ID A0A096ML87_PAPAN Unreviewed; 1063 AA. AC A0A096ML87; DT 26-NOV-2014, integrated into UniProtKB/TrEMBL. DT 26-NOV-2014, sequence version 1. DT 13-FEB-2019, entry version 30. DE SubName: Full=Lysine demethylase 4A {ECO:0000313|Ensembl:ENSPANP00000000299}; GN Name=KDM4A {ECO:0000313|Ensembl:ENSPANP00000000299}; OS Papio anubis (Olive baboon). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; OC Catarrhini; Cercopithecidae; Cercopithecinae; Papio. OX NCBI_TaxID=9555 {ECO:0000313|Ensembl:ENSPANP00000000299, ECO:0000313|Proteomes:UP000028761}; RN [1] {ECO:0000313|Ensembl:ENSPANP00000000299, ECO:0000313|Proteomes:UP000028761} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RA Liu Y.L., Abraham K.A., Akbar H.A., Ali S.A., Anosike U.A., RA Aqrawi P.A., Arias F.A., Attaway T.A., Awwad R.A., Babu C.B., RA Bandaranaike D.B., Battles P.B., Bell A.B., Beltran B.B., RA Berhane-Mersha D.B., Bess C.B., Bickham C.B., Bolden T.B., RA Carter K.C., Chau D.C., Chavez A.C., Clerc-Blankenburg K.C., RA Coyle M.C., Dao M.D., Davila M.L.D., Davy-Carroll L.D., Denson S.D., RA Dinh H.D., Fernandez S.F., Fernando P.F., Forbes L.F., Francis C.F., RA Francisco L.F., Fu Q.F., Garcia-Iii R.G., Garrett T.G., Gross S.G., RA Gubbala S.G., Hirani K.H., Hogues M.H., Hollins B.H., Jackson L.J., RA Javaid M.J., Jhangiani S.J., Johnson A.J., Johnson B.J., Jones J.J., RA Joshi V.J., Kalu J.K., Khan N.K., Korchina V.K., Kovar C.K., RA Lago L.L., Lara F.L., Le T.-K.L., Lee S.L., Legall-Iii F.L., RA Lemon S.L., Liu J.L., Liu Y.-S.L., Liyanage D.L., Lopez J.L., RA Lorensuhewa L.L., Mata R.M., Mathew T.M., Mercado C.M., Mercado I.M., RA Morales K.M., Morgan M.M., Munidasa M.M., Ngo D.N., Nguyen L.N., RA Nguyen T.N., Nguyen N.N., Obregon M.O., Okwuonu G.O., Ongeri F.O., RA Onwere C.O., Osifeso I.O., Parra A.P., Patil S.P., Perez A.P., RA Perez Y.P., Pham C.P., Pu L.-L.P., Puazo M.P., Quiroz J.Q., RA Rouhana J.R., Ruiz M.R., Ruiz S.-J.R., Saada N.S., Santibanez J.S., RA Scheel M.S., Schneider B.S., Simmons D.S., Sisson I.S., Tang L.-Y.T., RA Thornton R.T., Tisius J.T., Toledanes G.T., Trejos Z.T., Usmani K.U., RA Varghese R.V., Vattathil S.V., Vee V.V., Walker D.W., RA Weissenberger G.W., White C.W., Williams A.W., Woodworth J.W., RA Wright R.W., Zhu Y.Z., Han Y.H., Newsham I.N., Nazareth L.N., RA Worley K.W., Muzny D.M., Rogers J.R., Gibbs R.G.; RT "Whole Genome Assembly of Papio anubis."; RL Submitted (MAR-2012) to the EMBL/GenBank/DDBJ databases. RN [2] {ECO:0000313|Ensembl:ENSPANP00000000299} RP IDENTIFICATION. RG Ensembl; RL Submitted (OCT-2014) to the EMBL/GenBank/DDBJ databases. CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|SAAS:SAAS01133602}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AHZZ02015883; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR RefSeq; XP_003891797.1; XM_003891748.2. DR RefSeq; XP_009205076.1; XM_009206812.1. DR Ensembl; ENSPANT00000004156; ENSPANP00000000299; ENSPANG00000013120. DR GeneID; 101010163; -. DR CTD; 9682; -. DR GeneTree; ENSGT00940000159643; -. DR OMA; TAGCCVQ; -. DR OrthoDB; 1186832at2759; -. DR Proteomes; UP000028761; Chromosome 1. DR GO; GO:0005829; C:cytosol; IEA:Ensembl. DR GO; GO:0001650; C:fibrillar center; IEA:Ensembl. DR GO; GO:0005721; C:pericentric heterochromatin; IEA:Ensembl. DR GO; GO:0051864; F:histone demethylase activity (H3-K36 specific); IEA:Ensembl. DR GO; GO:0032454; F:histone demethylase activity (H3-K9 specific); IEA:Ensembl. DR GO; GO:0035064; F:methylated histone binding; IEA:Ensembl. DR GO; GO:0031625; F:ubiquitin protein ligase binding; IEA:Ensembl. DR GO; GO:0008270; F:zinc ion binding; IEA:Ensembl. DR GO; GO:0014898; P:cardiac muscle hypertrophy in response to stress; IEA:Ensembl. DR GO; GO:0010507; P:negative regulation of autophagy; IEA:Ensembl. DR GO; GO:1900113; P:negative regulation of histone H3-K9 trimethylation; IEA:Ensembl. DR GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IEA:Ensembl. DR Gene3D; 3.30.40.10; -; 2. DR InterPro; IPR034732; EPHD. DR InterPro; IPR003347; JmjC_dom. DR InterPro; IPR003349; JmjN. DR InterPro; IPR040477; KDM4_Tudor_2. DR InterPro; IPR002999; Tudor. DR InterPro; IPR011011; Znf_FYVE_PHD. DR InterPro; IPR001965; Znf_PHD. DR InterPro; IPR013083; Znf_RING/FYVE/PHD. DR Pfam; PF02373; JmjC; 1. DR Pfam; PF02375; JmjN; 1. DR Pfam; PF18104; Tudor_2; 2. DR SMART; SM00558; JmjC; 1. DR SMART; SM00545; JmjN; 1. DR SMART; SM00249; PHD; 2. DR SMART; SM00333; TUDOR; 2. DR SUPFAM; SSF57903; SSF57903; 1. DR PROSITE; PS51805; EPHD; 1. DR PROSITE; PS51184; JMJC; 1. DR PROSITE; PS51183; JMJN; 1. PE 4: Predicted; KW Coiled coil {ECO:0000256|SAM:Coils}; KW Complete proteome {ECO:0000313|Proteomes:UP000028761}; KW Metal-binding {ECO:0000256|SAAS:SAAS01011399}; KW Nucleus {ECO:0000256|SAAS:SAAS01133601}; KW Reference proteome {ECO:0000313|Proteomes:UP000028761}; KW Zinc {ECO:0000256|SAAS:SAAS01006535}; KW Zinc-finger {ECO:0000256|SAAS:SAAS01007077}. FT DOMAIN 14 56 JmjN. {ECO:0000259|PROSITE:PS51183}. FT DOMAIN 142 308 JmjC. {ECO:0000259|PROSITE:PS51184}. FT DOMAIN 771 884 PHD-type. {ECO:0000259|PROSITE:PS51805}. FT COILED 462 489 {ECO:0000256|SAM:Coils}. SQ SEQUENCE 1063 AA; 120606 MW; 9CDCE99EBBEB9128 CRC64; MASESETLNP SARIMTFYPT MEEFRNFSRY IAYIESQGAH RAGLAKVVPP KEWKPRASYD DIDDLVIPAP IQQLVTGQSG LFTQYNIQKK AMTVREFRKI ANSDKYCTPR YSEFEELERK YWKNLTFNPP IYGADVNGTL YEKHVDEWNI GRLRTILDLV EKESGITIEG VNTPYLYFGM WKTSFAWHTE DMDLYSINYL HFGEPKSWYS VPPEHGKRLE RLAKGFFPGS AQSCEAFLRH KMTLISPLML KKYGIPFDKV TQEAGEFMIT FPYGYHAGFN HGFNCAESTN FATRRWIEYG KQAVLCSCRK DMVKISMDVF VRKFQPERYK LWKAGKDNTV IDHTLPTPEA AEFLKESELP PRAGNEEECP EEDMEGVEDG EEGDLKTSLA KHRIGTKRHR VCLEIPQEVS QSELFPKEEL SSEQYEMTEC PAALAPVRPT HSSVRQVEDG LTFPDYSDST EVKFEELKNV KLEEEDEEEE QEAAALDLSV NPASVGGRLV FSGSQKKSPS LGSGSSRDSI SSDSETSEPL SCRAQGQTGV LTVHSYAKGD GRVTVGEPCM RKKGSAARSI SERELAEVAD EYMFSLEENK KSKGRRQPLS KLPRHHPLVL QECVSDDETS EQLTPEEEAE ETEAWAKPLS QLWQNRPPNF EAEKEFNETM AQQAPHCAVC MIFQTYHQVE FGGFTQNCGN ASDLAPQKQR TKPLIPEMCF TSTGCSTDIN LSTPYLEEDG TSILVSCKKC SVRVHASCYG VPPAKASEDW MCSRCSANAL EEDCCLCSLR GGALQRANDD RWVHVSCAVA ILEARFVNIA ERSPVDVSKI PLPRFKLKCI FCKKRRKRTA GCCVQCSHGR CPTAFHVSCA QAAGVMMQPD DWPFVVFITC FRHKIPNLER AKGALQSITA GQKVISKHKN GRFYQCEVVR LTTETFYEVN FDDGSFSDNL YPEDIVSQDC LQLGPPAEGE VVQVRWTDGQ VYGAKFVASH PIQMYQVEFE DGSQLVVKRD DVYTLDEELP KRVKSRLSVA SDMRFNEIFT EKEVKQEKKR QRVINSRYRE DYIEPALYRA IME //