ID A0A096LXN5_POEFO Unreviewed; 636 AA. AC A0A096LXN5; DT 26-NOV-2014, integrated into UniProtKB/TrEMBL. DT 26-NOV-2014, sequence version 1. DT 29-MAY-2024, entry version 44. DE RecName: Full=DNA-directed RNA polymerase subunit {ECO:0000256|RuleBase:RU004279}; DE EC=2.7.7.6 {ECO:0000256|RuleBase:RU004279}; OS Poecilia formosa (Amazon molly) (Limia formosa). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata; OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae; OC Poecilia. OX NCBI_TaxID=48698 {ECO:0000313|Ensembl:ENSPFOP00000023926.1, ECO:0000313|Proteomes:UP000028760}; RN [1] {ECO:0000313|Proteomes:UP000028760} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=female {ECO:0000313|Proteomes:UP000028760}; RA Schartl M., Warren W.; RL Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases. RN [2] {ECO:0000313|Ensembl:ENSPFOP00000023926.1} RP IDENTIFICATION. RG Ensembl; RL Submitted (SEP-2023) to UniProtKB. CC -!- FUNCTION: DNA-dependent RNA polymerase catalyzes the transcription of CC DNA into RNA using the four ribonucleoside triphosphates as substrates. CC {ECO:0000256|RuleBase:RU004279}. CC -!- CATALYTIC ACTIVITY: CC Reaction=a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + CC RNA(n+1); Xref=Rhea:RHEA:21248, Rhea:RHEA-COMP:14527, Rhea:RHEA- CC COMP:17342, ChEBI:CHEBI:33019, ChEBI:CHEBI:61557, ChEBI:CHEBI:140395; CC EC=2.7.7.6; Evidence={ECO:0000256|RuleBase:RU004279}; CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}. CC -!- SIMILARITY: Belongs to the RNA polymerase beta' chain family. CC {ECO:0000256|ARBA:ARBA00006460, ECO:0000256|RuleBase:RU004279}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AYCK01007293; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR AlphaFoldDB; A0A096LXN5; -. DR Ensembl; ENSPFOT00000031637.1; ENSPFOP00000023926.1; ENSPFOG00000021951.1. DR eggNOG; KOG0261; Eukaryota. DR GeneTree; ENSGT00930000151028; -. DR Proteomes; UP000028760; Unassembled WGS sequence. DR GO; GO:0031981; C:nuclear lumen; IEA:UniProt. DR GO; GO:0005666; C:RNA polymerase III complex; IEA:TreeGrafter. DR GO; GO:0003677; F:DNA binding; IEA:InterPro. DR GO; GO:0001056; F:RNA polymerase III activity; IEA:TreeGrafter. DR CDD; cd02583; RNAP_III_RPC1_N; 1. DR Gene3D; 2.40.40.20; -; 1. DR Gene3D; 3.30.1490.180; RNA polymerase ii; 1. DR Gene3D; 4.10.860.120; RNA polymerase II, clamp domain; 1. DR Gene3D; 1.10.274.100; RNA polymerase Rpb1, domain 3; 1. DR InterPro; IPR045867; DNA-dir_RpoC_beta_prime. DR InterPro; IPR000722; RNA_pol_asu. DR InterPro; IPR006592; RNA_pol_N. DR InterPro; IPR007080; RNA_pol_Rpb1_1. DR InterPro; IPR007066; RNA_pol_Rpb1_3. DR InterPro; IPR042102; RNA_pol_Rpb1_3_sf. DR InterPro; IPR044893; RNA_pol_Rpb1_clamp_domain. DR InterPro; IPR035697; RNAP_III_RPC1_N. DR PANTHER; PTHR19376; DNA-DIRECTED RNA POLYMERASE; 1. DR PANTHER; PTHR19376:SF32; DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC1; 1. DR Pfam; PF04997; RNA_pol_Rpb1_1; 1. DR Pfam; PF00623; RNA_pol_Rpb1_2; 1. DR Pfam; PF04983; RNA_pol_Rpb1_3; 1. DR SMART; SM00663; RPOLA_N; 1. DR SUPFAM; SSF64484; beta and beta-prime subunits of DNA dependent RNA-polymerase; 1. PE 3: Inferred from homology; KW DNA-directed RNA polymerase {ECO:0000256|ARBA:ARBA00022478, KW ECO:0000256|RuleBase:RU004279}; KW Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695, KW ECO:0000256|RuleBase:RU004279}; Nucleus {ECO:0000256|ARBA:ARBA00023242}; KW Reference proteome {ECO:0000313|Proteomes:UP000028760}; KW Transcription {ECO:0000256|ARBA:ARBA00023163, KW ECO:0000256|RuleBase:RU004279}; KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|RuleBase:RU004279}. FT DOMAIN 248..553 FT /note="RNA polymerase N-terminal" FT /evidence="ECO:0000259|SMART:SM00663" SQ SEQUENCE 636 AA; 72137 MW; A3A23FE7DABCB55B CRC64; MVKEQFRETD VAKKISHICF GMKSAEQMRK QAHIQVVSKN LYSQDNKRTP LPYGVLDHRM GTSEKDRPCL TCGKNLADCL GHYGYLDLEL PCFHVGYFKA VIGILQMICK TCSSIMLTKE DKQQFMDYLK RPNLAYLQKR GLKKKISDKC RKRTICLNCG AFNGSVKKCG LLKIIHEKYK TTKKVVEPFV SDFLQSFDIA IEHNKLMEPL LPRAQENLNP LVVLNLFRRI PAEDIPLLLM NPEAGKPADL IITRLLVPPL CIRPSVVSDL KSGTNEDDLT MKLTEIIFLN DVIKKHRMTG AKTQMIMEDW DFLQLQCALY INSELSGIPL NMAPKKWTRG FVQRLKGKQG RFRGNLSGKR VDFSGRTVIS PDPNLRIDEV AVPVHVAKIL TYPEKVNKAN LELMRKLVRN GPDVHPGANF IQTRHTQIKR FLKYGNREKI AQELRIGDVV ERHLIDGDIV LFNRQPSLHK LSIMAHIAKV KPHRTFRFNE CVCTPYNADF DGDEMNLHLP QTEEAKAEAL VLMGTKANLV TPRNGEPLIA AIQDFLTGAY LLTLKDTFFD RSKACQIVAS ILVGKDEKIR ISLPRPAIIK PIALWTGKQI FSVILKPSKD CPVNANLRTK GKQYCGKGED LCHNDS //