ID A0A0A7DW40_LYCBA Unreviewed; 712 AA. AC A0A0A7DW40; DT 04-MAR-2015, integrated into UniProtKB/TrEMBL. DT 04-MAR-2015, sequence version 1. DT 07-OCT-2020, entry version 16. DE RecName: Full=1-deoxy-D-xylulose-5-phosphate synthase {ECO:0000256|ARBA:ARBA00013150}; DE EC=2.2.1.7 {ECO:0000256|ARBA:ARBA00013150}; GN Name=DXS2 {ECO:0000313|EMBL:AIX87492.1}; OS Lycium barbarum (Barbary matrimony-vine). OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; OC asterids; lamiids; Solanales; Solanaceae; Solanoideae; Lycieae; Lycium. OX NCBI_TaxID=112863 {ECO:0000313|EMBL:AIX87492.1}; RN [1] {ECO:0000313|EMBL:AIX87492.1} RP NUCLEOTIDE SEQUENCE. RX PubMed=25511605; RA Liu Y., Zeng S., Sun W., Wu M., Hu W., Shen X., Wang Y.; RT "Comparative analysis of carotenoid accumulation in two goji ( Lycium RT barbarum L. and L. ruthenicum Murr.) fruits."; RL BMC Plant Biol. 14:269-269(2014). CC -!- CATALYTIC ACTIVITY: CC Reaction=D-glyceraldehyde 3-phosphate + H(+) + pyruvate = 1-deoxy-D- CC xylulose 5-phosphate + CO2; Xref=Rhea:RHEA:12605, ChEBI:CHEBI:15361, CC ChEBI:CHEBI:15378, ChEBI:CHEBI:16526, ChEBI:CHEBI:57792, CC ChEBI:CHEBI:59776; EC=2.2.1.7; CC Evidence={ECO:0000256|ARBA:ARBA00000647}; CC -!- COFACTOR: CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420; CC Evidence={ECO:0000256|ARBA:ARBA00001946}; CC -!- PATHWAY: Metabolic intermediate biosynthesis; 1-deoxy-D-xylulose 5- CC phosphate biosynthesis; 1-deoxy-D-xylulose 5-phosphate from D- CC glyceraldehyde 3-phosphate and pyruvate: step 1/1. CC {ECO:0000256|ARBA:ARBA00004980}. CC -!- SUBUNIT: Homodimer. {ECO:0000256|ARBA:ARBA00011738}. CC -!- SIMILARITY: Belongs to the transketolase family. DXPS subfamily. CC {ECO:0000256|ARBA:ARBA00011081}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; KF957679; AIX87492.1; -; mRNA. DR UniPathway; UPA00064; UER00091. DR GO; GO:0008661; F:1-deoxy-D-xylulose-5-phosphate synthase activity; IEA:UniProtKB-EC. DR GO; GO:0052865; P:1-deoxy-D-xylulose 5-phosphate biosynthetic process; IEA:UniProtKB-UniPathway. DR GO; GO:0016114; P:terpenoid biosynthetic process; IEA:InterPro. DR GO; GO:0009228; P:thiamine biosynthetic process; IEA:UniProtKB-KW. DR CDD; cd02007; TPP_DXS; 1. DR Gene3D; 3.40.50.920; -; 1. DR HAMAP; MF_00315; DXP_synth; 1. DR InterPro; IPR005477; Dxylulose-5-P_synthase. DR InterPro; IPR029061; THDP-binding. DR InterPro; IPR009014; Transketo_C/PFOR_II. DR InterPro; IPR005475; Transketolase-like_Pyr-bd. DR InterPro; IPR033248; Transketolase_C. DR PANTHER; PTHR43322; PTHR43322; 1. DR Pfam; PF13292; DXP_synthase_N; 1. DR Pfam; PF02779; Transket_pyr; 1. DR Pfam; PF02780; Transketolase_C; 1. DR SMART; SM00861; Transket_pyr; 1. DR SUPFAM; SSF52518; SSF52518; 2. DR SUPFAM; SSF52922; SSF52922; 1. DR TIGRFAMs; TIGR00204; dxs; 1. PE 2: Evidence at transcript level; KW Isoprene biosynthesis {ECO:0000256|ARBA:ARBA00023229}; KW Magnesium {ECO:0000256|ARBA:ARBA00022842}; KW Metal-binding {ECO:0000256|ARBA:ARBA00022723}; KW Thiamine biosynthesis {ECO:0000256|ARBA:ARBA00022977}; KW Thiamine pyrophosphate {ECO:0000256|ARBA:ARBA00023052}; KW Transferase {ECO:0000256|ARBA:ARBA00022679}. FT DOMAIN 392..557 FT /note="Transket_pyr" FT /evidence="ECO:0000259|SMART:SM00861" SQ SEQUENCE 712 AA; 76844 MW; 7B80D9EDE90E39F0 CRC64; MAVSSGPVFR INQPTLPYLT SPRFHLTKKK FLVKASVNGS DEINGKIVRN KEKDSWQIDF SGDKPPTPFL DTINYPMHMK NLSKLDLEHL AAELRAEIVY SVAKTGGHLS SSLGVVDLTV ALHHVFDTPE DKIIWDVGHQ AYAHKILTGR RSKMHTIRKT SGLAPFPKRD ESVYDAFGAG HSSTSISAGL GMAVARDLLG KNNHVISIIG DGSMTAGQAY EALNNAGFLD SNLIVILNDN EQVSLPTATL DGPATPVGAL SGALSKLQAS RKFRQLREAA KSITKQIGPQ AHEVAAKVDE YARGMISASG STLFEELGLY YIGPVDGHNI EDLISILQKV KSMPAPGPVL IHIVTEKGKG YPPAEAAADK MHGVAQFDPK TGQQFKAKSP TLSYTQYFAE SLIKEAENDD KIVAIHAAMG GGTGLNYFQK RFPERCFDVG IAEQHAVTFA AGLATEGLKP FCAIYSSFLQ RGYDQVVHDV DLQKLPVRFA MDRAGLVGAD GPTHCGAFDV AYMTCLPNMV VMAPSDEAEL MHMVATAAAI HDRPSCFRFP RGNGIGAVLP QNNKGIPIEV GKGRILREGE RVAILGYGSI VQQCLGAADI SQSHNVRITV ADARFCKPLD ADLIRRLAKE HEILITVEEG SIGGFGSHVA HFLSLNSILD GPLKLRSMVL PDRYIDHGSP LDQIEAAGLS SRHISATILT LLGRPKEAMV VN //