ID A0A0A7HGG1_9CAUD Unreviewed; 904 AA. AC A0A0A7HGG1; DT 04-MAR-2015, integrated into UniProtKB/TrEMBL. DT 04-MAR-2015, sequence version 1. DT 15-MAR-2017, entry version 11. DE RecName: Full=DNA polymerase {ECO:0000256|RuleBase:RU000442}; DE EC=2.7.7.7 {ECO:0000256|RuleBase:RU000442}; GN ORFNames=VR25_050 {ECO:0000313|EMBL:AIZ02394.1}; OS Escherichia phage vB_EcoM_VR25. OC Viruses; dsDNA viruses, no RNA stage; Caudovirales; Myoviridae; OC Tevenvirinae; Sp18virus. OX NCBI_TaxID=1567028 {ECO:0000313|EMBL:AIZ02394.1, ECO:0000313|Proteomes:UP000030717}; RN [1] {ECO:0000313|EMBL:AIZ02394.1, ECO:0000313|Proteomes:UP000030717} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RA Kaliniene L., Meskys R., Simoliunas E., Zajanckauskaite A., RA Truncaite L.; RT "VR bacteriophages - a small but diverse group of low-temperature RT viruses."; RL Submitted (OCT-2014) to the EMBL/GenBank/DDBJ databases. CC -!- CATALYTIC ACTIVITY: Deoxynucleoside triphosphate + DNA(n) = CC diphosphate + DNA(n+1). {ECO:0000256|RuleBase:RU000442}. CC -!- SIMILARITY: Belongs to the DNA polymerase type-B family. CC {ECO:0000256|RuleBase:RU000442}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; KP007361; AIZ02394.1; -; Genomic_DNA. DR RefSeq; YP_009209792.1; NC_028925.1. DR GeneID; 26636212; -. DR KEGG; vg:26636212; -. DR KO; K02319; -. DR OrthoDB; VOG0900001M; -. DR Proteomes; UP000030717; Genome. DR GO; GO:0008408; F:3'-5' exonuclease activity; IEA:InterPro. DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW. DR GO; GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-KW. DR GO; GO:0000166; F:nucleotide binding; IEA:InterPro. DR GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW. DR Gene3D; 3.30.420.10; -; 1. DR Gene3D; 3.90.1600.10; -; 2. DR InterPro; IPR006172; DNA-dir_DNA_pol_B. DR InterPro; IPR017964; DNA-dir_DNA_pol_B_CS. DR InterPro; IPR006133; DNA-dir_DNA_pol_B_exonuc. DR InterPro; IPR006134; DNA-dir_DNA_pol_B_multi_dom. DR InterPro; IPR023211; DNA_pol_palm_dom. DR InterPro; IPR012337; RNaseH-like_dom. DR Pfam; PF00136; DNA_pol_B; 1. DR Pfam; PF03104; DNA_pol_B_exo1; 1. DR PRINTS; PR00106; DNAPOLB. DR SMART; SM00486; POLBc; 1. DR SUPFAM; SSF53098; SSF53098; 1. DR PROSITE; PS00116; DNA_POLYMERASE_B; 1. PE 3: Inferred from homology; KW Complete proteome {ECO:0000313|Proteomes:UP000030717}; KW DNA replication {ECO:0000256|RuleBase:RU000442}; KW DNA-binding {ECO:0000256|RuleBase:RU000442}; KW DNA-directed DNA polymerase {ECO:0000256|RuleBase:RU000442}; KW Nucleotidyltransferase {ECO:0000256|RuleBase:RU000442}; KW Transferase {ECO:0000256|RuleBase:RU000442}. FT DOMAIN 96 294 DNA_pol_B_exo1. {ECO:0000259|Pfam: FT PF03104}. FT DOMAIN 369 770 DNA_pol_B. {ECO:0000259|Pfam:PF00136}. SQ SEQUENCE 904 AA; 103716 MW; 1231F65A374D4AC9 CRC64; MQEFYLTIEQ IGDNLHERYI DKNGNERTRE IPYTPCLFMH AREGQATKYS DIYNKGCVKK EFDSMRDASQ WMKRMNDMGL EAMGMDDFKL AYLSDRYPHE IKYDSSKIRV ANFDIEVTSP DGFPEPSEAR HPIDALTHYD SVDDKFYVFD LLGSPYATVE QWSIDIAAKL QEDGGDEVPS EILEKIVYMA FDSEEEMLQQ YLVFWNEKTP VMLTGWNIEK FDIPYIYNRL KNVFGEATAK RLSPHRRTKV KVINNGFGEE QEIIQILGVS VLDYLDLYKK FSFTNQPSYS LDYVAESELG VGKLPYDGPI SKLRESNHQR YISYNIIDVY RVVQIDRKRQ FINLSQSMGY YAKMQIQSVF SPIKTWDAII FNSLKTQNKV IPETKSHVRQ SFPGAFVKEP IPNAYKYVMS CDLTSLYPSI IRQINISPET IAGSFAPAHM HEYIAGTADR PSDAFSCAPN GMMYFKDVAG IIPTEVTKVF NQRKEHKGYM LAAQRNGELI KEALSNPGTG TTEPEVDYRH DFDDNMKTTL HGLNQTVLNG MLYKAQMEEV AGMTAQINRK LLINSCYGAL GNIWFRYFDL RNATAITSFG QLALQWIERK VNEYFDGVCG TQGQTYVFYG DTDSIYIQCD NLIKKVGGES KFRDTNHLVD FMDKFAKDRL EPAIDKAFRE LAEYMNNKQH LMFMDREAIA CPPLGSKGVG GFWTAKKRYA LNVYDMEGTR YAVPKLKIMG LETQKSSTPK ACQKALKECI RRMLQEGEES LQTYFKEFNK EFNELNYMTI AGVSSVNNIQ KYNEGGFPGF KCPAHIKGVL AYMRATKGLK TVPQIMEGEK VYVLPLKVGN PFGETVIAWP SGIELPIEIR DQVLQWMDYN TLFQKTFVKP LTGFSEAAKV DYEKKATLFD MFDF //