ID A0A0B4KHX5_DROME Unreviewed; 1338 AA. AC A0A0B4KHX5; DT 01-APR-2015, integrated into UniProtKB/TrEMBL. DT 01-APR-2015, sequence version 1. DT 03-JUL-2019, entry version 39. DE SubName: Full=Chaoptin, isoform D {ECO:0000313|EMBL:AGB96516.1}; GN Name=chp {ECO:0000313|EMBL:AGB96516.1, GN ECO:0000313|FlyBase:FBgn0267435}; GN Synonyms=24B10 {ECO:0000313|EMBL:AGB96516.1}, 516 GN {ECO:0000313|EMBL:AGB96516.1}, BSH {ECO:0000313|EMBL:AGB96516.1}, GN CG1744 {ECO:0000313|EMBL:AGB96516.1}, Chaoptin GN {ECO:0000313|EMBL:AGB96516.1}, CHP {ECO:0000313|EMBL:AGB96516.1}, Chp GN {ECO:0000313|EMBL:AGB96516.1}, CT5040 {ECO:0000313|EMBL:AGB96516.1}, GN Dmel\CG1744 {ECO:0000313|EMBL:AGB96516.1}, idl-A GN {ECO:0000313|EMBL:AGB96516.1}, MAb 24B10 GN {ECO:0000313|EMBL:AGB96516.1}, mAb 24B10 GN {ECO:0000313|EMBL:AGB96516.1}, MAb24B10 {ECO:0000313|EMBL:AGB96516.1}, GN Mab24B10 {ECO:0000313|EMBL:AGB96516.1}, mAB24B10 GN {ECO:0000313|EMBL:AGB96516.1}, mAb24B10 {ECO:0000313|EMBL:AGB96516.1}, GN Nsp {ECO:0000313|EMBL:AGB96516.1}; GN ORFNames=CG1744 {ECO:0000313|FlyBase:FBgn0267435}, Dmel_CG1744 GN {ECO:0000313|EMBL:AGB96516.1}; OS Drosophila melanogaster (Fruit fly). OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; OC Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; OC Ephydroidea; Drosophilidae; Drosophila; Sophophora. OX NCBI_TaxID=7227 {ECO:0000313|EMBL:AGB96516.1, ECO:0000313|Proteomes:UP000000803}; RN [1] {ECO:0000313|EMBL:AGB96516.1, ECO:0000313|Proteomes:UP000000803} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803}; RX PubMed=10731132; DOI=10.1126/science.287.5461.2185; RA Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D., RA Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F., RA George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N., RA Sutton G.G., Wortman J.R., Yandell M.D., Zhang Q., Chen L.X., RA Brandon R.C., Rogers Y.H., Blazej R.G., Champe M., Pfeiffer B.D., RA Wan K.H., Doyle C., Baxter E.G., Helt G., Nelson C.R., Gabor G.L., RA Abril J.F., Agbayani A., An H.J., Andrews-Pfannkoch C., Baldwin D., RA Ballew R.M., Basu A., Baxendale J., Bayraktaroglu L., Beasley E.M., RA Beeson K.Y., Benos P.V., Berman B.P., Bhandari D., Bolshakov S., RA Borkova D., Botchan M.R., Bouck J., Brokstein P., Brottier P., RA Burtis K.C., Busam D.A., Butler H., Cadieu E., Center A., Chandra I., RA Cherry J.M., Cawley S., Dahlke C., Davenport L.B., Davies P., RA de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I., Dietz S.M., RA Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C., Dunn P., RA Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S., Fleischmann W., RA Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M., Glasser K., RA Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M., RA Harris N.L., Harvey D., Heiman T.J., Hernandez J.R., Houck J., RA Hostin D., Houston K.A., Howland T.J., Wei M.H., Ibegwam C., RA Jalali M., Kalush F., Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., RA Kimmel B.E., Kodira C.D., Kraft C., Kravitz S., Kulp D., Lai Z., RA Lasko P., Lei Y., Levitsky A.A., Li J., Li Z., Liang Y., Lin X., RA Liu X., Mattei B., McIntosh T.C., McLeod M.P., McPherson D., RA Merkulov G., Milshina N.V., Mobarry C., Morris J., Moshrefi A., RA Mount S.M., Moy M., Murphy B., Murphy L., Muzny D.M., Nelson D.L., RA Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R., Pacleb J.M., RA Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V., Reese M.G., RA Reinert K., Remington K., Saunders R.D., Scheeler F., Shen H., RA Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T., RA Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., RA Svirskas R., Tector C., Turner R., Venter E., Wang A.H., Wang X., RA Wang Z.Y., Wassarman D.A., Weinstock G.M., Weissenbach J., RA Williams S.M., WoodageT, Worley K.C., Wu D., Yang S., Yao Q.A., Ye J., RA Yeh R.F., Zaveri J.S., Zhan M., Zhang G., Zhao Q., Zheng L., RA Zheng X.H., Zhong F.N., Zhong W., Zhou X., Zhu S., Zhu X., Smith H.O., RA Gibbs R.A., Myers E.W., Rubin G.M., Venter J.C.; RT "The genome sequence of Drosophila melanogaster."; RL Science 287:2185-2195(2000). RN [2] {ECO:0000313|EMBL:AGB96516.1, ECO:0000313|Proteomes:UP000000803} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803}; RX PubMed=12537568; RA Celniker S.E., Wheeler D.A., Kronmiller B., Carlson J.W., Halpern A., RA Patel S., Adams M., Champe M., Dugan S.P., Frise E., Hodgson A., RA George R.A., Hoskins R.A., Laverty T., Muzny D.M., Nelson C.R., RA Pacleb J.M., Park S., Pfeiffer B.D., Richards S., Sodergren E.J., RA Svirskas R., Tabor P.E., Wan K., Stapleton M., Sutton G.G., Venter C., RA Weinstock G., Scherer S.E., Myers E.W., Gibbs R.A., Rubin G.M.; RT "Finishing a whole-genome shotgun: release 3 of the Drosophila RT melanogaster euchromatic genome sequence."; RL Genome Biol. 3:RESEARCH0079-RESEARCH0079(2002). RN [3] {ECO:0000313|EMBL:AGB96516.1, ECO:0000313|Proteomes:UP000000803} RP GENOME REANNOTATION. RC STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803}; RX PubMed=12537572; DOI=10.1186/gb-2002-3-12-research0083; RA Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S., RA Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E., RA Smith C.D., Tupy J.L., Whitfied E.J., Bayraktaroglu L., Berman B.P., RA Bettencourt B.R., Celniker S.E., de Grey A.D., Drysdale R.A., RA Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q., RA Stapleton M., Yamada C., Ashburner M., Gelbart W.M., Rubin G.M., RA Lewis S.E.; RT "Annotation of the Drosophila melanogaster euchromatic genome: a RT systematic review."; RL Genome Biol. 3:RESEARCH0083.1-RESEARCH0083.22(2002). RN [4] {ECO:0000313|EMBL:AGB96516.1, ECO:0000313|Proteomes:UP000000803} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803}; RX PubMed=12537573; RA Kaminker J.S., Bergman C.M., Kronmiller B., Carlson J., Svirskas R., RA Patel S., Frise E., Wheeler D.A., Lewis S.E., Rubin G.M., RA Ashburner M., Celniker S.E.; RT "The transposable elements of the Drosophila melanogaster euchromatin: RT a genomics perspective."; RL Genome Biol. 3:RESEARCH0084-RESEARCH0084(2002). RN [5] {ECO:0000313|EMBL:AGB96516.1, ECO:0000313|Proteomes:UP000000803} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803}; RX PubMed=12537574; RA Hoskins R.A., Smith C.D., Carlson J.W., Carvalho A.B., Halpern A., RA Kaminker J.S., Kennedy C., Mungall C.J., Sullivan B.A., Sutton G.G., RA Yasuhara J.C., Wakimoto B.T., Myers E.W., Celniker S.E., Rubin G.M., RA Karpen G.H.; RT "Heterochromatic sequences in a Drosophila whole-genome shotgun RT assembly."; RL Genome Biol. 3:RESEARCH0085-RESEARCH0085(2002). RN [6] {ECO:0000313|EMBL:AGB96516.1, ECO:0000313|Proteomes:UP000000803} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803}; RX PubMed=16110336; DOI=10.1371/journal.pcbi.0010022; RA Quesneville H., Bergman C.M., Andrieu O., Autard D., Nouaud D., RA Ashburner M., Anxolabehere D.; RT "Combined evidence annotation of transposable elements in genome RT sequences."; RL PLoS Comput. Biol. 1:166-175(2005). RN [7] {ECO:0000313|EMBL:AGB96516.1, ECO:0000313|Proteomes:UP000000803} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803}; RX PubMed=17569856; DOI=10.1126/science.1139815; RA Smith C.D., Shu S., Mungall C.J., Karpen G.H.; RT "The Release 5.1 annotation of Drosophila melanogaster RT heterochromatin."; RL Science 316:1586-1591(2007). RN [8] {ECO:0000313|EMBL:AGB96516.1, ECO:0000313|Proteomes:UP000000803} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803}; RX PubMed=17569867; DOI=10.1126/science.1139816; RA Hoskins R.A., Carlson J.W., Kennedy C., Acevedo D., Evans-Holm M., RA Frise E., Wan K.H., Park S., Mendez-Lago M., Rossi F., Villasante A., RA Dimitri P., Karpen G.H., Celniker S.E.; RT "Sequence finishing and mapping of Drosophila melanogaster RT heterochromatin."; RL Science 316:1625-1628(2007). CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AE014297; AGB96516.1; -; Genomic_DNA. DR RefSeq; NP_001263137.1; NM_001276208.1. DR EnsemblMetazoa; FBtr0330101; FBpp0303134; FBgn0267435. DR GeneID; 43690; -. DR CTD; 43690; -. DR FlyBase; FBgn0267435; chp. DR eggNOG; KOG0619; Eukaryota. DR eggNOG; COG4886; LUCA. DR GeneTree; ENSGT00940000164586; -. DR ChiTaRS; chp; fly. DR GenomeRNAi; 43690; -. DR Proteomes; UP000000803; Chromosome 3R. DR ExpressionAtlas; A0A0B4KHX5; baseline and differential. DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW. DR Gene3D; 3.80.10.10; -; 7. DR InterPro; IPR000225; Armadillo. DR InterPro; IPR001611; Leu-rich_rpt. DR InterPro; IPR003591; Leu-rich_rpt_typical-subtyp. DR InterPro; IPR032675; LRR_dom_sf. DR Pfam; PF13855; LRR_8; 9. DR SMART; SM00369; LRR_TYP; 27. DR PROSITE; PS50176; ARM_REPEAT; 1. DR PROSITE; PS51450; LRR; 29. PE 1: Evidence at protein level; KW Complete proteome {ECO:0000313|Proteomes:UP000000803}; KW Membrane {ECO:0000256|SAM:Phobius}; KW Proteomics identification {ECO:0000213|PeptideAtlas:A0A0B4KHX5}; KW Reference proteome {ECO:0000313|Proteomes:UP000000803}; KW Transmembrane {ECO:0000256|SAM:Phobius}; KW Transmembrane helix {ECO:0000256|SAM:Phobius}. FT TRANSMEM 5 26 Helical. {ECO:0000256|SAM:Phobius}. FT TRANSMEM 1297 1319 Helical. {ECO:0000256|SAM:Phobius}. FT REPEAT 222 251 ARM. {ECO:0000256|PROSITE-ProRule: FT PRU00259}. SQ SEQUENCE 1338 AA; 154738 MW; 403BAD5891C50981 CRC64; MGLEFFFKFG YAFLTITLMI MIWMSLARAS MFDREMEETH YPPCTYNVMC TCSKSSTDLG IVHCKNVPFP ALPRMVNQSK VFMLHMENTG LREIEPYFLQ STGMYRLKIS GNHLTEIPDD AFTGLERSLW ELILPQNDLV EIPSKSLRHL QKLRHLDLGY NHITHIQHDS FRGLEDSLQT LILRENCISQ LMSHSFSGLL ILETLDLSGN NLFEIDPNVF VDGMPRLTRL LLTDNILSEI PYDALGPLKS LRTLDISHNV IWSLSGNETY EIKASTKLNL DNLHLEYNHI EVLPPNSFKY FDTVNRTFFD GNPIHTLRED AFKPARIREI YMRYCGLTNI SPVAFDSLVN SLQILDLSGN NLTKLHHKLF NNFDVLRVIS MRDNKIKIQK PTETFNAVHY TLLKLDLSGD RNDPTNLQTL RKMRNMRSLS ISRLGSSSVG PEDFKDFGVE LEDLQITRAS LSGIQSHAFK HVRGLKRLDF SENGISSIEN DAFHEIGHSL ISLKMSHGYS GSALPAEPLR HLTSLQELDF SNNHISSMSD TSFHFLKNLR LLELHDNRIE QVLKGTFQGD IHSKLEEISL RFNHLTSISQ HTFFDLEALR KLHLDDNKID KIERRAFMNL DELEYLSLRG NKINNLADES FQNLPKLEIL DMAFNQLPNF NFDYFDQVGT LSNLNVNVSH NQIRQLMYNS SWSGRNEHGG MYHSNIKILD LSHNNISIIH PGYFRPAEIS LTHLHLGYNS LMNTTRDVFG NMPHLQWLDL SYNWIHELDF DAFKNTKQLQ LVFFGHNYLS DIPQDIFKPV QGLRIVDFSH NHLRGLPDNL FYNGGMEKLD VSHNMMLKIP SSSLSSLAAL TLCELHLSNN FISTIHSMDL SNKFRSLRYL DISYNYLLRI DDAVFATMPK LAVLDLSHNR DLKVMDKSFM GLENSLIKLG LENISLSTVP EIRLKYLREF RLGYNELPSI PQELAHNMSN LRMLDLSNND LTNVPLMTQA LPHLRRLMLS GNPITSLNNN SFDGVNEDLE MLDISNFRLH YFEYGCLDSL PHLRSLKLTA YSHLEHFNIP HLLRHHYNIR QLWIEAPQPF TRIVKKGSGP TQEMQTLQLG NPTDLQREME GHLPSKLTNI TFSGPQFTNL NERILRGMRS PYLYMQLFNT SLQALPPNFF KYMGRVRNIS LDIRYHNRNL KKIPNPNTGA VPYLPNSVFL TDLKMSHTDL NCDCDLGWVE FWQRKRRQYI CSSQTWTDTV FRTFMNSPCQ VYGRHNCDEH DDDLRETRCE NKGGQQLMEA LKFDLECGWD NANCREAAFV VVMVCVAMVF WMXLLHFTYK TSTDFYTILE QVYGRQVI //