ID A0A0D0V8J3_9TREE Unreviewed; 943 AA. AC A0A0D0V8J3; DT 29-APR-2015, integrated into UniProtKB/TrEMBL. DT 29-APR-2015, sequence version 1. DT 18-JAN-2017, entry version 12. DE RecName: Full=Phospholipid-transporting ATPase {ECO:0000256|RuleBase:RU362033}; DE EC=3.6.3.1 {ECO:0000256|RuleBase:RU362033}; GN ORFNames=I313_03119 {ECO:0000313|EMBL:KIR41165.1}; OS Cryptococcus gattii VGII Ram5. OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; OC Tremellomycetes; Tremellales; Cryptococcaceae; Cryptococcus; OC Cryptococcus gattii species complex. OX NCBI_TaxID=1296110 {ECO:0000313|EMBL:KIR41165.1, ECO:0000313|Proteomes:UP000053392}; RN [1] {ECO:0000313|EMBL:KIR41165.1, ECO:0000313|Proteomes:UP000053392} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Ram5 {ECO:0000313|EMBL:KIR41165.1, RC ECO:0000313|Proteomes:UP000053392}; RG The Broad Institute Genomics Platform; RA Cuomo C., Litvintseva A., Chen Y., Heitman J., Sun S., Springer D., RA Dromer F., Young S., Zeng Q., Gargeya S., Abouelleil A., Alvarado L., RA Chapman S.B., Gainer-Dewar J., Goldberg J., Griggs A., Gujja S., RA Hansen M., Howarth C., Imamovic A., Larimer J., Murphy C., Naylor J., RA Pearson M., Priest M., Roberts A., Saif S., Shea T., Sykes S., RA Wortman J., Nusbaum C., Birren B.; RT "The Genome Sequence of Cryptococcus gattii Ram5."; RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases. CC -!- CATALYTIC ACTIVITY: ATP + H(2)O + phospholipid(Side 1) = ADP + CC phosphate + phospholipid(Side 2). {ECO:0000256|RuleBase:RU362033, CC ECO:0000256|SAAS:SAAS00036652}. CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|RuleBase:RU362033}; CC Multi-pass membrane protein {ECO:0000256|RuleBase:RU362033}. CC -!- SIMILARITY: Belongs to the cation transport ATPase (P-type) (TC CC 3.A.3) family. Type IV subfamily. {ECO:0000256|RuleBase:RU362033, CC ECO:0000256|SAAS:SAAS00534025}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; KN847901; KIR41165.1; -; Genomic_DNA. DR EnsemblFungi; KIR41165; KIR41165; I313_03119. DR Proteomes; UP000053392; Unassembled WGS sequence. DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW. DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW. DR GO; GO:0000287; F:magnesium ion binding; IEA:InterPro. DR GO; GO:0004012; F:phospholipid-translocating ATPase activity; IEA:UniProtKB-EC. DR Gene3D; 2.70.150.10; -; 2. DR Gene3D; 3.40.1110.10; -; 1. DR Gene3D; 3.40.50.1000; -; 2. DR InterPro; IPR023299; ATPase_P-typ_cyto_domN. DR InterPro; IPR018303; ATPase_P-typ_P_site. DR InterPro; IPR008250; ATPase_P-typ_transduc_dom_A. DR InterPro; IPR023214; HAD-like_dom. DR InterPro; IPR006539; P-type_ATPase_IV. DR InterPro; IPR001757; P_typ_ATPase. DR InterPro; IPR032630; P_typ_ATPase_c. DR PANTHER; PTHR24092; PTHR24092; 2. DR Pfam; PF00122; E1-E2_ATPase; 1. DR Pfam; PF16212; PhoLip_ATPase_C; 1. DR SUPFAM; SSF56784; SSF56784; 1. DR SUPFAM; SSF81660; SSF81660; 2. DR TIGRFAMs; TIGR01652; ATPase-Plipid; 1. DR TIGRFAMs; TIGR01494; ATPase_P-type; 2. DR PROSITE; PS00154; ATPASE_E1_E2; 1. PE 3: Inferred from homology; KW ATP-binding {ECO:0000256|RuleBase:RU362033, KW ECO:0000256|SAAS:SAAS00076996}; KW Complete proteome {ECO:0000313|Proteomes:UP000053392}; KW Hydrolase {ECO:0000256|RuleBase:RU362033, KW ECO:0000256|SAAS:SAAS00076955}; KW Magnesium {ECO:0000256|SAAS:SAAS00076983}; KW Membrane {ECO:0000256|RuleBase:RU362033, KW ECO:0000256|SAAS:SAAS00414847}; KW Nucleotide-binding {ECO:0000256|RuleBase:RU362033, KW ECO:0000256|SAAS:SAAS00076966}; KW Transmembrane {ECO:0000256|RuleBase:RU362033, KW ECO:0000256|SAAS:SAAS00076989}; KW Transmembrane helix {ECO:0000256|RuleBase:RU362033, KW ECO:0000256|SAAS:SAAS00076942}. FT TRANSMEM 209 228 Helical. {ECO:0000256|RuleBase:RU362033}. FT TRANSMEM 234 253 Helical. {ECO:0000256|RuleBase:RU362033}. FT TRANSMEM 741 764 Helical. {ECO:0000256|RuleBase:RU362033}. FT TRANSMEM 770 789 Helical. {ECO:0000256|RuleBase:RU362033}. FT TRANSMEM 819 839 Helical. {ECO:0000256|RuleBase:RU362033}. FT TRANSMEM 845 866 Helical. {ECO:0000256|RuleBase:RU362033}. FT TRANSMEM 873 895 Helical. {ECO:0000256|RuleBase:RU362033}. FT TRANSMEM 907 925 Helical. {ECO:0000256|RuleBase:RU362033}. FT DOMAIN 51 255 E1-E2_ATPase. {ECO:0000259|Pfam:PF00122}. FT DOMAIN 707 934 PhoLip_ATPase_C. {ECO:0000259|Pfam: FT PF16212}. SQ SEQUENCE 943 AA; 104329 MW; D8C98443BCD81FC8 CRC64; MGKEAFDDYS RYLRDREANS TRYLVLVPQP PSPNPSSDRE QTPSLPRPQT RSTPASSIKV GDMVLLEKNQ RVPADMVLLT TSEEEGTCFI RTDQLDGETD WKLKVAVGET HKMGEAFVGN AEGSLYADPP IKDIHTFYGV FTLRSTSPGE QTETSTPLSV ENVLWANTVL AAGSAVGLVV YTGKETRAVL NTSEAGTKMG TLEKEVNKMA KILCTVTFAL SVFLVALNGF RGHWYIYVFR FLILFSSIIP ISLRVNLDMG KTVYAHQIQV DREIPETIVR TSTLPEELGR VEYLLSDKTG TLTRNEMELK KLHMGTLVFG WDSMDEVSHL LSQALDETSG PHGRQGSLPG GNQRGKRDMT GRVRDTVMAL ATCHNVTPVI NDDGTTTYQA SSPDEVAIVQ WTESVGLTLT SRDRTSMVVR TSAGRSLTFD ILSVFPFTSE SKRMGIIIKD RETGGVTFVQ KGADVVMSKI VHKNDWLEEE TGNMAREGLR TLVLGRKKLS EETYAAFDKA YRAAQLLPSE SRASSIASVI SQHLENELEL LALTGVEDKL QEDVKSTLEL LRNAGLKIWM LTGDKIETAT NIAVSSKLVA RGQYIHQVAK LRTADQVRDM LDFLHTKLDC ALVIDGESLQ LALDRFRSEF IILATQLPIV VACRCSPTQK ADVAKLIREF TKKTVCCIGD GGNDVSMIQA ADVGVGIVGK EGKQASLAAD FSINQFSYLT KLLLWHGRNS YKRSAKLSQF VIHRGLIIAV IQAVFSSIFF FAPIALYQGW LQVGYATLYT MAPVFSLVLD KDVNEDLALL YPELYKDLTK GRSLSYKTFF TWLTISVYQG GIIMLLSLLL FESEFLHIVA ISFTSLVINE LIMVALEVTT WHSYMVLSEL GTALVYFGSM AVLPAYFDLT FVLSSTFVYK VAVIVAVSSF PLYVIKAAHQ RLNPAAYKKV AGI //