ID A0A0B4KEH7_DROME Unreviewed; 2409 AA. AC A0A0B4KEH7; DT 01-APR-2015, integrated into UniProtKB/TrEMBL. DT 01-APR-2015, sequence version 1. DT 22-NOV-2017, entry version 27. DE SubName: Full=CAP, isoform Y {ECO:0000313|EMBL:AGB93393.1}; GN Name=CAP {ECO:0000313|EMBL:AGB93393.1, GN ECO:0000313|FlyBase:FBgn0033504}; GN ORFNames=CG18408 {ECO:0000313|FlyBase:FBgn0033504}, Dmel_CG18408 GN {ECO:0000313|EMBL:AGB93393.1}; OS Drosophila melanogaster (Fruit fly). OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; OC Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; OC Ephydroidea; Drosophilidae; Drosophila; Sophophora. OX NCBI_TaxID=7227 {ECO:0000313|EMBL:AGB93393.1, ECO:0000313|Proteomes:UP000000803}; RN [1] {ECO:0000313|EMBL:AGB93393.1, ECO:0000313|Proteomes:UP000000803} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803}; RX PubMed=10731132; DOI=10.1126/science.287.5461.2185; RA Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D., RA Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F., RA George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N., RA Sutton G.G., Wortman J.R., Yandell M.D., Zhang Q., Chen L.X., RA Brandon R.C., Rogers Y.H., Blazej R.G., Champe M., Pfeiffer B.D., RA Wan K.H., Doyle C., Baxter E.G., Helt G., Nelson C.R., Gabor G.L., RA Abril J.F., Agbayani A., An H.J., Andrews-Pfannkoch C., Baldwin D., RA Ballew R.M., Basu A., Baxendale J., Bayraktaroglu L., Beasley E.M., RA Beeson K.Y., Benos P.V., Berman B.P., Bhandari D., Bolshakov S., RA Borkova D., Botchan M.R., Bouck J., Brokstein P., Brottier P., RA Burtis K.C., Busam D.A., Butler H., Cadieu E., Center A., Chandra I., RA Cherry J.M., Cawley S., Dahlke C., Davenport L.B., Davies P., RA de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I., Dietz S.M., RA Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C., Dunn P., RA Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S., Fleischmann W., RA Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M., Glasser K., RA Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M., RA Harris N.L., Harvey D., Heiman T.J., Hernandez J.R., Houck J., RA Hostin D., Houston K.A., Howland T.J., Wei M.H., Ibegwam C., RA Jalali M., Kalush F., Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., RA Kimmel B.E., Kodira C.D., Kraft C., Kravitz S., Kulp D., Lai Z., RA Lasko P., Lei Y., Levitsky A.A., Li J., Li Z., Liang Y., Lin X., RA Liu X., Mattei B., McIntosh T.C., McLeod M.P., McPherson D., RA Merkulov G., Milshina N.V., Mobarry C., Morris J., Moshrefi A., RA Mount S.M., Moy M., Murphy B., Murphy L., Muzny D.M., Nelson D.L., RA Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R., Pacleb J.M., RA Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V., Reese M.G., RA Reinert K., Remington K., Saunders R.D., Scheeler F., Shen H., RA Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T., RA Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., RA Svirskas R., Tector C., Turner R., Venter E., Wang A.H., Wang X., RA Wang Z.Y., Wassarman D.A., Weinstock G.M., Weissenbach J., RA Williams S.M., WoodageT, Worley K.C., Wu D., Yang S., Yao Q.A., Ye J., RA Yeh R.F., Zaveri J.S., Zhan M., Zhang G., Zhao Q., Zheng L., RA Zheng X.H., Zhong F.N., Zhong W., Zhou X., Zhu S., Zhu X., Smith H.O., RA Gibbs R.A., Myers E.W., Rubin G.M., Venter J.C.; RT "The genome sequence of Drosophila melanogaster."; RL Science 287:2185-2195(2000). RN [2] {ECO:0000313|EMBL:AGB93393.1, ECO:0000313|Proteomes:UP000000803} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803}; RX PubMed=12537568; RA Celniker S.E., Wheeler D.A., Kronmiller B., Carlson J.W., Halpern A., RA Patel S., Adams M., Champe M., Dugan S.P., Frise E., Hodgson A., RA George R.A., Hoskins R.A., Laverty T., Muzny D.M., Nelson C.R., RA Pacleb J.M., Park S., Pfeiffer B.D., Richards S., Sodergren E.J., RA Svirskas R., Tabor P.E., Wan K., Stapleton M., Sutton G.G., Venter C., RA Weinstock G., Scherer S.E., Myers E.W., Gibbs R.A., Rubin G.M.; RT "Finishing a whole-genome shotgun: release 3 of the Drosophila RT melanogaster euchromatic genome sequence."; RL Genome Biol. 3:RESEARCH0079-RESEARCH0079(2002). RN [3] {ECO:0000313|EMBL:AGB93393.1, ECO:0000313|Proteomes:UP000000803} RP GENOME REANNOTATION. RC STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803}; RX PubMed=12537572; DOI=10.1186/gb-2002-3-12-research0083; RA Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S., RA Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E., RA Smith C.D., Tupy J.L., Whitfied E.J., Bayraktaroglu L., Berman B.P., RA Bettencourt B.R., Celniker S.E., de Grey A.D., Drysdale R.A., RA Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q., RA Stapleton M., Yamada C., Ashburner M., Gelbart W.M., Rubin G.M., RA Lewis S.E.; RT "Annotation of the Drosophila melanogaster euchromatic genome: a RT systematic review."; RL Genome Biol. 3:RESEARCH0083.1-RESEARCH0083.22(2002). RN [4] {ECO:0000313|EMBL:AGB93393.1, ECO:0000313|Proteomes:UP000000803} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803}; RX PubMed=12537573; RA Kaminker J.S., Bergman C.M., Kronmiller B., Carlson J., Svirskas R., RA Patel S., Frise E., Wheeler D.A., Lewis S.E., Rubin G.M., RA Ashburner M., Celniker S.E.; RT "The transposable elements of the Drosophila melanogaster euchromatin: RT a genomics perspective."; RL Genome Biol. 3:RESEARCH0084.1-RESEARCH0084.20(2002). RN [5] {ECO:0000313|EMBL:AGB93393.1, ECO:0000313|Proteomes:UP000000803} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803}; RX PubMed=12537574; RA Hoskins R.A., Smith C.D., Carlson J.W., Carvalho A.B., Halpern A., RA Kaminker J.S., Kennedy C., Mungall C.J., Sullivan B.A., Sutton G.G., RA Yasuhara J.C., Wakimoto B.T., Myers E.W., Celniker S.E., Rubin G.M., RA Karpen G.H.; RT "Heterochromatic sequences in a Drosophila whole-genome shotgun RT assembly."; RL Genome Biol. 3:RESEARCH0085-RESEARCH0085(2002). RN [6] {ECO:0000313|EMBL:AGB93393.1, ECO:0000313|Proteomes:UP000000803} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803}; RX PubMed=16110336; DOI=10.1371/journal.pcbi.0010022; RA Quesneville H., Bergman C.M., Andrieu O., Autard D., Nouaud D., RA Ashburner M., Anxolabehere D.; RT "Combined evidence annotation of transposable elements in genome RT sequences."; RL PLoS Comput. Biol. 1:166-175(2005). RN [7] {ECO:0000313|EMBL:AGB93393.1, ECO:0000313|Proteomes:UP000000803} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803}; RX PubMed=17569856; DOI=10.1126/science.1139815; RA Smith C.D., Shu S., Mungall C.J., Karpen G.H.; RT "The Release 5.1 annotation of Drosophila melanogaster RT heterochromatin."; RL Science 316:1586-1591(2007). RN [8] {ECO:0000313|EMBL:AGB93393.1, ECO:0000313|Proteomes:UP000000803} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803}; RX PubMed=17569867; DOI=10.1126/science.1139816; RA Hoskins R.A., Carlson J.W., Kennedy C., Acevedo D., Evans-Holm M., RA Frise E., Wan K.H., Park S., Mendez-Lago M., Rossi F., Villasante A., RA Dimitri P., Karpen G.H., Celniker S.E.; RT "Sequence finishing and mapping of Drosophila melanogaster RT heterochromatin."; RL Science 316:1625-1628(2007). CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AE013599; AGB93393.1; -; Genomic_DNA. DR RefSeq; NP_001260860.1; NM_001273931.1. DR UniGene; Dm.30900; -. DR SMR; A0A0B4KEH7; -. DR PaxDb; A0A0B4KEH7; -. DR EnsemblMetazoa; FBtr0336696; FBpp0307677; FBgn0033504. DR GeneID; 36084; -. DR CTD; 36084; -. DR FlyBase; FBgn0033504; CAP. DR eggNOG; ENOG410IPNR; Eukaryota. DR eggNOG; ENOG410XNVJ; LUCA. DR GeneTree; ENSGT00760000119190; -. DR OrthoDB; EOG091G002X; -. DR Reactome; R-DME-445355; Smooth Muscle Contraction. DR GenomeRNAi; 36084; -. DR Proteomes; UP000000803; Chromosome 2R. DR ExpressionAtlas; A0A0B4KEH7; differential. DR GO; GO:0007015; P:actin filament organization; IEA:InterPro. DR GO; GO:0016203; P:muscle attachment; IMP:FlyBase. DR GO; GO:0050954; P:sensory perception of mechanical stimulus; IMP:FlyBase. DR GO; GO:0007605; P:sensory perception of sound; IMP:FlyBase. DR InterPro; IPR036028; SH3-like_dom_sf. DR InterPro; IPR001452; SH3_domain. DR InterPro; IPR028506; Sorbin_SH3. DR PANTHER; PTHR45043; PTHR45043; 6. DR Pfam; PF00018; SH3_1; 2. DR Pfam; PF14604; SH3_9; 1. DR SMART; SM00326; SH3; 3. DR SUPFAM; SSF50044; SSF50044; 3. DR PROSITE; PS50002; SH3; 3. PE 4: Predicted; KW Coiled coil {ECO:0000256|SAM:Coils}; KW Complete proteome {ECO:0000313|Proteomes:UP000000803}; KW Reference proteome {ECO:0000313|Proteomes:UP000000803}; KW SH3 domain {ECO:0000256|PROSITE-ProRule:PRU00192}. FT DOMAIN 2152 2211 SH3. {ECO:0000259|PROSITE:PS50002}. FT DOMAIN 2221 2280 SH3. {ECO:0000259|PROSITE:PS50002}. FT DOMAIN 2350 2409 SH3. {ECO:0000259|PROSITE:PS50002}. FT COILED 295 329 {ECO:0000256|SAM:Coils}. FT COILED 1598 1622 {ECO:0000256|SAM:Coils}. SQ SEQUENCE 2409 AA; 271531 MW; 02B32C2FEAAE0954 CRC64; MPNNRNRNRN RNRNKRNRNQ NQNQNPSQNQ NENHQQQAEG AEDREEQQDF QTQIAVAQSS SFVDDNGNSG SVSNGPTENS EEVTNTLEKT EKKEEIFEQP ATVIQKEADS DAEMGAKNSK HRKEKSDKQA SNGKSEEQVR PPPTIIRRPP GSPRQAKVIV HRIVREEDTA NGKAQSPEPP KAVESKEQHM EVEDSKKEKP EAQQEIETKE ERENEPSPKE LPESSHLSED AQQKHVEVEE NQQVYDEVDY SKDETTDNNP QQEQHDSKEP EQYVLQLEKA MEFVENAHQQ HVAAVQSYQK QRDTEQNAQQ QEQNEAQHLQ ESTKAHQQNI AVPQILVDPK KREEGLAQQL HHDVKEEPIL NNAQQQNDDT APKSPKEVTI KVQFQTEDPY SQQPPPQKPT SKVIIHQIHV ETTDEEQNAK PTFEEVSSTT GSLAGTLSPP PRYLVESPKN VSSGQFSNFS RNVQIQEMEL NSDFSSGEFN SLQSPLVCEV DSESEGSVVL GPERSPSDQQ VPSSSRVEQH EQVRQKRAQY RNALESHFMP QLLNPRYLDS ILEENEWRNS TASSGGSDQT GIRTPKLNET FPRSQLDFSR RHKRREEAPS PLKLETKLLE ESTDLESCTR LQSALSPQSE DAELVYLSSS ASSSVSDLME LELEQAAALA ERALVDLDTD ASRLIARPDD EMSSTSTTTA DRSETEAETE TETEREGEQS RESTPVNANP TLASSQSSLL SAATPTPTPT PTPADREQLA KDTNVSGGST VSFGAASPLA ATREEFVRNM DKVRELIEMT RREQEQGELP RSPSPPPVPP PPASVPPYSP ESSSFHLASL QLKRQESNDS HCSDSTTHSQ CTAINLASPP PPPTAQPPTP PLRQKPAPPP VPQPVSPPAP PTPQSEPELS VADSVANANA DVDADADTDT EAIKKLRLLC TEQLASMPYG EQVLEELASV AQNISDQSQN KMPYPMPQLP HIKELQLNAN ESKSSSAWLG LPTQSDPKLL VCLSPGQRDL VNNQTQPDDL LDAHQKFVER RGYHELSKAQ VLEQDHQQQQ SEMLKTAAMM RELRKSLSPP APPVPPPPVP VKSAETAAKA TAHENAKRDD ASEQKQKIAA CESSSLENKP RRAADLGAQQ SAEQRQSSST TTSSHKATTE TMSSDTAKFP TLDSMESELA RMFPQHKGDI FEEQRKRFSN IEFPSHQPVS QTKRYSNIET SSYESKKRME NGQVVYDVST SSHEKKEQGD PPKDQPVPPV PPPPIMSATK LNGNTFIDGD VAPKNSQPSR ESGSGSGNGT YEEFRQRAKA AADAFGEQRE QQNGLDQDRV FKDFDRLSQQ MHAELQSTRE KREKSASMYD LSGFTRPASG HPRLDELQQR RHAHMQELER EIERSAKSRQ ERMSSVPRQM EATPPRTHEI PIELEPRSRR AESLCNLNEP PPRPHTTVGH YNHPVVQDDW SRYANDLGYS ENIARPFARE VEICYQRQNQ RTPHCIRAPR LSASTNDLSS SSQYSYDTFN AYGGRRTHAP MLNQAQQQQR PHYGSCYSMI ERDPNPRYIS TTSRRGVSPA PPPVATPQQQ QVPPPAYDRQ QRRSSLPREL HEQQLKYILS KEEELKFEVE RLQQERRRLM EEMQRAPVLP APQRRESYRP AAKLPTLSED EVFRQQMAEE WMNKVAEREE RRQHKIIRIS KIEDEHDHSA VDKATISDEF LDRVKERRHK LSMPADSDWE SGAESQPQPA AQSQPESDVE APPVRILEGQ AEANLRQLPR HLREFAKFST SEQLPDGAQM ERHEEQERRE EATDNAHSSA TKKTSIVKTY KVSRLPPSVQ AFERSSSNSE LQRPFVRRQL SDASRPAYRP NEVTRPSYKS NGYVSEPEPN YDSDYSTVRY RTQNPHRVQS VSSAVNVRNL NQDEKLYGTM PNPIKSAQNS YKNQPGRIEN YTTGHSSVSE KEKKEWWDEV MDIFNGNLEQ SKLSPLYTEG NLSRALAKES GYTSDSNLVF RKKEVPVSSP LSPVEQKQAY KSLQAGGEPP LLGFRKPAPE KPRDLDPNAP PIPPQPPVKG LSSYDFPYST DTVDGSDVNI HFKTPIRHEQ RQNLSEEELA IRQAEHMQKL YHEERRRKYL QELQDMNSRR HTDNFTPSQK SPIALNRYDD FPTDVTLKSL VGPKTVARAL FNFQGQTSKE LSFRKGDTIY IRRQIDANWY EGEHNAMIGL LPASYVEIVS RDGARTPSKR PSEGQARAKY NFQAQSGIEL SLNKGELVTL TRRVDGNWFE GKIANRKGIF PCSYVEVLTD IGAEDIAART TTVITSQSTT NLRPNLDVLR TNINNEFNTL TQNGAQPPNG ILKETRTLHK TDALHVDTSS EPLAYRALYK YRPQNSDELE LLEGDVVHVL EKCDDGWFVG TSQRTGCFGT FPGNYVERA //