHDRSGIFMG SPEEMDKVLE AHK //