ID A0A097C6W9_9COLE Unreviewed; 219 AA.
AC A0A097C6W9;
DT 07-JAN-2015, integrated into UniProtKB/TrEMBL.
DT 07-JAN-2015, sequence version 1.
DT 29-APR-2015, entry version 4.
DE RecName: Full=Cytochrome c oxidase subunit 1 {ECO:0000256|RuleBase:RU000369};
DE EC=1.9.3.1 {ECO:0000256|RuleBase:RU000369};
DE Flags: Fragment;
GN Name=COI {ECO:0000313|EMBL:AIS77891.1};
OS Anisotoma humeralis.
OG Mitochondrion {ECO:0000313|EMBL:AIS77891.1}.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
OC Pterygota; Neoptera; Endopterygota; Coleoptera; Polyphaga;
OC Staphyliniformia; Leiodidae; Leiodinae.
OX NCBI_TaxID=355579 {ECO:0000313|EMBL:AIS77891.1};
RN [1] {ECO:0000313|EMBL:AJB85687.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=25469559;
RA Hendrich L., Moriniere J., Haszprunar G., Hebert P.D., Hausmann A.,
RA Kohler F., Balke M.;
RT "A comprehensive DNA barcode database for Central European beetles
RT with a focus on Germany: Adding more than 3,500 identified species to
RT BOLD.";
RL Mol. Ecol. Resour. 0:0-0(2014).
RN [2] {ECO:0000313|EMBL:AIS77891.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=25255319;
RA Pentinsaari M., Hebert P.D., Mutanen M.;
RT "Barcoding beetles: a regional survey of 1872 species reveals high
RT identification success and unusually deep interspecific divergences.";
RL PLoS ONE 9:E108651-E108651(2014).
CC -!- FUNCTION: Cytochrome c oxidase is the component of the respiratory
CC chain that catalyzes the reduction of oxygen to water. Subunits 1-
CC 3 form the functional core of the enzyme complex. CO I is the
CC catalytic subunit of the enzyme. Electrons originating in
CC cytochrome c are transferred via the copper A center of subunit 2
CC and heme A of subunit 1 to the bimetallic center formed by heme A3
CC and copper B. {ECO:0000256|RuleBase:RU000369}.
CC -!- CATALYTIC ACTIVITY: 4 ferrocytochrome c + O(2) + 4 H(+) = 4
CC ferricytochrome c + 2 H(2)O. {ECO:0000256|RuleBase:RU000369}.
CC -!- PATHWAY: Energy metabolism; oxidative phosphorylation.
CC {ECO:0000256|RuleBase:RU000369}.
CC -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane
CC {ECO:0000256|RuleBase:RU000369}; Multi-pass membrane protein
CC {ECO:0000256|RuleBase:RU000369}.
CC -!- SIMILARITY: Belongs to the heme-copper respiratory oxidase family.
CC {ECO:0000256|RuleBase:RU000369}.
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DR EMBL; KJ962141; AIS77057.1; -; Genomic_DNA.
DR EMBL; KJ962690; AIS77606.1; -; Genomic_DNA.
DR EMBL; KJ962975; AIS77891.1; -; Genomic_DNA.
DR EMBL; KM439972; AJB85687.1; -; Genomic_DNA.
DR EMBL; KM443088; AJB88803.1; -; Genomic_DNA.
DR EMBL; KM443591; AJB89306.1; -; Genomic_DNA.
DR EMBL; KM451176; AJB96891.1; -; Genomic_DNA.
DR EMBL; KM452262; AJB97977.1; -; Genomic_DNA.
DR UniPathway; UPA00705; -.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0070469; C:respiratory chain; IEA:UniProtKB-KW.
DR GO; GO:0004129; F:cytochrome-c oxidase activity; IEA:InterPro.
DR GO; GO:0020037; F:heme binding; IEA:InterPro.
DR GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR GO; GO:0009060; P:aerobic respiration; IEA:InterPro.
DR GO; GO:0006119; P:oxidative phosphorylation; IEA:UniProtKB-UniPathway.
DR Gene3D; 1.20.210.10; -; 1.
DR InterPro; IPR000883; COX1.
DR InterPro; IPR023616; Cyt_c_Oxase_su1_dom.
DR PANTHER; PTHR10422; PTHR10422; 1.
DR Pfam; PF00115; COX1; 1.
DR PRINTS; PR01165; CYCOXIDASEI.
DR SUPFAM; SSF81442; SSF81442; 1.
DR PROSITE; PS50855; COX1; 1.
PE 3: Inferred from homology;
KW Copper {ECO:0000256|RuleBase:RU000369};
KW Electron transport {ECO:0000256|RuleBase:RU000369};
KW Heme {ECO:0000256|RuleBase:RU000369};
KW Iron {ECO:0000256|RuleBase:RU000369};
KW Membrane {ECO:0000256|RuleBase:RU000369};
KW Metal-binding {ECO:0000256|RuleBase:RU000369};
KW Mitochondrion {ECO:0000256|RuleBase:RU000369,
KW ECO:0000313|EMBL:AIS77891.1};
KW Mitochondrion inner membrane {ECO:0000256|RuleBase:RU000369};
KW Oxidoreductase {ECO:0000256|RuleBase:RU000369};
KW Respiratory chain {ECO:0000256|RuleBase:RU000369};
KW Transmembrane {ECO:0000256|RuleBase:RU000369};
KW Transport {ECO:0000256|RuleBase:RU000369}.
FT NON_TER 1 1 {ECO:0000313|EMBL:AIS77891.1}.
FT NON_TER 219 219 {ECO:0000313|EMBL:AIS77891.1}.
SQ SEQUENCE 219 AA; 23597 MW; F503CE3F85564173 CRC64;
TLYFIFGAWS GMVGTSLSIL IRAELGTPGS LIGDDQIYNV IVTAHAFVMI FFMVMPIMIG
GFGNWLVPLM LGAPDMAFPR MNNMSFWLLP PSLTLLLMSS MVENGAGTGW TVYPPLSANI
SHSGSSVDLA IFSLHLAGIS SILGAVNFIT TVINMRSIGM TFDKMPLFVW SVVITALLLL
LSLPVLAGAI TMLLTDRNLN TSFFDPAGGG DPILYQHLF
//