ID A0A0B5KPZ3_9HIV1 Unreviewed; 192 AA. AC A0A0B5KPZ3; DT 01-APR-2015, integrated into UniProtKB/TrEMBL. DT 01-APR-2015, sequence version 1. DT 22-NOV-2017, entry version 10. DE RecName: Full=Virion infectivity factor {ECO:0000256|RuleBase:RU003341}; GN Name=vif {ECO:0000313|EMBL:AJG38616.1}; OS Human immunodeficiency virus 1. OC Viruses; Retro-transcribing viruses; Retroviridae; Orthoretrovirinae; OC Lentivirus; Primate lentivirus group. OX NCBI_TaxID=11676 {ECO:0000313|EMBL:AJG38616.1, ECO:0000313|Proteomes:UP000101665}; OH NCBI_TaxID=9606; Homo sapiens (Human). RN [1] {ECO:0000313|EMBL:AJG38616.1, ECO:0000313|Proteomes:UP000101665} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=R463MPL_I32 {ECO:0000313|EMBL:AJG38616.1}; RX PubMed=25569444; RA Yue L., Pfafferott K.J., Baalwa J., Conrod K., Dong C.C., Chui C., RA Rong R., Claiborne D.T., Prince J.L., Tang J., Ribeiro R.M., RA Cormier E., Hahn B.H., Perelson A.S., Shaw G.M., Karita E., RA Gilmour J., Goepfert P., Derdeyn C.A., Allen S.A., Borrow P., RA Hunter E.; RT "Transmitted Virus Fitness and Host T Cell Responses Collectively RT Define Divergent Infection Outcomes in Two HIV-1 Recipients."; RL PLoS Pathog. 11:E1004565-E1004565(2015). CC -!- SUBCELLULAR LOCATION: Host cell membrane CC {ECO:0000256|SAAS:SAAS00594051}; Peripheral membrane protein CC {ECO:0000256|SAAS:SAAS00594051}; Cytoplasmic side CC {ECO:0000256|SAAS:SAAS00594051}. CC -!- SUBCELLULAR LOCATION: Host cytoplasm CC {ECO:0000256|RuleBase:RU003341}. Host cell membrane CC {ECO:0000256|RuleBase:RU003341}; Peripheral membrane protein CC {ECO:0000256|RuleBase:RU003341}; Cytoplasmic side CC {ECO:0000256|RuleBase:RU003341}. Virion CC {ECO:0000256|RuleBase:RU003341}. Note=In the cytoplasm, seems to CC colocalize with intermediate filament vimentin. A fraction is CC associated with the cytoplasmic side of cellular membranes, CC presumably via the interaction with Pr55Gag precursor. CC {ECO:0000256|RuleBase:RU003341}. CC -!- SUBCELLULAR LOCATION: Virion {ECO:0000256|SAAS:SAAS00594062}. CC -!- SIMILARITY: Belongs to the primate lentivirus group Vif protein CC family. {ECO:0000256|RuleBase:RU003341, CC ECO:0000256|SAAS:SAAS00594061}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; KP223781; AJG38616.1; -; Genomic_RNA. DR Proteomes; UP000101665; Genome. DR GO; GO:0030430; C:host cell cytoplasm; IEA:UniProtKB-SubCell. DR GO; GO:0020002; C:host cell plasma membrane; IEA:UniProtKB-SubCell. DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW. DR GO; GO:0019012; C:virion; IEA:UniProtKB-SubCell. DR GO; GO:0019058; P:viral life cycle; IEA:InterPro. DR InterPro; IPR000475; Viral_infect. DR Pfam; PF00559; Vif; 1. DR PRINTS; PR00349; VIRIONINFFCT. PE 3: Inferred from homology; KW Complete proteome {ECO:0000313|Proteomes:UP000101665}; KW Host cell membrane {ECO:0000256|SAAS:SAAS00135760}; KW Host cytoplasm {ECO:0000256|SAAS:SAAS00487388}; KW Host membrane {ECO:0000256|SAAS:SAAS00487340}; KW Host-virus interaction {ECO:0000256|SAAS:SAAS00487339}; KW Membrane {ECO:0000256|SAAS:SAAS00135657}; KW Ubl conjugation pathway {ECO:0000256|SAAS:SAAS00487332}; KW Virion {ECO:0000256|SAAS:SAAS00487311}. SQ SEQUENCE 192 AA; 22769 MW; 1B52F005D0341A48 CRC64; MENRWQVMIV WQVDRMRIRT WNSLVKYHMY RSKKAKRWFY RHHYESNHPK VSSEVHIPLG EARLVVRTYW GLHTGERDWQ LGHGVSIEWR LRRYNTQIDP ELADQLIHLH YFACFSESAI RKAILGQVVS PSCEYQAGHN KVGSLQYLAL KALVTPTREK PPLPSVRKLT EDRWNKPQKT RGHRGSHTMN GC //