ID   A0A087WUX3_HUMAN        Unreviewed;       646 AA.
AC   A0A087WUX3;
DT   29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT   29-OCT-2014, sequence version 1.
DT   19-JAN-2022, entry version 30.
DE   SubName: Full=Fibrous sheath-interacting protein 2 {ECO:0000313|Ensembl:ENSP00000478995};
GN   Name=FSIP2 {ECO:0000313|Ensembl:ENSP00000478995};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000478995, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000478995, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=15815621; DOI=10.1038/nature03466;
RA   Hillier L.W., Graves T.A., Fulton R.S., Fulton L.A., Pepin K.H., Minx P.,
RA   Wagner-McPherson C., Layman D., Wylie K., Sekhon M., Becker M.C.,
RA   Fewell G.A., Delehaunty K.D., Miner T.L., Nash W.E., Kremitzki C., Oddy L.,
RA   Du H., Sun H., Bradshaw-Cordum H., Ali J., Carter J., Cordes M., Harris A.,
RA   Isak A., van Brunt A., Nguyen C., Du F., Courtney L., Kalicki J.,
RA   Ozersky P., Abbott S., Armstrong J., Belter E.A., Caruso L., Cedroni M.,
RA   Cotton M., Davidson T., Desai A., Elliott G., Erb T., Fronick C., Gaige T.,
RA   Haakenson W., Haglund K., Holmes A., Harkins R., Kim K., Kruchowski S.S.,
RA   Strong C.M., Grewal N., Goyea E., Hou S., Levy A., Martinka S., Mead K.,
RA   McLellan M.D., Meyer R., Randall-Maher J., Tomlinson C.,
RA   Dauphin-Kohlberg S., Kozlowicz-Reilly A., Shah N., Swearengen-Shahid S.,
RA   Snider J., Strong J.T., Thompson J., Yoakum M., Leonard S., Pearman C.,
RA   Trani L., Radionenko M., Waligorski J.E., Wang C., Rock S.M.,
RA   Tin-Wollam A.-M., Maupin R., Latreille P., Wendl M.C., Yang S.-P., Pohl C.,
RA   Wallis J.W., Spieth J., Bieri T.A., Berkowicz N., Nelson J.O., Osborne J.,
RA   Ding L., Meyer R., Sabo A., Shotland Y., Sinha P., Wohldmann P.E.,
RA   Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Jones T.A., She X.,
RA   Ciccarelli F.D., Izaurralde E., Taylor J., Schmutz J., Myers R.M.,
RA   Cox D.R., Huang X., McPherson J.D., Mardis E.R., Clifton S.W., Warren W.C.,
RA   Chinwalla A.T., Eddy S.R., Marra M.A., Ovcharenko I., Furey T.S.,
RA   Miller W., Eichler E.E., Bork P., Suyama M., Torrents D., Waterston R.H.,
RA   Wilson R.K.;
RT   "Generation and annotation of the DNA sequences of human chromosomes 2 and
RT   4.";
RL   Nature 434:724-731(2005).
RN   [2] {ECO:0000313|Ensembl:ENSP00000478995}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2014) to UniProtKB.
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DR   EMBL; AC007966; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AC008174; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   SMR; A0A087WUX3; -.
DR   PeptideAtlas; A0A087WUX3; -.
DR   Antibodypedia; 51870; 42 antibodies from 10 providers.
DR   Ensembl; ENST00000611759; ENSP00000478995; ENSG00000188738.
DR   UCSC; uc061qll.1; human.
DR   HGNC; HGNC:21675; FSIP2.
DR   OpenTargets; ENSG00000188738; -.
DR   VEuPathDB; HostDB:ENSG00000188738; -.
DR   GeneTree; ENSGT00680000100018; -.
DR   HOGENOM; CLU_013346_0_0_1; -.
DR   ChiTaRS; FSIP2; human.
DR   Proteomes; UP000005640; Chromosome 2.
DR   Bgee; ENSG00000188738; Expressed in testis and 108 other tissues.
DR   ExpressionAtlas; A0A087WUX3; baseline and differential.
DR   InterPro; IPR038891; FSIP2.
DR   InterPro; IPR031554; FSIP2_C.
DR   PANTHER; PTHR47315; PTHR47315; 2.
DR   Pfam; PF15783; FSIP2; 2.
PE   1: Evidence at protein level;
KW   Proteomics identification {ECO:0007829|PeptideAtlas:A0A087WUX3,
KW   ECO:0007829|ProteomicsDB:A0A087WUX3};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640}.
FT   DOMAIN          109..329
FT                   /note="FSIP2"
FT                   /evidence="ECO:0000259|Pfam:PF15783"
FT   DOMAIN          330..635
FT                   /note="FSIP2"
FT                   /evidence="ECO:0000259|Pfam:PF15783"
FT   REGION          57..88
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   646 AA;  72156 MW;  C5008C493B11480F CRC64;
     MVKQLIFSSI PETQIQDRCQ NVSDKQNQAK LYDTAMKLIN SLLKEFSDAQ IKVFRPDKGN
     QFPGGKVSSV PKVPPRYKEP TTDEAPSSIK IKSADKMPPM HKMMRKPSSD KIPSIDKTLV
     NKVVHSSVCN ILNDYGSQDS IWKNINSNGE NLARRLTSAV INEIFQRQVN LIFCDEVSVS
     ACLPLESKDV VKKVQKLAQT ASKECQTSSP YTIILPHKFL ENVISALFSK IFSTISSTKT
     KEPEDNLSTE LNFLQMKLVS AVATEISQDK YMTIQYVETL QSDDDEIIQL VVQSVYNNLL
     PQFGSQEIIQ NCVTSGCKIL SENIVDLVLP KPSHADKLSY NIIEEIAVKF LSKLLSIFPK
     VHKERTKSLE TDMQKITSKV LNSVQEFISK SKIKLVPPTK ESPTVPVADN ATIENIVNSI
     YTSVLKHSGS YTSVFKDLMG KSNVLSDTIG FLMVNAISNS EFQPQVEEEV SNSELVLEAV
     KIMEKVIKII DELKSKEKSS SRKGLTLDAK LLEEVLALFL AKLIRLPSSS SKDEKNLSKT
     ELNKIASQLS KLVTAEISRS SISLIASDPE EHCLNPENTE RIYQVVDSVY SNILQQSGTN
     KEFYYDIKDT NTAFPKKVAS LIIDGVSSFP LIQLTQQFQM LISLES
//