ID A0A0B7J4R2_PHOPO Unreviewed; 511 AA. AC A0A0B7J4R2; DT 01-APR-2015, integrated into UniProtKB/TrEMBL. DT 01-APR-2015, sequence version 1. DT 11-MAY-2016, entry version 9. DE RecName: Full=UDP-N-acetylmuramyl-tripeptide synthetase {ECO:0000256|SAAS:SAAS00085409}; DE EC=6.3.2.- {ECO:0000256|SAAS:SAAS00276926}; GN Name=murE {ECO:0000313|EMBL:CEO38066.1}; GN ORFNames=PPBDW_I20078 {ECO:0000313|EMBL:CEO38066.1}; OS Photobacterium phosphoreum ANT-2200. OC Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales; OC Vibrionaceae; Photobacterium. OX NCBI_TaxID=1454202 {ECO:0000313|EMBL:CEO38066.1, ECO:0000313|Proteomes:UP000019762}; RN [1] {ECO:0000313|EMBL:CEO38066.1, ECO:0000313|Proteomes:UP000019762} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=ANT220 {ECO:0000313|Proteomes:UP000019762}; RA Genoscope - CEA; RL Submitted (DEC-2014) to the EMBL/GenBank/DDBJ databases. CC -!- PATHWAY: Cell wall biogenesis; peptidoglycan biosynthesis. CC {ECO:0000256|RuleBase:RU004135, ECO:0000256|SAAS:SAAS00085391}. CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|RuleBase:RU004135, CC ECO:0000256|SAAS:SAAS00085486}. CC -!- SIMILARITY: Belongs to the MurCDEF family. MurE subfamily. CC {ECO:0000256|SAAS:SAAS00569976}. CC -!- CAUTION: The sequence shown here is derived from an CC EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is CC preliminary data. {ECO:0000313|EMBL:CEO38066.1}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; CCAR020000004; CEO38066.1; -; Genomic_DNA. DR EnsemblBacteria; CEO38066; CEO38066; PPBDW_I20078. DR UniPathway; UPA00219; -. DR Proteomes; UP000019762; Unassembled WGS sequence. DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. DR GO; GO:0016881; F:acid-amino acid ligase activity; IEA:InterPro. DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW. DR GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW. DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW. DR GO; GO:0071555; P:cell wall organization; IEA:UniProtKB-KW. DR GO; GO:0009252; P:peptidoglycan biosynthetic process; IEA:UniProtKB-UniPathway. DR GO; GO:0008360; P:regulation of cell shape; IEA:UniProtKB-KW. DR Gene3D; 3.40.1190.10; -; 1. DR Gene3D; 3.40.1390.10; -; 1. DR Gene3D; 3.90.190.20; -; 1. DR HAMAP; MF_00208; MurE; 1. DR InterPro; IPR004101; Mur_ligase_C. DR InterPro; IPR013221; Mur_ligase_cen. DR InterPro; IPR000713; Mur_ligase_N. DR InterPro; IPR005761; UDP-N-AcMur-Glu-dNH2Pim_ligase. DR Pfam; PF01225; Mur_ligase; 1. DR Pfam; PF02875; Mur_ligase_C; 1. DR Pfam; PF08245; Mur_ligase_M; 1. DR SUPFAM; SSF53244; SSF53244; 1. DR SUPFAM; SSF53623; SSF53623; 1. DR SUPFAM; SSF63418; SSF63418; 1. DR TIGRFAMs; TIGR01085; murE; 1. PE 3: Inferred from homology; KW ATP-binding {ECO:0000256|SAAS:SAAS00459289}; KW Cell cycle {ECO:0000256|RuleBase:RU004135, KW ECO:0000256|SAAS:SAAS00459322}; KW Cell division {ECO:0000256|RuleBase:RU004135, KW ECO:0000256|SAAS:SAAS00459379}; KW Cell shape {ECO:0000256|RuleBase:RU004135, KW ECO:0000256|SAAS:SAAS00459388}; KW Cell wall biogenesis/degradation {ECO:0000256|RuleBase:RU004135, KW ECO:0000256|SAAS:SAAS00459257}; KW Complete proteome {ECO:0000313|Proteomes:UP000019762}; KW Cytoplasm {ECO:0000256|SAAS:SAAS00459408}; KW Ligase {ECO:0000256|SAAS:SAAS00459363, ECO:0000313|EMBL:CEO38066.1}; KW Nucleotide-binding {ECO:0000256|SAAS:SAAS00459299}; KW Peptidoglycan synthesis {ECO:0000256|RuleBase:RU004135, KW ECO:0000256|SAAS:SAAS00459442}. FT DOMAIN 38 116 Mur_ligase. {ECO:0000259|Pfam:PF01225}. FT DOMAIN 128 332 Mur_ligase_M. {ECO:0000259|Pfam:PF08245}. FT DOMAIN 355 441 Mur_ligase_C. {ECO:0000259|Pfam:PF02875}. SQ SEQUENCE 511 AA; 54343 MW; 57C93013B58225D4 CRC64; MSVIMALVKQ EVQLGALLAP WLTAKNVPAE YAQLLLTTMT LDSRQVTAGC LFAAVNGHTV DGRRFIANAI AAGASAIVAE AEGVASDGEI QFQDGIIIIY LHHLGHKLSA IAGRFYAEPD SKLKLYAVTG TNGKTTISQL LAQWADLIGY RAGVMGTTGN GLLTDLQPAA NTTGSAIEVQ QTLAELVTQG ANFAAMEVSS HGLVQGRVSA LHFVASIFTN LSRDHLDYHG DMAHYAAAKK SLFTEHDSGV AVINADDAIG QQWLADLPQA VAVAMNAEAV VAHSGPKLWA TAVDFSTQGV TICFESSWGN GNFTAPLVGS FNATNLLLAL ATLLVSGHSL PQLLAVAPRL QAVIGRMEVF QAPQADKAMM VVDYAHTPDA LDKALQALRV HCDGQLWCLF GCGGDRDSGK RPMMAAIAEQ YADHIILVDD NPRSEDPQQI MLDMQAGLTV ATAATIIHDR AQACAYALTH AKANDIILVA GKGHEDYQIL ADRTIHYSDR ETVAALFREL P //