ID A0A091X520_NIPNI Unreviewed; 937 AA. AC A0A091X520; DT 26-NOV-2014, integrated into UniProtKB/TrEMBL. DT 26-NOV-2014, sequence version 1. DT 02-JUN-2021, entry version 40. DE RecName: Full=Nuclear factor NF-kappa-B p105 subunit {ECO:0000256|ARBA:ARBA00020838}; DE AltName: Full=Nuclear factor NF-kappa-B p50 subunit {ECO:0000256|ARBA:ARBA00014498}; DE AltName: Full=Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 {ECO:0000256|ARBA:ARBA00017723}; DE Flags: Fragment; GN ORFNames=Y956_00943 {ECO:0000313|EMBL:KFR08581.1}; OS Nipponia nippon (Crested ibis) (Ibis nippon). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; OC Coelurosauria; Aves; Neognathae; Pelecaniformes; Threskiornithidae; OC Nipponia. OX NCBI_TaxID=128390 {ECO:0000313|EMBL:KFR08581.1, ECO:0000313|Proteomes:UP000053283}; RN [1] {ECO:0000313|EMBL:KFR08581.1, ECO:0000313|Proteomes:UP000053283} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=BGI_Y956 {ECO:0000313|EMBL:KFR08581.1}; RA Zhang G., Li C.; RT "Genome evolution of avian class."; RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases. CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}. CC Nucleus {ECO:0000256|ARBA:ARBA00004123}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; KL411536; KFR08581.1; -; Genomic_DNA. DR STRING; 128390.XP_009472960.1; -. DR eggNOG; KOG0504; Eukaryota. DR Proteomes; UP000053283; Unassembled WGS sequence. DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW. DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro. DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IEA:InterPro. DR GO; GO:0007165; P:signal transduction; IEA:InterPro. DR CDD; cd01177; IPT_NFkappaB; 1. DR Gene3D; 1.25.40.20; -; 1. DR Gene3D; 2.60.40.10; -; 1. DR Gene3D; 2.60.40.340; -; 1. DR InterPro; IPR002110; Ankyrin_rpt. DR InterPro; IPR020683; Ankyrin_rpt-contain_dom. DR InterPro; IPR036770; Ankyrin_rpt-contain_sf. DR InterPro; IPR011029; DEATH-like_dom_sf. DR InterPro; IPR000488; Death_domain. DR InterPro; IPR013783; Ig-like_fold. DR InterPro; IPR014756; Ig_E-set. DR InterPro; IPR002909; IPT_dom. DR InterPro; IPR033926; IPT_NFkappaB. DR InterPro; IPR030503; NF-kB_p105. DR InterPro; IPR000451; NFkB/Dor. DR InterPro; IPR008967; p53-like_TF_DNA-bd. DR InterPro; IPR030492; RHD_CS. DR InterPro; IPR032397; RHD_dimer. DR InterPro; IPR011539; RHD_DNA_bind_dom. DR InterPro; IPR037059; RHD_DNA_bind_dom_sf. DR PANTHER; PTHR24169; PTHR24169; 1. DR PANTHER; PTHR24169:SF9; PTHR24169:SF9; 1. DR Pfam; PF12796; Ank_2; 1. DR Pfam; PF00531; Death; 1. DR Pfam; PF16179; RHD_dimer; 1. DR Pfam; PF00554; RHD_DNA_bind; 1. DR PRINTS; PR00057; NFKBTNSCPFCT. DR SMART; SM00248; ANK; 6. DR SMART; SM00005; DEATH; 1. DR SMART; SM00429; IPT; 1. DR SUPFAM; SSF47986; SSF47986; 1. DR SUPFAM; SSF48403; SSF48403; 1. DR SUPFAM; SSF49417; SSF49417; 1. DR SUPFAM; SSF81296; SSF81296; 1. DR PROSITE; PS50297; ANK_REP_REGION; 1. DR PROSITE; PS50088; ANK_REPEAT; 6. DR PROSITE; PS01204; REL_1; 1. DR PROSITE; PS50254; REL_2; 1. PE 4: Predicted; KW Activator {ECO:0000256|ARBA:ARBA00023159}; KW ANK repeat {ECO:0000256|ARBA:ARBA00023043, ECO:0000256|PROSITE- KW ProRule:PRU00023}; DNA-binding {ECO:0000256|ARBA:ARBA00023125}; KW Nucleus {ECO:0000256|ARBA:ARBA00023242}; KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553}; KW Reference proteome {ECO:0000313|Proteomes:UP000053283}; KW Repeat {ECO:0000256|ARBA:ARBA00022737}; KW Transcription {ECO:0000256|ARBA:ARBA00023163}; KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}. FT DOMAIN 11..218 FT /note="RHD" FT /evidence="ECO:0000259|PROSITE:PS50254" FT DOMAIN 507..715 FT /note="ANK_REP_REGION" FT /evidence="ECO:0000259|PROSITE:PS50297" FT REPEAT 507..539 FT /note="ANK" FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023" FT REPEAT 546..578 FT /note="ANK" FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023" FT REPEAT 579..602 FT /note="ANK" FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023" FT REPEAT 615..647 FT /note="ANK" FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023" FT REPEAT 649..682 FT /note="ANK" FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023" FT REPEAT 683..715 FT /note="ANK" FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023" FT REGION 391..449 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT REGION 860..888 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COMPBIAS 402..449 FT /note="Basic and acidic residues" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT NON_TER 1 FT /evidence="ECO:0000313|EMBL:KFR08581.1" FT NON_TER 937 FT /evidence="ECO:0000313|EMBL:KFR08581.1" SQ SEQUENCE 937 AA; 102782 MW; F08839677C28D838 CRC64; FIMTFLSFML ADGPYLQIIE QPKQRGFRFR YVCEGPSHGG LPGASSEKNK KSYPQVKICN YVGPAKVIVQ LVTNGKYVHL HAHSLVGKFC EDGVCTVNAG PKDMVVGFAN LGILHVTKKK VFETLETRMI DACKKGYNPG LLVHPELGYL QAEGCGDRQL TEREREIIRQ AAVQQTKEMD LSVVRLMFTA FLPDSNGSFT RKLDPVISDA IYDSKAPNAS NLKIVRMDRT AGCVTGGEEI YLLCDKVQKD DIQIRFYEED ENGGMWEGFG DFSPTDVHRQ FAIVFKTPKY RDVNITKPAS VFVQLRRKSD LETSEPKPFL YYPEIKDKEE VQRKRQKLMP NFSDGYGGGS GAGGGGMYGG GGGGAGSGFS YPSYGYSAFG GMHFHPGTTK SNAGMKHGLS NSTVEHDGKS SDEQSDKWDL KHDVKVETVE RSECRTSGDN EKEEEDASSC KTEVNEADCR WQGDLFLEKA MQLAKRHCNA LFDYAVTGDV KMLLAVQRQL TVVQDDNGDN VLHLAIIHLH TELVKNFLEV MPDLNYNDII NMRNDLYQTP LHLAVITKQA EVVEDLLKAG ADVSLLDRHG NSVLHLAATE GDDKILSLLL KHEKISPMVD LCNGEGLGAI HMVVMANSMS CLKQLIAAGV NVNTQEQKSG RTALHLAVEH ENIPLAACLL LEGDADVDST TYDGTTPLHI AAGRGSTKLA AVLKASGANP HVENFEPLFD LDDVKDDEDD DEGIVPGTTP LDMAANCEVY DILNGKPYES AVASEDLLTQ GHLRDLNESS KMQLYKLLEA PDANKNWSTL AQKLGLGMLN NAFRLSPSPS KTLLDNYEVS GGTVQELIAA LRQMDHTEAI EIIQKALSIS QSPSHQEDDT AKALPSSSPP TFANGETGEL YNSKFQDNES MCDSGVETSF RKLSFTYADS LNSKSSVTLS KMTLGYG //