ID A0A0A6YWR5_MOUSE Unreviewed; 223 AA. AC A0A0A6YWR5; DT 04-FEB-2015, integrated into UniProtKB/TrEMBL. DT 05-OCT-2016, sequence version 5. DT 30-AUG-2017, entry version 25. DE SubName: Full=LIM/homeobox protein Lhx4 {ECO:0000313|Ensembl:ENSMUSP00000141662}; DE Flags: Fragment; GN Name=Lhx4 {ECO:0000313|Ensembl:ENSMUSP00000141662, GN ECO:0000313|MGI:MGI:101776}; OS Mus musculus (Mouse). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; OC Muroidea; Muridae; Murinae; Mus; Mus. OX NCBI_TaxID=10090 {ECO:0000313|Ensembl:ENSMUSP00000141662, ECO:0000313|Proteomes:UP000000589}; RN [1] {ECO:0000313|Ensembl:ENSMUSP00000141662, ECO:0000313|Proteomes:UP000000589} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000141662, RC ECO:0000313|Proteomes:UP000000589}; RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112; RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., RA She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., RA Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., RA Zhou S., Teague B., Potamousis K., Churas C., Place M., Herschleb J., RA Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., RA Lindblad-Toh K., Eichler E.E., Ponting C.P.; RT "Lineage-specific biology revealed by a finished genome assembly of RT the mouse."; RL PLoS Biol. 7:E1000112-E1000112(2009). RN [2] {ECO:0000313|Ensembl:ENSMUSP00000141662} RP IDENTIFICATION. RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000141662}; RG Ensembl; RL Submitted (DEC-2014) to UniProtKB. CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|PROSITE- CC ProRule:PRU00108, ECO:0000256|RuleBase:RU000682, CC ECO:0000256|SAAS:SAAS00113198}. CC -!- CAUTION: The sequence shown here is derived from an Ensembl CC automatic analysis pipeline and should be considered as CC preliminary data. {ECO:0000313|Ensembl:ENSMUSP00000141662}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AC117598; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; AC121314; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR SMR; A0A0A6YWR5; -. DR PaxDb; A0A0A6YWR5; -. DR Ensembl; ENSMUST00000195275; ENSMUSP00000141662; ENSMUSG00000026468. DR MGI; MGI:101776; Lhx4. DR eggNOG; KOG4577; Eukaryota. DR eggNOG; ENOG410XPDC; LUCA. DR GeneTree; ENSGT00760000118921; -. DR Proteomes; UP000000589; Chromosome 1. DR Bgee; ENSMUSG00000026468; -. DR ExpressionAtlas; A0A0A6YWR5; baseline and differential. DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro. DR GO; GO:0009887; P:animal organ morphogenesis; IEA:Ensembl. DR GO; GO:0021526; P:medial motor column neuron differentiation; IEA:Ensembl. DR GO; GO:0008045; P:motor neuron axon guidance; IEA:Ensembl. DR GO; GO:0043066; P:negative regulation of apoptotic process; IEA:Ensembl. DR GO; GO:0001890; P:placenta development; IEA:Ensembl. DR GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro. DR InterPro; IPR009057; Homeobox-like. DR InterPro; IPR017970; Homeobox_CS. DR InterPro; IPR001356; Homeobox_dom. DR InterPro; IPR001781; Znf_LIM. DR Pfam; PF00046; Homeobox; 1. DR Pfam; PF00412; LIM; 1. DR SMART; SM00389; HOX; 1. DR SMART; SM00132; LIM; 1. DR SUPFAM; SSF46689; SSF46689; 1. DR PROSITE; PS00027; HOMEOBOX_1; 1. DR PROSITE; PS50071; HOMEOBOX_2; 1. DR PROSITE; PS00478; LIM_DOMAIN_1; 1. DR PROSITE; PS50023; LIM_DOMAIN_2; 1. PE 4: Predicted; KW Complete proteome {ECO:0000313|Proteomes:UP000000589}; KW DNA-binding {ECO:0000256|PROSITE-ProRule:PRU00108, KW ECO:0000256|RuleBase:RU000682, ECO:0000256|SAAS:SAAS00474877}; KW Homeobox {ECO:0000256|PROSITE-ProRule:PRU00108, KW ECO:0000256|RuleBase:RU000682, ECO:0000256|SAAS:SAAS00474775}; KW LIM domain {ECO:0000256|PROSITE-ProRule:PRU00125, KW ECO:0000256|SAAS:SAAS00113461}; KW Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00125, KW ECO:0000256|SAAS:SAAS00516478}; KW Nucleus {ECO:0000256|PROSITE-ProRule:PRU00108, KW ECO:0000256|RuleBase:RU000682, ECO:0000256|SAAS:SAAS00474951}; KW Reference proteome {ECO:0000313|Proteomes:UP000000589}; KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00125, KW ECO:0000256|SAAS:SAAS00516446}. FT DOMAIN 26 89 LIM zinc-binding. {ECO:0000259|PROSITE: FT PS50023}. FT DOMAIN 94 154 Homeobox DNA-binding. FT {ECO:0000259|PROSITE:PS50071}. FT DNA_BIND 96 155 Homeobox. {ECO:0000256|PROSITE-ProRule: FT PRU00108}. FT NON_TER 223 223 {ECO:0000313|Ensembl:ENSMUSP00000141662}. SQ SEQUENCE 223 AA; 25374 MW; EA7890001AF5F54C CRC64; MQLADRCFSR AGSVYCKEDF FKRFGTKCTA CQQGIPPTQV VRKAQDFVYH LHCFACIICN RQLATGDEFY LMEDGRLVCK EDYETAKQND DSEAGAKRPR TTITAKQLET LKNAYKNSPK PARHVREQLS SETGLDMRVV QVWFQNRRAK EKRLKKDAGR HRWGQFYKSV KRSRGGSKQE KESSAEDCGV SDSELSFRGE QGWRGEAEAL GETLGDTNPG PQE //