ID A0A0A7LEJ5_9MAGN Unreviewed; 500 AA. AC A0A0A7LEJ5; DT 04-MAR-2015, integrated into UniProtKB/TrEMBL. DT 04-MAR-2015, sequence version 1. DT 22-FEB-2023, entry version 29. DE RecName: Full=NAD(P)H-quinone oxidoreductase chain 4, chloroplastic {ECO:0000256|ARBA:ARBA00016792, ECO:0000256|HAMAP-Rule:MF_00491}; DE EC=7.1.1.- {ECO:0000256|HAMAP-Rule:MF_00491}; DE AltName: Full=NAD(P)H dehydrogenase, chain 4 {ECO:0000256|ARBA:ARBA00032800, ECO:0000256|HAMAP-Rule:MF_00491}; DE AltName: Full=NADH-plastoquinone oxidoreductase chain 4 {ECO:0000256|ARBA:ARBA00030440, ECO:0000256|HAMAP-Rule:MF_00491}; GN Name=ndhD {ECO:0000256|HAMAP-Rule:MF_00491, GN ECO:0000313|EMBL:AIZ57599.1}; GN ORFNames=CfcCp073 {ECO:0000313|EMBL:AIZ57599.1}; OS Clematis fusca var. coreana. OG Plastid; Chloroplast {ECO:0000313|EMBL:AIZ57599.1}. OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; OC Spermatophyta; Magnoliopsida; Ranunculales; Ranunculaceae; Ranunculoideae; OC Anemoneae; Clematis. OX NCBI_TaxID=1582009 {ECO:0000313|EMBL:AIZ57599.1}; RN [1] {ECO:0000313|EMBL:AIZ57599.1} RP NUCLEOTIDE SEQUENCE. RA Park K.T., Park S.; RT "Complete chloroplast genome sequence of Clematis fusca var. coreana RT (Ranunculaceae)."; RL Submitted (SEP-2014) to the EMBL/GenBank/DDBJ databases. CC -!- CATALYTIC ACTIVITY: CC Reaction=a plastoquinone + (n+1) H(+)(in) + NADH = a plastoquinol + n CC H(+)(out) + NAD(+); Xref=Rhea:RHEA:42608, Rhea:RHEA-COMP:9561, CC Rhea:RHEA-COMP:9562, ChEBI:CHEBI:15378, ChEBI:CHEBI:17757, CC ChEBI:CHEBI:57540, ChEBI:CHEBI:57945, ChEBI:CHEBI:62192; CC Evidence={ECO:0000256|HAMAP-Rule:MF_00491}; CC -!- CATALYTIC ACTIVITY: CC Reaction=a plastoquinone + (n+1) H(+)(in) + NADPH = a plastoquinol + n CC H(+)(out) + NADP(+); Xref=Rhea:RHEA:42612, Rhea:RHEA-COMP:9561, CC Rhea:RHEA-COMP:9562, ChEBI:CHEBI:15378, ChEBI:CHEBI:17757, CC ChEBI:CHEBI:57783, ChEBI:CHEBI:58349, ChEBI:CHEBI:62192; CC Evidence={ECO:0000256|HAMAP-Rule:MF_00491}; CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi- CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}. Plastid, CC chloroplast thylakoid membrane {ECO:0000256|HAMAP-Rule:MF_00491}; CC Multi-pass membrane protein {ECO:0000256|HAMAP-Rule:MF_00491}. CC -!- SIMILARITY: Belongs to the complex I subunit 4 family. CC {ECO:0000256|ARBA:ARBA00009025, ECO:0000256|HAMAP-Rule:MF_00491}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; KM652489; AIZ57599.1; -; Genomic_DNA. DR AlphaFoldDB; A0A0A7LEJ5; -. DR GO; GO:0009535; C:chloroplast thylakoid membrane; IEA:UniProtKB-SubCell. DR GO; GO:0008137; F:NADH dehydrogenase (ubiquinone) activity; IEA:InterPro. DR GO; GO:0048038; F:quinone binding; IEA:UniProtKB-KW. DR GO; GO:0042773; P:ATP synthesis coupled electron transport; IEA:InterPro. DR HAMAP; MF_00491; NDH1_NuoM; 1. DR InterPro; IPR022997; NADH_Q_OxRdtase_chain4. DR InterPro; IPR010227; NADH_Q_OxRdtase_chainM/4. DR InterPro; IPR003918; NADH_UbQ_OxRdtase. DR InterPro; IPR001750; ND/Mrp_mem. DR PANTHER; PTHR43507; NADH-UBIQUINONE OXIDOREDUCTASE CHAIN 4; 1. DR PANTHER; PTHR43507:SF1; NADH-UBIQUINONE OXIDOREDUCTASE CHAIN 4; 1. DR Pfam; PF00361; Proton_antipo_M; 1. DR PRINTS; PR01437; NUOXDRDTASE4. DR TIGRFAMs; TIGR01972; NDH_I_M; 1. PE 3: Inferred from homology; KW Chloroplast {ECO:0000313|EMBL:AIZ57599.1}; KW Membrane {ECO:0000256|HAMAP-Rule:MF_00491}; KW NAD {ECO:0000256|ARBA:ARBA00023027, ECO:0000256|HAMAP-Rule:MF_00491}; KW NADP {ECO:0000256|HAMAP-Rule:MF_00491}; KW Plastid {ECO:0000313|EMBL:AIZ57599.1}; KW Plastoquinone {ECO:0000256|HAMAP-Rule:MF_00491}; KW Quinone {ECO:0000256|HAMAP-Rule:MF_00491}; KW Thylakoid {ECO:0000256|HAMAP-Rule:MF_00491}; KW Translocase {ECO:0000256|ARBA:ARBA00022967, ECO:0000256|HAMAP- KW Rule:MF_00491}; Transmembrane {ECO:0000256|HAMAP-Rule:MF_00491}; KW Transmembrane helix {ECO:0000256|HAMAP-Rule:MF_00491}. FT TRANSMEM 6..25 FT /note="Helical" FT /evidence="ECO:0000256|HAMAP-Rule:MF_00491" FT TRANSMEM 32..56 FT /note="Helical" FT /evidence="ECO:0000256|HAMAP-Rule:MF_00491" FT TRANSMEM 76..101 FT /note="Helical" FT /evidence="ECO:0000256|HAMAP-Rule:MF_00491" FT TRANSMEM 113..129 FT /note="Helical" FT /evidence="ECO:0000256|HAMAP-Rule:MF_00491" FT TRANSMEM 135..155 FT /note="Helical" FT /evidence="ECO:0000256|HAMAP-Rule:MF_00491" FT TRANSMEM 167..191 FT /note="Helical" FT /evidence="ECO:0000256|HAMAP-Rule:MF_00491" FT TRANSMEM 211..234 FT /note="Helical" FT /evidence="ECO:0000256|HAMAP-Rule:MF_00491" FT TRANSMEM 246..264 FT /note="Helical" FT /evidence="ECO:0000256|HAMAP-Rule:MF_00491" FT TRANSMEM 276..293 FT /note="Helical" FT /evidence="ECO:0000256|HAMAP-Rule:MF_00491" FT TRANSMEM 305..323 FT /note="Helical" FT /evidence="ECO:0000256|HAMAP-Rule:MF_00491" FT TRANSMEM 335..353 FT /note="Helical" FT /evidence="ECO:0000256|HAMAP-Rule:MF_00491" FT TRANSMEM 374..404 FT /note="Helical" FT /evidence="ECO:0000256|HAMAP-Rule:MF_00491" FT TRANSMEM 416..441 FT /note="Helical" FT /evidence="ECO:0000256|HAMAP-Rule:MF_00491" FT TRANSMEM 462..479 FT /note="Helical" FT /evidence="ECO:0000256|HAMAP-Rule:MF_00491" FT DOMAIN 131..413 FT /note="NADH:quinone oxidoreductase/Mrp antiporter membrane FT subunit" FT /evidence="ECO:0000259|Pfam:PF00361" SQ SEQUENCE 500 AA; 56537 MW; 51AF17D34262E536 CRC64; MNDFPWLTII VVLPIFAGTF IFFFPHRGNK VIRWYTICIC LLELLLMAYV FCYHFQLDDP LIQLEQDYKW INFFDFHWRL GIDGLSIGPI LLTGFITTLA TLAAWPVTRD SKLFHFLMLA MYSGQIGLFS SRDLLLFFIM WELELIPVYL LLSMWGGKKR LYSATKFILY TAGGSIFLLM GVLGMGLYGF NEPTLNFETS ANQPYPVALE ILFYFGFLIA YAIKLPIIPL HTWLPDTHGE AHYSTCMLLA GILLKMGAYG LVRINMELLP HAHSIFSPWL MIVGAIQIIY AASASPGQRN LKKRIAYSSV SHMGFIIIGI SSITDTGLNG ALLQMISHGF IGAALFFLAG TSYDRTRLVY LDEMGGITIP MPKIFTMFSS FSLASLALPG MSGFVAEFVV FFGLIMSQKF LLMPKILITF VTAIGMILTP IYSLSMLRQM FYGYKQFNSQ NSHFLDSGPR ELFLSICIFL PVIGIGIYPD FVLSLSIDKV ETIISNYFYR //