ID A0A0A6YWI7_MOUSE Unreviewed; 189 AA. AC A0A0A6YWI7; DT 04-FEB-2015, integrated into UniProtKB/TrEMBL. DT 14-OCT-2015, sequence version 3. DT 14-OCT-2015, entry version 8. DE SubName: Full=Exonuclease 1 {ECO:0000313|Ensembl:ENSMUSP00000141568}; DE Flags: Fragment; GN Name=Exo1 {ECO:0000313|Ensembl:ENSMUSP00000141568, GN ECO:0000313|MGI:MGI:1349427}; OS Mus musculus (Mouse). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; OC Muroidea; Muridae; Murinae; Mus; Mus. OX NCBI_TaxID=10090 {ECO:0000313|Ensembl:ENSMUSP00000141568, ECO:0000313|Proteomes:UP000000589}; RN [1] {ECO:0000313|Ensembl:ENSMUSP00000141568, ECO:0000313|Proteomes:UP000000589} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000141568, RC ECO:0000313|Proteomes:UP000000589}; RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112; RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., RA She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., RA Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., RA Zhou S., Teague B., Potamousis K., Churas C., Place M., Herschleb J., RA Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., RA Lindblad-Toh K., Eichler E.E., Ponting C.P.; RT "Lineage-specific biology revealed by a finished genome assembly of RT the mouse."; RL PLoS Biol. 7:E1000112-E1000112(2009). RN [2] {ECO:0000313|Ensembl:ENSMUSP00000141568} RP IDENTIFICATION. RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000141568}; RG Ensembl; RL Submitted (DEC-2014) to UniProtKB. CC -!- CAUTION: The sequence shown here is derived from an Ensembl CC automatic analysis pipeline and should be considered as CC preliminary data. {ECO:0000313|Ensembl:ENSMUSP00000141568}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AC122854; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR Ensembl; ENSMUST00000193858; ENSMUSP00000141568; ENSMUSG00000039748. DR MGI; MGI:1349427; Exo1. DR Proteomes; UP000000589; Chromosome 1. DR ExpressionAtlas; A0A0A6YWI7; baseline and differential. DR GO; GO:0005654; C:nucleoplasm; ISO:MGI. DR GO; GO:0005634; C:nucleus; ISO:MGI. DR GO; GO:0035312; F:5'-3' exodeoxyribonuclease activity; ISO:MGI. DR GO; GO:0008409; F:5'-3' exonuclease activity; ISA:MGI. DR GO; GO:0003677; F:DNA binding; ISO:MGI. DR GO; GO:0051908; F:double-stranded DNA 5'-3' exodeoxyribonuclease activity; ISO:MGI. DR GO; GO:0048256; F:flap endonuclease activity; ISO:MGI. DR GO; GO:0045145; F:single-stranded DNA 5'-3' exodeoxyribonuclease activity; ISO:MGI. DR GO; GO:0043566; F:structure-specific DNA binding; IDA:MGI. DR GO; GO:0006310; P:DNA recombination; ISO:MGI. DR GO; GO:0002455; P:humoral immune response mediated by circulating immunoglobulin; IMP:MGI. DR GO; GO:0045190; P:isotype switching; IMP:MGI. DR GO; GO:0006298; P:mismatch repair; ISO:MGI. DR GO; GO:0090305; P:nucleic acid phosphodiester bond hydrolysis; ISO:MGI. DR GO; GO:0006139; P:nucleobase-containing compound metabolic process; ISA:MGI. DR GO; GO:0016446; P:somatic hypermutation of immunoglobulin genes; IMP:MGI. DR Gene3D; 3.40.50.1010; -; 2. DR InterPro; IPR029060; PIN_domain-like. DR InterPro; IPR006086; XPG-I_dom. DR InterPro; IPR006084; XPG/Rad2. DR InterPro; IPR019974; XPG_CS. DR InterPro; IPR006085; XPG_DNA_repair_N. DR PANTHER; PTHR11081; PTHR11081; 1. DR Pfam; PF00867; XPG_I; 1. DR Pfam; PF00752; XPG_N; 1. DR PRINTS; PR00853; XPGRADSUPER. DR SMART; SM00484; XPGI; 1. DR SMART; SM00485; XPGN; 1. DR SUPFAM; SSF88723; SSF88723; 1. DR PROSITE; PS00842; XPG_2; 1. PE 1: Evidence at protein level; KW Complete proteome {ECO:0000313|Proteomes:UP000000589}; KW Proteomics identification {ECO:0000213|PeptideAtlas:A0A0A6YWI7}; KW Reference proteome {ECO:0000313|Proteomes:UP000000589}. FT NON_TER 189 189 {ECO:0000313|Ensembl:ENSMUSP00000141568}. SQ SEQUENCE 189 AA; 20790 MW; 135EDB2E0C756246 CRC64; MGIQGLLQFI QEASEPVNVK KYKGQAVAVD TYCWLHKGAI ACAEKLAKGE PTDRRRQSNL LKGKQLLREG KVSEARDCFA RSINITHAMA HKVIKAARAL GVDCLVAPYE ADAQLAYLNK AGIVQAVITE DSDLLAFGCK KVILKMDQFG NGLEVDQARL GMCKQLGDVF TEEKFRYMCI LSGCDYLAS //