ID A0A0B4HRR4_METMF Unreviewed; 303 AA. AC A0A0B4HRR4; DT 04-MAR-2015, integrated into UniProtKB/TrEMBL. DT 04-MAR-2015, sequence version 1. DT 29-MAY-2024, entry version 30. DE SubName: Full=Protein kinase domain containing protein {ECO:0000313|EMBL:KID97968.1}; DE Flags: Fragment; GN ORFNames=MAJ_06045 {ECO:0000313|EMBL:KID97968.1}; OS Metarhizium majus (strain ARSEF 297). OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes; OC Hypocreomycetidae; Hypocreales; Clavicipitaceae; Metarhizium; OC Metarhizium majus. OX NCBI_TaxID=1276143 {ECO:0000313|EMBL:KID97968.1, ECO:0000313|Proteomes:UP000031176}; RN [1] {ECO:0000313|EMBL:KID97968.1, ECO:0000313|Proteomes:UP000031176} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=ARSEF 297 {ECO:0000313|EMBL:KID97968.1, RC ECO:0000313|Proteomes:UP000031176}; RX PubMed=25368161; DOI=10.1073/pnas.1412662111; RA Hu X., Xiao G., Zheng P., Shang Y., Su Y., Zhang X., Liu X., Zhan S., RA St Leger R.J., Wang C.; RT "Trajectory and genomic determinants of fungal-pathogen speciation and host RT adaptation."; RL Proc. Natl. Acad. Sci. U.S.A. 111:16796-16801(2014). CC -!- SIMILARITY: Belongs to the protein kinase superfamily. CC {ECO:0000256|RuleBase:RU000304}. CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ CC whole genome shotgun (WGS) entry which is preliminary data. CC {ECO:0000313|EMBL:KID97968.1}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AZNE01000028; KID97968.1; -; Genomic_DNA. DR RefSeq; XP_014576962.1; XM_014721476.1. DR AlphaFoldDB; A0A0B4HRR4; -. DR HOGENOM; CLU_073118_0_0_1; -. DR OrthoDB; 775113at2759; -. DR Proteomes; UP000031176; Unassembled WGS sequence. DR GO; GO:0005737; C:cytoplasm; IEA:TreeGrafter. DR GO; GO:0005634; C:nucleus; IEA:TreeGrafter. DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule. DR GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. DR GO; GO:0051598; P:meiotic recombination checkpoint signaling; IEA:TreeGrafter. DR GO; GO:0044773; P:mitotic DNA damage checkpoint signaling; IEA:TreeGrafter. DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW. DR CDD; cd00180; PKc; 1. DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1. DR InterPro; IPR011009; Kinase-like_dom_sf. DR InterPro; IPR000719; Prot_kinase_dom. DR InterPro; IPR017441; Protein_kinase_ATP_BS. DR InterPro; IPR008271; Ser/Thr_kinase_AS. DR PANTHER; PTHR44167; OVARIAN-SPECIFIC SERINE/THREONINE-PROTEIN KINASE LOK-RELATED; 1. DR PANTHER; PTHR44167:SF8; OVARIAN-SPECIFIC SERINE_THREONINE-PROTEIN KINASE LOK; 1. DR Pfam; PF00069; Pkinase; 1. DR SMART; SM00220; S_TKc; 1. DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1. DR PROSITE; PS00107; PROTEIN_KINASE_ATP; 1. DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1. DR PROSITE; PS00108; PROTEIN_KINASE_ST; 1. PE 3: Inferred from homology; KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE- KW ProRule:PRU10141}; Kinase {ECO:0000313|EMBL:KID97968.1}; KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE- KW ProRule:PRU10141}; Reference proteome {ECO:0000313|Proteomes:UP000031176}; KW Serine/threonine-protein kinase {ECO:0000256|RuleBase:RU000304}; KW Transferase {ECO:0000313|EMBL:KID97968.1}. FT DOMAIN 29..280 FT /note="Protein kinase" FT /evidence="ECO:0000259|PROSITE:PS50011" FT BINDING 58 FT /ligand="ATP" FT /ligand_id="ChEBI:CHEBI:30616" FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10141" FT NON_TER 1 FT /evidence="ECO:0000313|EMBL:KID97968.1" SQ SEQUENCE 303 AA; 33455 MW; 2133D3179C87D20B CRC64; MNTSEAAAWS DDDAERAKIE NRGLSTTKYV RGSRLGLGGS SIVYKTLRVS DGKVLAGKSS KAPKGLKREA GILRLLQHEH IVAFVELYHD PVCPVSGLLL MELCPHGTLQ RRIDQATPHM ARGEVLSVVR QIARALAYMH ARGMYHSDVK PRNVLIRDFD PVHVVLADCA DVRMLGQPGQ LKGTPAYWSP EMKARRAHCG PADDMWALGV TLLGMVGQWP QMVYTVMDLE VYPKRCFEHA CRLGELNPGV GIVSLLTGLL AWEAEERMTA EECVLVVEEL GAAEGGEELG IRSPEAFRPM LFW //