ID A0A0A6YWI7_MOUSE Unreviewed; 190 AA. AC A0A0A6YWI7; DT 04-FEB-2015, integrated into UniProtKB/TrEMBL. DT 27-MAY-2015, sequence version 2. DT 24-JUN-2015, entry version 6. DE SubName: Full=Exonuclease 1 {ECO:0000313|Ensembl:ENSMUSP00000141568}; DE Flags: Fragment; GN Name=Exo1 {ECO:0000313|Ensembl:ENSMUSP00000141568, GN ECO:0000313|MGI:MGI:1349427}; OS Mus musculus (Mouse). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; OC Muroidea; Muridae; Murinae; Mus; Mus. OX NCBI_TaxID=10090 {ECO:0000313|Ensembl:ENSMUSP00000141568, ECO:0000313|Proteomes:UP000000589}; RN [1] {ECO:0000313|Ensembl:ENSMUSP00000141568, ECO:0000313|Proteomes:UP000000589} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000141568, RC ECO:0000313|Proteomes:UP000000589}; RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112; RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., RA She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., RA Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., RA Zhou S., Teague B., Potamousis K., Churas C., Place M., Herschleb J., RA Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., RA Lindblad-Toh K., Eichler E.E., Ponting C.P.; RT "Lineage-specific biology revealed by a finished genome assembly of RT the mouse."; RL PLoS Biol. 7:E1000112-E1000112(2009). RN [2] {ECO:0000313|Ensembl:ENSMUSP00000141568} RP IDENTIFICATION. RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000141568}; RG Ensembl; RL Submitted (DEC-2014) to UniProtKB. CC -!- CAUTION: The sequence shown here is derived from an Ensembl CC automatic analysis pipeline and should be considered as CC preliminary data. {ECO:0000313|Ensembl:ENSMUSP00000141568}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AC122854; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR Ensembl; ENSMUST00000193858; ENSMUSP00000141568; ENSMUSG00000039748. DR MGI; MGI:1349427; Exo1. DR GeneTree; ENSGT00510000047676; -. DR Proteomes; UP000000589; Chromosome 1. DR GO; GO:0005654; C:nucleoplasm; ISO:MGI. DR GO; GO:0005634; C:nucleus; ISO:MGI. DR GO; GO:0035312; F:5'-3' exodeoxyribonuclease activity; ISO:MGI. DR GO; GO:0008409; F:5'-3' exonuclease activity; ISA:MGI. DR GO; GO:0003677; F:DNA binding; ISO:MGI. DR GO; GO:0051908; F:double-stranded DNA 5'-3' exodeoxyribonuclease activity; ISO:MGI. DR GO; GO:0048256; F:flap endonuclease activity; ISO:MGI. DR GO; GO:0045145; F:single-stranded DNA 5'-3' exodeoxyribonuclease activity; ISO:MGI. DR GO; GO:0043566; F:structure-specific DNA binding; IDA:MGI. DR GO; GO:0006310; P:DNA recombination; ISO:MGI. DR GO; GO:0002455; P:humoral immune response mediated by circulating immunoglobulin; IMP:MGI. DR GO; GO:0045190; P:isotype switching; IMP:MGI. DR GO; GO:0006298; P:mismatch repair; ISO:MGI. DR GO; GO:0090305; P:nucleic acid phosphodiester bond hydrolysis; ISO:MGI. DR GO; GO:0006139; P:nucleobase-containing compound metabolic process; ISA:MGI. DR GO; GO:0016446; P:somatic hypermutation of immunoglobulin genes; IMP:MGI. DR Gene3D; 3.40.50.1010; -; 2. DR InterPro; IPR029060; PIN_domain-like. DR InterPro; IPR006086; XPG-I_dom. DR InterPro; IPR006084; XPG/Rad2. DR InterPro; IPR019974; XPG_CS. DR InterPro; IPR006085; XPG_DNA_repair_N. DR PANTHER; PTHR11081; PTHR11081; 1. DR Pfam; PF00867; XPG_I; 1. DR Pfam; PF00752; XPG_N; 1. DR PRINTS; PR00853; XPGRADSUPER. DR SMART; SM00484; XPGI; 1. DR SMART; SM00485; XPGN; 1. DR SUPFAM; SSF88723; SSF88723; 1. DR PROSITE; PS00842; XPG_2; 1. PE 1: Evidence at protein level; KW Complete proteome {ECO:0000313|Proteomes:UP000000589}; KW Proteomics identification {ECO:0000213|PeptideAtlas:A0A0A6YWI7}; KW Reference proteome {ECO:0000313|Proteomes:UP000000589}. FT NON_TER 190 190 {ECO:0000313|Ensembl:ENSMUSP00000141568}. SQ SEQUENCE 190 AA; 20903 MW; 0EF35EDB2E0C7562 CRC64; MGIQGLLQFI QEASEPVNVK KYKGQAVAVD TYCWLHKGAI ACAEKLAKGE PTDRRRQSNL LKGKQLLREG KVSEARDCFA RSINITHAMA HKVIKAARAL GVDCLVAPYE ADAQLAYLNK AGIVQAVITE DSDLLAFGCK KVILKMDQFG NGLEVDQARL GMCKQLGDVF TEEKFRYMCI LSGCDYLASL //