ID A0A0B7MHT7_MOUSE Unreviewed; 63 AA. AC A0A0B7MHT7; DT 01-APR-2015, integrated into UniProtKB/TrEMBL. DT 01-APR-2015, sequence version 1. DT 16-SEP-2015, entry version 4. DE SubName: Full=Tet methylcytosine dioxygenase 1 {ECO:0000313|EMBL:CEO86940.1}; DE Flags: Fragment; GN Name=Tet1 {ECO:0000313|EMBL:CEO86940.1, ECO:0000313|MGI:MGI:1098693}; OS Mus musculus (Mouse). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; OC Muroidea; Muridae; Murinae; Mus; Mus. OX NCBI_TaxID=10090 {ECO:0000313|EMBL:CEO86940.1}; RN [1] {ECO:0000313|EMBL:CEO86940.1} RP NUCLEOTIDE SEQUENCE. RC STRAIN=C57BL/6x129/sv {ECO:0000313|EMBL:CEO86940.1}; RC TISSUE=Embryonic Stem cells {ECO:0000313|EMBL:CEO86940.1}; RA Sohni A., Bartoccetti M., Khoueiry R., Spans L., Vande Velde J., RA De Troyer L., Pulakanti K., Claessens F., Rao S., Koh K.; RT "Dynamic switching of active promoter and enhancer domains regulates RT Tet1 and Tet2 expression during cell state transitions between RT pluripotency and differentiation."; RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; LN810030; CEO86940.1; -; mRNA. DR EMBL; LN810032; CEO86942.1; -; mRNA. DR UniGene; Mm.17774; -. DR MGI; MGI:1098693; Tet1. DR GO; GO:0005634; C:nucleus; IDA:MGI. DR GO; GO:0005506; F:iron ion binding; ISO:MGI. DR GO; GO:0070579; F:methylcytosine dioxygenase activity; ISO:MGI. DR GO; GO:0043566; F:structure-specific DNA binding; ISO:MGI. DR GO; GO:0080111; P:DNA demethylation; IDA:MGI. DR GO; GO:0001826; P:inner cell mass cell differentiation; IMP:MGI. DR GO; GO:0090310; P:negative regulation of methylation-dependent chromatin silencing; ISO:MGI. DR GO; GO:0055114; P:oxidation-reduction process; ISO:GOC. DR GO; GO:0044030; P:regulation of DNA methylation; IMP:MGI. DR GO; GO:2000653; P:regulation of genetic imprinting; IMP:MGI. PE 2: Evidence at transcript level; KW Dioxygenase {ECO:0000313|EMBL:CEO86940.1}; KW Oxidoreductase {ECO:0000313|EMBL:CEO86940.1}. FT NON_TER 63 63 {ECO:0000313|EMBL:CEO86940.1}. SQ SEQUENCE 63 AA; 7064 MW; 15248500924FF71D CRC64; MTLCPASLHL YLLCSHVSVP PRKAFQISQN KATEKERHPD EDKNIKAGCQ TWGISEGSEP RKT //