ID A0A0C9QKP6_BIOGL Unreviewed; 300 AA. AC A0A0C9QKP6; DT 29-APR-2015, integrated into UniProtKB/TrEMBL. DT 29-APR-2015, sequence version 1. DT 14-OCT-2015, entry version 4. DE RecName: Full=Palmitoyltransferase {ECO:0000256|RuleBase:RU079119}; DE EC=2.3.1.225 {ECO:0000256|RuleBase:RU079119}; GN Name=plmt {ECO:0000313|EMBL:JAG85125.1}; OS Biomphalaria glabrata (Bloodfluke planorb) (Freshwater snail). OC Eukaryota; Metazoa; Lophotrochozoa; Mollusca; Gastropoda; OC Heterobranchia; Euthyneura; Panpulmonata; Hygrophila; Planorboidea; OC Planorbidae; Biomphalaria. OX NCBI_TaxID=6526 {ECO:0000313|EMBL:JAG85125.1}; RN [1] {ECO:0000313|EMBL:JAG85125.1} RP NUCLEOTIDE SEQUENCE. RC STRAIN=Guadeloupe {ECO:0000313|EMBL:JAG85125.1}; RC TISSUE=Whole body {ECO:0000313|EMBL:JAG85125.1}; RA Tennessen J.A., Blouin M.S.; RL Submitted (DEC-2014) to the EMBL/GenBank/DDBJ databases. RN [2] {ECO:0000313|EMBL:JAG85125.1} RP NUCLEOTIDE SEQUENCE. RC STRAIN=Guadeloupe {ECO:0000313|EMBL:JAG85125.1}; RC TISSUE=Whole body {ECO:0000313|EMBL:JAG85125.1}; RA Theron A., Marine M., Yeh J.-Y., Rognon A.; RT "Hyperdiverse gene cluster in snail host conveys resistance to human RT schistosome parasites."; RL Submitted (FEB-2015) to the EMBL/GenBank/DDBJ databases. CC -!- CATALYTIC ACTIVITY: Palmitoyl-CoA + [protein]-L-cysteine = CC [protein]-S-palmitoyl-L-cysteine + CoA. CC {ECO:0000256|RuleBase:RU079119}. CC -!- DOMAIN: The DHHC domain is required for palmitoyltransferase CC activity. {ECO:0000256|RuleBase:RU079119}. CC -!- SIMILARITY: Belongs to the DHHC palmitoyltransferase family. CC {ECO:0000256|RuleBase:RU079119}. CC -!- SIMILARITY: Contains 0 DHHC-type zinc fingers. CC {ECO:0000256|RuleBase:RU079119}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; GBYU01000014; JAG85125.1; -; Transcribed_RNA. DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW. DR GO; GO:0019706; F:protein-cysteine S-palmitoyltransferase activity; IEA:UniProtKB-EC. DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro. DR InterPro; IPR001594; Znf_DHHC_palmitoyltrfase. DR Pfam; PF01529; zf-DHHC; 1. DR PROSITE; PS50216; ZF_DHHC; 1. PE 3: Inferred from homology; KW Acyltransferase {ECO:0000256|RuleBase:RU079119}; KW Membrane {ECO:0000256|RuleBase:RU079119}; KW Metal-binding {ECO:0000256|RuleBase:RU079119, KW ECO:0000256|SAAS:SAAS00117307}; KW Transferase {ECO:0000256|RuleBase:RU079119}; KW Transmembrane {ECO:0000256|RuleBase:RU079119}; KW Transmembrane helix {ECO:0000256|RuleBase:RU079119}; KW Zinc {ECO:0000256|RuleBase:RU079119, ECO:0000256|SAAS:SAAS00117282}; KW Zinc-finger {ECO:0000256|RuleBase:RU079119, KW ECO:0000256|SAAS:SAAS00117305}. FT TRANSMEM 12 33 Helical. {ECO:0000256|RuleBase:RU079119}. FT TRANSMEM 39 57 Helical. {ECO:0000256|RuleBase:RU079119}. FT TRANSMEM 160 184 Helical. {ECO:0000256|RuleBase:RU079119}. FT TRANSMEM 204 226 Helical. {ECO:0000256|RuleBase:RU079119}. SQ SEQUENCE 300 AA; 34469 MW; 714A33C504B02CEA CRC64; MSIWGWVPPL VISMVAVYTY YAYVVAMCIM TSNLLAEKVI LILVFHALFA MSVWCFVRSV WTRPMKPTVK YALEEAEWSK MSYDYNWKKE REAMSNLRQK VGIITTASDT GDGLLQYCFH CRNLKPDRCH HCSRCGMCVL KMDHHCPWVN NCVGFHNYKY FLLFLSYSSF GVIFVIFTSA RFIYEFVINA RHLGLASAVS GNVLVILIML VIHVLVGIAL SPLLYLHRDL VAHNVTTLEN SRPVGVYGTR PSYKTFDMGL QANFVQIFGE RKLYWFFPVF TSQGDGMTFP ISTYKKTEIA //