ID A0A0A6N947_9THEM Unreviewed; 577 AA. AC A0A0A6N947; DT 04-FEB-2015, integrated into UniProtKB/TrEMBL. DT 04-FEB-2015, sequence version 1. DT 03-MAY-2023, entry version 30. DE SubName: Full=ABC transporter {ECO:0000313|EMBL:KHC94043.1}; GN ORFNames=Mc24_00685 {ECO:0000313|EMBL:KHC94043.1}; OS Thermotoga sp. Mc24. OC Bacteria; Thermotogae; Thermotogales; Thermotogaceae; Thermotoga. OX NCBI_TaxID=1231241 {ECO:0000313|EMBL:KHC94043.1, ECO:0000313|Proteomes:UP000030509}; RN [1] {ECO:0000313|EMBL:KHC94043.1, ECO:0000313|Proteomes:UP000030509} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Mc24 {ECO:0000313|EMBL:KHC94043.1, RC ECO:0000313|Proteomes:UP000030509}; RA Nesbo C.L., Dlutek M., Marquis P., Bonch-Osmolovskaya E., Ilya K., RA Doolittle F.W.; RT "Genomes of Thermotoga isolates."; RL Submitted (SEP-2012) to the EMBL/GenBank/DDBJ databases. CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi- CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}. CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ CC whole genome shotgun (WGS) entry which is preliminary data. CC {ECO:0000313|EMBL:KHC94043.1}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; JSFH01000002; KHC94043.1; -; Genomic_DNA. DR RefSeq; WP_012896234.1; NZ_JSFH01000002.1. DR AlphaFoldDB; A0A0A6N947; -. DR STRING; 1231241.Mc24_00685; -. DR EnsemblBacteria; KHC94043; KHC94043; Mc24_00685. DR PATRIC; fig|1231241.4.peg.145; -. DR eggNOG; COG1132; Bacteria. DR Proteomes; UP000030509; Unassembled WGS sequence. DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell. DR GO; GO:0140359; F:ABC-type transporter activity; IEA:InterPro. DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW. DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro. DR CDD; cd18548; ABC_6TM_Tm287_like; 1. DR Gene3D; 1.20.1560.10; ABC transporter type 1, transmembrane domain; 1. DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1. DR InterPro; IPR003593; AAA+_ATPase. DR InterPro; IPR011527; ABC1_TM_dom. DR InterPro; IPR036640; ABC1_TM_sf. DR InterPro; IPR003439; ABC_transporter-like_ATP-bd. DR InterPro; IPR017871; ABC_transporter-like_CS. DR InterPro; IPR027417; P-loop_NTPase. DR InterPro; IPR039421; Type_1_exporter. DR PANTHER; PTHR43394; ATP-DEPENDENT PERMEASE MDL1, MITOCHONDRIAL; 1. DR PANTHER; PTHR43394:SF1; ATP-DEPENDENT PERMEASE MDL1, MITOCHONDRIAL; 1. DR Pfam; PF00664; ABC_membrane; 1. DR Pfam; PF00005; ABC_tran; 1. DR SMART; SM00382; AAA; 1. DR SUPFAM; SSF90123; ABC transporter transmembrane region; 1. DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1. DR PROSITE; PS50929; ABC_TM1F; 1. DR PROSITE; PS00211; ABC_TRANSPORTER_1; 1. DR PROSITE; PS50893; ABC_TRANSPORTER_2; 1. PE 4: Predicted; KW ATP-binding {ECO:0000256|ARBA:ARBA00022840}; KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius}; KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741}; KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius}; KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989, KW ECO:0000256|SAM:Phobius}. FT TRANSMEM 12..36 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT TRANSMEM 56..80 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT TRANSMEM 133..151 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT TRANSMEM 157..174 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT TRANSMEM 229..258 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT TRANSMEM 278..297 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT DOMAIN 16..298 FT /note="ABC transmembrane type-1" FT /evidence="ECO:0000259|PROSITE:PS50929" FT DOMAIN 332..567 FT /note="ABC transporter" FT /evidence="ECO:0000259|PROSITE:PS50893" SQ SEQUENCE 577 AA; 64407 MW; 723F687A57655F13 CRC64; MKTLARYLKP YWLFAVLAPL FMVVEVICDL SQPTLLARIV DEGIARGDFS LVLKTGILML IVALIGAVGG IGCTVFASYA SQNFGADLRR DLFRKVLSFS ISNVNRFHTS SLITRLTNDV TQLQNLVMML LRIVVRAPLL FVGGIVMAVS INVKLSSVLI FLIPPIVLLF VWLTKKGNPL FRKIQESTDE VNRVVRENLL GVRVVRAFRR EEYENENFRK ANESLRRSII SAFSLIVFAL PLFIFIVNMG MIAVLWFGGV LVRNNQMEIG SIMAYTNYLM QIMFSLMMIG NILNFIVRAS ASAKRVLEVL NEKPAIEEAD NALALPNVEG SVSFENVEFR YFENTDPVLS GVNFSVEPGS LVAVLGETGS GKTTLMSLIP RLIDPERGRV EVDELDVRTV KLKDLRSHIS VVPQETVLFS GTIKENLKWG REDATDDEIV EAAKIAQIHD FIISLPEGYD SRVERGGRNF SGGQKQRLSI ARALVKKPKV LILDDCTSSV DPITEKRILD GLKRYTKGCT TFIITQKIPT ALLADKILVL HEGKVAGFGT HKELLEHCKP YREIYESQFG NGVMNDA //