ID A0A0B4KHP5_DROME Unreviewed; 1430 AA. AC A0A0B4KHP5; DT 01-APR-2015, integrated into UniProtKB/TrEMBL. DT 01-APR-2015, sequence version 1. DT 08-MAY-2019, entry version 37. DE SubName: Full=Cap-n-collar, isoform O {ECO:0000313|EMBL:AGB96244.1}; GN Name=cnc {ECO:0000313|EMBL:AGB96244.1, GN ECO:0000313|FlyBase:FBgn0262975}; GN Synonyms=5134 {ECO:0000313|EMBL:AGB96244.1}, anon-WO0153538.6 GN {ECO:0000313|EMBL:AGB96244.1}, anon-WO0153538.7 GN {ECO:0000313|EMBL:AGB96244.1}, BcDNA:RE05559 GN {ECO:0000313|EMBL:AGB96244.1}, CG13826 {ECO:0000313|EMBL:AGB96244.1}, GN CG17894 {ECO:0000313|EMBL:AGB96244.1}, CG4566 GN {ECO:0000313|EMBL:AGB96244.1}, CG4578 {ECO:0000313|EMBL:AGB96244.1}, GN CNC {ECO:0000313|EMBL:AGB96244.1}, CnC {ECO:0000313|EMBL:AGB96244.1}, GN Cnc {ECO:0000313|EMBL:AGB96244.1}, cnc-C GN {ECO:0000313|EMBL:AGB96244.1}, CNC_DROME GN {ECO:0000313|EMBL:AGB96244.1}, CncC {ECO:0000313|EMBL:AGB96244.1}, GN DM12 {ECO:0000313|EMBL:AGB96244.1}, Dmel\CG43286 GN {ECO:0000313|EMBL:AGB96244.1}, dNrf2 {ECO:0000313|EMBL:AGB96244.1}, GN l(3)03921 {ECO:0000313|EMBL:AGB96244.1}, l(3)j5E7 GN {ECO:0000313|EMBL:AGB96244.1}, Nrf2 {ECO:0000313|EMBL:AGB96244.1}; GN ORFNames=CG43286 {ECO:0000313|EMBL:AGB96244.1, GN ECO:0000313|FlyBase:FBgn0262975}, Dmel_CG43286 GN {ECO:0000313|EMBL:AGB96244.1}; OS Drosophila melanogaster (Fruit fly). OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; OC Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; OC Ephydroidea; Drosophilidae; Drosophila; Sophophora. OX NCBI_TaxID=7227 {ECO:0000313|EMBL:AGB96244.1, ECO:0000313|Proteomes:UP000000803}; RN [1] {ECO:0000313|EMBL:AGB96244.1, ECO:0000313|Proteomes:UP000000803} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803}; RX PubMed=10731132; DOI=10.1126/science.287.5461.2185; RA Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D., RA Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F., RA George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N., RA Sutton G.G., Wortman J.R., Yandell M.D., Zhang Q., Chen L.X., RA Brandon R.C., Rogers Y.H., Blazej R.G., Champe M., Pfeiffer B.D., RA Wan K.H., Doyle C., Baxter E.G., Helt G., Nelson C.R., Gabor G.L., RA Abril J.F., Agbayani A., An H.J., Andrews-Pfannkoch C., Baldwin D., RA Ballew R.M., Basu A., Baxendale J., Bayraktaroglu L., Beasley E.M., RA Beeson K.Y., Benos P.V., Berman B.P., Bhandari D., Bolshakov S., RA Borkova D., Botchan M.R., Bouck J., Brokstein P., Brottier P., RA Burtis K.C., Busam D.A., Butler H., Cadieu E., Center A., Chandra I., RA Cherry J.M., Cawley S., Dahlke C., Davenport L.B., Davies P., RA de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I., Dietz S.M., RA Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C., Dunn P., RA Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S., Fleischmann W., RA Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M., Glasser K., RA Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M., RA Harris N.L., Harvey D., Heiman T.J., Hernandez J.R., Houck J., RA Hostin D., Houston K.A., Howland T.J., Wei M.H., Ibegwam C., RA Jalali M., Kalush F., Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., RA Kimmel B.E., Kodira C.D., Kraft C., Kravitz S., Kulp D., Lai Z., RA Lasko P., Lei Y., Levitsky A.A., Li J., Li Z., Liang Y., Lin X., RA Liu X., Mattei B., McIntosh T.C., McLeod M.P., McPherson D., RA Merkulov G., Milshina N.V., Mobarry C., Morris J., Moshrefi A., RA Mount S.M., Moy M., Murphy B., Murphy L., Muzny D.M., Nelson D.L., RA Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R., Pacleb J.M., RA Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V., Reese M.G., RA Reinert K., Remington K., Saunders R.D., Scheeler F., Shen H., RA Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T., RA Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., RA Svirskas R., Tector C., Turner R., Venter E., Wang A.H., Wang X., RA Wang Z.Y., Wassarman D.A., Weinstock G.M., Weissenbach J., RA Williams S.M., WoodageT, Worley K.C., Wu D., Yang S., Yao Q.A., Ye J., RA Yeh R.F., Zaveri J.S., Zhan M., Zhang G., Zhao Q., Zheng L., RA Zheng X.H., Zhong F.N., Zhong W., Zhou X., Zhu S., Zhu X., Smith H.O., RA Gibbs R.A., Myers E.W., Rubin G.M., Venter J.C.; RT "The genome sequence of Drosophila melanogaster."; RL Science 287:2185-2195(2000). RN [2] {ECO:0000313|EMBL:AGB96244.1, ECO:0000313|Proteomes:UP000000803} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803}; RX PubMed=12537568; RA Celniker S.E., Wheeler D.A., Kronmiller B., Carlson J.W., Halpern A., RA Patel S., Adams M., Champe M., Dugan S.P., Frise E., Hodgson A., RA George R.A., Hoskins R.A., Laverty T., Muzny D.M., Nelson C.R., RA Pacleb J.M., Park S., Pfeiffer B.D., Richards S., Sodergren E.J., RA Svirskas R., Tabor P.E., Wan K., Stapleton M., Sutton G.G., Venter C., RA Weinstock G., Scherer S.E., Myers E.W., Gibbs R.A., Rubin G.M.; RT "Finishing a whole-genome shotgun: release 3 of the Drosophila RT melanogaster euchromatic genome sequence."; RL Genome Biol. 3:RESEARCH0079-RESEARCH0079(2002). RN [3] {ECO:0000313|EMBL:AGB96244.1, ECO:0000313|Proteomes:UP000000803} RP GENOME REANNOTATION. RC STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803}; RX PubMed=12537572; DOI=10.1186/gb-2002-3-12-research0083; RA Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S., RA Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E., RA Smith C.D., Tupy J.L., Whitfied E.J., Bayraktaroglu L., Berman B.P., RA Bettencourt B.R., Celniker S.E., de Grey A.D., Drysdale R.A., RA Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q., RA Stapleton M., Yamada C., Ashburner M., Gelbart W.M., Rubin G.M., RA Lewis S.E.; RT "Annotation of the Drosophila melanogaster euchromatic genome: a RT systematic review."; RL Genome Biol. 3:RESEARCH0083.1-RESEARCH0083.22(2002). RN [4] {ECO:0000313|EMBL:AGB96244.1, ECO:0000313|Proteomes:UP000000803} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803}; RX PubMed=12537573; RA Kaminker J.S., Bergman C.M., Kronmiller B., Carlson J., Svirskas R., RA Patel S., Frise E., Wheeler D.A., Lewis S.E., Rubin G.M., RA Ashburner M., Celniker S.E.; RT "The transposable elements of the Drosophila melanogaster euchromatin: RT a genomics perspective."; RL Genome Biol. 3:RESEARCH0084.1-RESEARCH0084.20(2002). RN [5] {ECO:0000313|EMBL:AGB96244.1, ECO:0000313|Proteomes:UP000000803} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803}; RX PubMed=12537574; RA Hoskins R.A., Smith C.D., Carlson J.W., Carvalho A.B., Halpern A., RA Kaminker J.S., Kennedy C., Mungall C.J., Sullivan B.A., Sutton G.G., RA Yasuhara J.C., Wakimoto B.T., Myers E.W., Celniker S.E., Rubin G.M., RA Karpen G.H.; RT "Heterochromatic sequences in a Drosophila whole-genome shotgun RT assembly."; RL Genome Biol. 3:RESEARCH0085-RESEARCH0085(2002). RN [6] {ECO:0000313|EMBL:AGB96244.1, ECO:0000313|Proteomes:UP000000803} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803}; RX PubMed=16110336; DOI=10.1371/journal.pcbi.0010022; RA Quesneville H., Bergman C.M., Andrieu O., Autard D., Nouaud D., RA Ashburner M., Anxolabehere D.; RT "Combined evidence annotation of transposable elements in genome RT sequences."; RL PLoS Comput. Biol. 1:166-175(2005). RN [7] {ECO:0000313|EMBL:AGB96244.1, ECO:0000313|Proteomes:UP000000803} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803}; RX PubMed=17569856; DOI=10.1126/science.1139815; RA Smith C.D., Shu S., Mungall C.J., Karpen G.H.; RT "The Release 5.1 annotation of Drosophila melanogaster RT heterochromatin."; RL Science 316:1586-1591(2007). RN [8] {ECO:0000313|EMBL:AGB96244.1, ECO:0000313|Proteomes:UP000000803} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803}; RX PubMed=17569867; DOI=10.1126/science.1139816; RA Hoskins R.A., Carlson J.W., Kennedy C., Acevedo D., Evans-Holm M., RA Frise E., Wan K.H., Park S., Mendez-Lago M., Rossi F., Villasante A., RA Dimitri P., Karpen G.H., Celniker S.E.; RT "Sequence finishing and mapping of Drosophila melanogaster RT heterochromatin."; RL Science 316:1625-1628(2007). CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|SAAS:SAAS01109866}. CC -!- SIMILARITY: Belongs to the bZIP family. CC {ECO:0000256|SAAS:SAAS00810676}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AE014297; AGB96244.1; -; Genomic_DNA. DR RefSeq; NP_001262864.1; NM_001275935.1. DR EnsemblMetazoa; FBtr0330372; FBpp0303398; FBgn0262975. DR GeneID; 42743; -. DR CTD; 42743; -. DR FlyBase; FBgn0262975; cnc. DR eggNOG; KOG3863; Eukaryota. DR eggNOG; ENOG410ZGMS; LUCA. DR OMA; VPMIETQ; -. DR GenomeRNAi; 42743; -. DR Proteomes; UP000000803; Chromosome 3R. DR ExpressionAtlas; A0A0B4KHP5; baseline and differential. DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW. DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro. DR InterPro; IPR004827; bZIP. DR InterPro; IPR004826; bZIP_Maf. DR InterPro; IPR008917; TF_DNA-bd_sf. DR Pfam; PF03131; bZIP_Maf; 1. DR SMART; SM00338; BRLZ; 1. DR SUPFAM; SSF47454; SSF47454; 1. DR PROSITE; PS50217; BZIP; 1. DR PROSITE; PS00036; BZIP_BASIC; 1. PE 3: Inferred from homology; KW Coiled coil {ECO:0000256|SAM:Coils}; KW Complete proteome {ECO:0000313|Proteomes:UP000000803}; KW DNA-binding {ECO:0000256|SAAS:SAAS00812580}; KW Nucleus {ECO:0000256|SAAS:SAAS01109505}; KW Reference proteome {ECO:0000313|Proteomes:UP000000803}; KW Signal {ECO:0000256|SAM:SignalP}; KW Transcription {ECO:0000256|SAAS:SAAS01002396}; KW Transcription regulation {ECO:0000256|SAAS:SAAS01001750}. FT SIGNAL 1 18 {ECO:0000256|SAM:SignalP}. FT CHAIN 19 1430 {ECO:0000256|SAM:SignalP}. FT /FTId=PRO_5002094263. FT DOMAIN 1195 1258 BZIP. {ECO:0000259|PROSITE:PS50217}. FT COILED 425 445 {ECO:0000256|SAM:Coils}. FT COILED 1220 1254 {ECO:0000256|SAM:Coils}. SQ SEQUENCE 1430 AA; 153324 MW; 1537AED82C02DBDA CRC64; MISNKKSYAM KMLQLALALS LLHYNPDYLL HRWDSQLELG THGDGWELEM LRTVHRLDMD HNPYGNRKGL SPRIEDLLNF DDPSLGGMAN GIGGCKLPPR FNGSTFVMNL HNTTGNSSVQ TAALQDVQST SAAATGGTMV VGTGGAPTSG GQTSGSALGE IHIDTASLDP GNANHSPLHP TSELDTFLTP HALQDQRSIW EQNLADLYDY NDLSLQTSPY ANLPLKDGQP QPSNSSHLDL SLAALLHGFT GGSGAPLSTA ALNDSTPHPR NLGSVTNNSA GRSDDGEESL YLGRLFGEDE DEDYEGELIG GVANACEVEG LTTDEPFGSN CFANEVEIGD DEEESEIAEV LYKQDVDLGF SLDQEAIINA SYASGNSAAT NVKSKPEDET KSSDPSISES SGFKDTDVNA ENEASAASVD DIEKLKALEE LQQDKDKNNE NQLEDITNEW NGIPFTIDNE TGEYIRLPLD ELLNDVLKLS EFPLQDDLSN DPVASTSQAA AAFNENQAQR IVSETGEDLL SGEGISSKQN RNEAKNKDND PEKADGDSFS VSDFEELQNS VGSPLFDLDE DAKKELDEML QSAVPSYHHP HPHHGHPHAH PHSHHHASMH HAHAHHAAAA AAAHQRAVQQ ANYGGGVGVG VGVGVGVGSG TGSAFQRQPA AGGFHHGHHQ GRMPRLNRSV SMERLQDFAT YFSPIPSMVG GVSDMSPYPH HYPGYSYQAS PSNGAPGTPG QHGQYGSGAN ATLQPPPPPP PPHHAAMLHH PNAALGDICP TGQPHYGHNL GSAVTSSMHL TNSSHEADGA AAAAAAYKVE HDLMYYGNTS SDINQTDGFI NSIFTDEDLH LMDMNESFCR MVDNSTSNNS SVLGLPSSGH VSNGSGSSAQ LGAGNPHGNQ ANGASGGVGS MSGSAVGAGA TGMTADLLAS GGAGAQGGAD RLDASSDSAV SSMGSERVPS LSDGEWGEGS DSAQDYHQGK YGGPYDFSYN NNSRLSTATR QPPVAQKKHQ LYGKRDPHKQ TPSALPPTAP PAAATAVQSQ SIKYEYDAGY ASSGMASGGI SEPGAMGPAL SKDYHHHQPY GMGASGSAFS GDYTVRPSPR TSQDLVQLNH TYSLPQGSGS LPRPQARDKK PLVATKTASK GASAGNSSSV GGNSSNLEEE HLTRDEKRAR SLNIPISVPD IINLPMDEFN ERLSKYDLSE NQLSLIRDIR RRGKNKVAAQ NCRKRKLDQI LTLEDEVNAV VKRKTQLNQD RDHLESERKR ISNKFAMLHR HVFQYLRDPE GNPCSPADYS LQQAADGSVY LLPREKSEGN NTATAASNAV SSASGGSLNG HVPTQAPMHS HQSHGMQAQH VVGGMSQQQQ QQSRLPPHLQ QQHHLQSQQQ QPGGQQQQQH RKEXKYLLRI AATKSWFTSF QRGQQHRSVQ QQQQQFDYRY DMMNNSYLYY //