ID A0A0A7KT43_9TELE Unreviewed; 285 AA. AC A0A0A7KT43; DT 04-MAR-2015, integrated into UniProtKB/TrEMBL. DT 04-MAR-2015, sequence version 1. DT 27-NOV-2024, entry version 37. DE SubName: Full=Homeodomain protein HoxA2b {ECO:0000313|EMBL:AIZ49441.1}; DE Flags: Fragment; GN Name=HoxA2b {ECO:0000313|EMBL:AIZ49441.1}; OS Ptychobarbus dipogon. OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; OC Cyprinidae; Schizopygopsinae; Ptychobarbus. OX NCBI_TaxID=263530 {ECO:0000313|EMBL:AIZ49441.1}; RN [1] {ECO:0000313|EMBL:AIZ49441.1} RP NUCLEOTIDE SEQUENCE. RC STRAIN=A2b2563_17 {ECO:0000313|EMBL:AIZ49441.1}; RX PubMed=25470283; RA Ma W., Zhu Z.H., Bi X.Y., Murphy R.W., Wang S.Y., Gao Y., Xiao H., RA Zhang Y.P., Luo J.; RT "Allopolyploidization is not so simple: evidence from the origin of the RT tribe Cyprinini (Teleostei: Cypriniformes)."; RL Curr. Mol. Med. 14:1331-1338(2014). CC -!- FUNCTION: Sequence-specific transcription factor which is part of a CC developmental regulatory system that provides cells with specific CC positional identities on the anterior-posterior axis. CC {ECO:0000256|ARBA:ARBA00003263}. CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123, CC ECO:0000256|PROSITE-ProRule:PRU00108, ECO:0000256|RuleBase:RU000682}. CC -!- SIMILARITY: Belongs to the Antp homeobox family. Proboscipedia CC subfamily. {ECO:0000256|ARBA:ARBA00038135}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; KJ474696; AIZ49441.1; -; Genomic_DNA. DR AlphaFoldDB; A0A0A7KT43; -. DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IEA:InterPro. DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IEA:TreeGrafter. DR CDD; cd00086; homeodomain; 1. DR FunFam; 1.10.10.60:FF:000145; homeobox protein Hox-A2; 1. DR Gene3D; 1.10.10.60; Homeodomain-like; 1. DR InterPro; IPR001356; HD. DR InterPro; IPR020479; HD_metazoa. DR InterPro; IPR001827; Homeobox_Antennapedia_CS. DR InterPro; IPR017970; Homeobox_CS. DR InterPro; IPR009057; Homeodomain-like_sf. DR PANTHER; PTHR45664:SF3; HOMEOBOX PROTEIN HOX-A2; 1. DR PANTHER; PTHR45664; PROTEIN ZERKNUELLT 1-RELATED; 1. DR Pfam; PF00046; Homeodomain; 1. DR PRINTS; PR00024; HOMEOBOX. DR SMART; SM00389; HOX; 1. DR SUPFAM; SSF46689; Homeodomain-like; 1. DR PROSITE; PS00032; ANTENNAPEDIA; 1. DR PROSITE; PS00027; HOMEOBOX_1; 1. DR PROSITE; PS50071; HOMEOBOX_2; 1. PE 3: Inferred from homology; KW Developmental protein {ECO:0000256|ARBA:ARBA00022473}; KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE- KW ProRule:PRU00108}; KW Homeobox {ECO:0000256|ARBA:ARBA00023155, ECO:0000256|PROSITE- KW ProRule:PRU00108}; KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE- KW ProRule:PRU00108}; Transcription {ECO:0000256|ARBA:ARBA00023163}; KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}. FT DOMAIN 108..168 FT /note="Homeobox" FT /evidence="ECO:0000259|PROSITE:PS50071" FT DNA_BIND 110..169 FT /note="Homeobox" FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00108" FT REGION 1..109 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT REGION 163..195 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COMPBIAS 8..55 FT /note="Polar residues" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COMPBIAS 77..104 FT /note="Polar residues" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COMPBIAS 171..187 FT /note="Basic and acidic residues" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT NON_TER 1 FT /evidence="ECO:0000313|EMBL:AIZ49441.1" FT NON_TER 285 FT /evidence="ECO:0000313|EMBL:AIZ49441.1" SQ SEQUENCE 285 AA; 31055 MW; BE0BD8E39D96C158 CRC64; FPPVGDAFQS SSIKSSTLSH STLIPPPFEQ TIPSLNPGSH PRHSRPKQNP NGSCPLPAAS LPPEYPWMKE KKASKKSQTT STATTTTNPG PLYFSPQGSP EISDGGNGAT RRLRTAYTNT QLLELEKEFH FNKYLCRPRR VEIAALLDLT ERQVKVWFQN RRMKHKRQTQ CKENHHGDGK APSLEEAGGR GDGKSFFEQV ANNVSGALLE REGYPLQQNT LTSQQSQNGH NGDSQSATVS LLGSNDKHLK HFPNPSLTVP ICASTMAPDC ASAQNNGSPS ALDVS //