ID A0A0A6YWI7_MOUSE Unreviewed; 189 AA. AC A0A0A6YWI7; DT 04-FEB-2015, integrated into UniProtKB/TrEMBL. DT 05-OCT-2016, sequence version 5. DT 12-AUG-2020, entry version 36. DE RecName: Full=Exonuclease 1 {ECO:0000256|ARBA:ARBA00020324}; DE AltName: Full=Exonuclease I {ECO:0000256|ARBA:ARBA00020302}; DE Flags: Fragment; GN Name=Exo1 {ECO:0000313|Ensembl:ENSMUSP00000141568, GN ECO:0000313|MGI:MGI:1349427}; OS Mus musculus (Mouse). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; OC Murinae; Mus; Mus. OX NCBI_TaxID=10090 {ECO:0000313|Ensembl:ENSMUSP00000141568, ECO:0000313|Proteomes:UP000000589}; RN [1] {ECO:0000313|Ensembl:ENSMUSP00000141568, ECO:0000313|Proteomes:UP000000589} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000141568, RC ECO:0000313|Proteomes:UP000000589}; RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112; RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., RA Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y., RA Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S., RA Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R., RA Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K., RA Eichler E.E., Ponting C.P.; RT "Lineage-specific biology revealed by a finished genome assembly of the RT mouse."; RL PLoS Biol. 7:E1000112-E1000112(2009). RN [2] {ECO:0000313|Ensembl:ENSMUSP00000141568} RP IDENTIFICATION. RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000141568}; RG Ensembl; RL Submitted (DEC-2014) to UniProtKB. CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AC122854; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR SMR; A0A0A6YWI7; -. DR Antibodypedia; 34705; 364 antibodies. DR Ensembl; ENSMUST00000193858; ENSMUSP00000141568; ENSMUSG00000039748. DR MGI; MGI:1349427; Exo1. DR GeneTree; ENSGT00510000047676; -. DR ChiTaRS; Exo1; mouse. DR Proteomes; UP000000589; Chromosome 1. DR Bgee; ENSMUSG00000039748; Expressed in epiblast (generic) and 234 other tissues. DR GO; GO:0035312; F:5'-3' exodeoxyribonuclease activity; IEA:InterPro. DR GO; GO:0006281; P:DNA repair; IEA:InterPro. DR InterPro; IPR032641; Exo1. DR InterPro; IPR029060; PIN-like_dom_sf. DR InterPro; IPR006086; XPG-I_dom. DR InterPro; IPR006084; XPG/Rad2. DR InterPro; IPR019974; XPG_CS. DR InterPro; IPR006085; XPG_DNA_repair_N. DR PANTHER; PTHR11081; PTHR11081; 2. DR PANTHER; PTHR11081:SF53; PTHR11081:SF53; 2. DR Pfam; PF00867; XPG_I; 1. DR Pfam; PF00752; XPG_N; 1. DR PRINTS; PR00853; XPGRADSUPER. DR SMART; SM00484; XPGI; 1. DR SMART; SM00485; XPGN; 1. DR SUPFAM; SSF88723; SSF88723; 1. DR PROSITE; PS00842; XPG_2; 1. PE 1: Evidence at protein level; KW DNA damage {ECO:0000256|ARBA:ARBA00022763}; KW DNA excision {ECO:0000256|ARBA:ARBA00022769}; KW DNA repair {ECO:0000256|ARBA:ARBA00023204}; KW Proteomics identification {ECO:0000213|EPD:A0A0A6YWI7}; KW Reference proteome {ECO:0000313|Proteomes:UP000000589}. FT DOMAIN 1..83 FT /note="XPGN" FT /evidence="ECO:0000259|SMART:SM00485" FT DOMAIN 98..168 FT /note="XPGI" FT /evidence="ECO:0000259|SMART:SM00484" FT NON_TER 189 FT /evidence="ECO:0000313|Ensembl:ENSMUSP00000141568" SQ SEQUENCE 189 AA; 20790 MW; 135EDB2E0C756246 CRC64; MGIQGLLQFI QEASEPVNVK KYKGQAVAVD TYCWLHKGAI ACAEKLAKGE PTDRRRQSNL LKGKQLLREG KVSEARDCFA RSINITHAMA HKVIKAARAL GVDCLVAPYE ADAQLAYLNK AGIVQAVITE DSDLLAFGCK KVILKMDQFG NGLEVDQARL GMCKQLGDVF TEEKFRYMCI LSGCDYLAS //