ID A0A0A6YWI7_MOUSE Unreviewed; 189 AA. AC A0A0A6YWI7; DT 04-FEB-2015, integrated into UniProtKB/TrEMBL. DT 05-OCT-2016, sequence version 5. DT 12-SEP-2018, entry version 27. DE SubName: Full=Exonuclease 1 {ECO:0000313|Ensembl:ENSMUSP00000141568}; DE Flags: Fragment; GN Name=Exo1 {ECO:0000313|Ensembl:ENSMUSP00000141568, GN ECO:0000313|MGI:MGI:1349427}; OS Mus musculus (Mouse). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; OC Muroidea; Muridae; Murinae; Mus; Mus. OX NCBI_TaxID=10090 {ECO:0000313|Ensembl:ENSMUSP00000141568, ECO:0000313|Proteomes:UP000000589}; RN [1] {ECO:0000313|Ensembl:ENSMUSP00000141568, ECO:0000313|Proteomes:UP000000589} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000141568, RC ECO:0000313|Proteomes:UP000000589}; RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112; RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., RA She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., RA Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., RA Zhou S., Teague B., Potamousis K., Churas C., Place M., Herschleb J., RA Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., RA Lindblad-Toh K., Eichler E.E., Ponting C.P.; RT "Lineage-specific biology revealed by a finished genome assembly of RT the mouse."; RL PLoS Biol. 7:E1000112-E1000112(2009). RN [2] {ECO:0000313|Ensembl:ENSMUSP00000141568} RP IDENTIFICATION. RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000141568}; RG Ensembl; RL Submitted (DEC-2014) to UniProtKB. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AC122854; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR Ensembl; ENSMUST00000193858; ENSMUSP00000141568; ENSMUSG00000039748. DR MGI; MGI:1349427; Exo1. DR GeneTree; ENSGT00510000047676; -. DR Proteomes; UP000000589; Chromosome 1. DR Bgee; ENSMUSG00000039748; Expressed in 216 organ(s), highest expression level in primary oocyte. DR ExpressionAtlas; A0A0A6YWI7; baseline and differential. DR GO; GO:0035312; F:5'-3' exodeoxyribonuclease activity; IEA:InterPro. DR GO; GO:0003682; F:chromatin binding; IEA:Ensembl. DR GO; GO:0006281; P:DNA repair; IEA:InterPro. DR GO; GO:0002455; P:humoral immune response mediated by circulating immunoglobulin; IEA:Ensembl. DR GO; GO:0045190; P:isotype switching; IEA:Ensembl. DR GO; GO:0016446; P:somatic hypermutation of immunoglobulin genes; IEA:Ensembl. DR InterPro; IPR032641; Exo1. DR InterPro; IPR029060; PIN-like_dom_sf. DR InterPro; IPR006086; XPG-I_dom. DR InterPro; IPR006084; XPG/Rad2. DR InterPro; IPR019974; XPG_CS. DR InterPro; IPR006085; XPG_DNA_repair_N. DR PANTHER; PTHR11081; PTHR11081; 2. DR PANTHER; PTHR11081:SF8; PTHR11081:SF8; 2. DR Pfam; PF00867; XPG_I; 1. DR Pfam; PF00752; XPG_N; 1. DR PRINTS; PR00853; XPGRADSUPER. DR SMART; SM00484; XPGI; 1. DR SMART; SM00485; XPGN; 1. DR SUPFAM; SSF88723; SSF88723; 1. DR PROSITE; PS00842; XPG_2; 1. PE 1: Evidence at protein level; KW Complete proteome {ECO:0000313|Proteomes:UP000000589}; KW Proteomics identification {ECO:0000213|EPD:A0A0A6YWI7}; KW Reference proteome {ECO:0000313|Proteomes:UP000000589}. FT DOMAIN 1 83 XPGN. {ECO:0000259|SMART:SM00485}. FT DOMAIN 98 168 XPGI. {ECO:0000259|SMART:SM00484}. FT NON_TER 189 189 {ECO:0000313|Ensembl:ENSMUSP00000141568}. SQ SEQUENCE 189 AA; 20790 MW; 135EDB2E0C756246 CRC64; MGIQGLLQFI QEASEPVNVK KYKGQAVAVD TYCWLHKGAI ACAEKLAKGE PTDRRRQSNL LKGKQLLREG KVSEARDCFA RSINITHAMA HKVIKAARAL GVDCLVAPYE ADAQLAYLNK AGIVQAVITE DSDLLAFGCK KVILKMDQFG NGLEVDQARL GMCKQLGDVF TEEKFRYMCI LSGCDYLAS //