ID A0A087WS06_MOUSE Unreviewed; 231 AA. AC A0A087WS06; DT 29-OCT-2014, integrated into UniProtKB/TrEMBL. DT 14-OCT-2015, sequence version 4. DT 09-DEC-2015, entry version 11. DE SubName: Full=Ankyrin repeat domain-containing protein 27 {ECO:0000313|Ensembl:ENSMUSP00000140848}; DE Flags: Fragment; GN Name=Ankrd27 {ECO:0000313|Ensembl:ENSMUSP00000140848, GN ECO:0000313|MGI:MGI:2444103}; OS Mus musculus (Mouse). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; OC Muroidea; Muridae; Murinae; Mus; Mus. OX NCBI_TaxID=10090 {ECO:0000313|Ensembl:ENSMUSP00000140848, ECO:0000313|Proteomes:UP000000589}; RN [1] {ECO:0000313|Ensembl:ENSMUSP00000140848, ECO:0000313|Proteomes:UP000000589} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000140848, RC ECO:0000313|Proteomes:UP000000589}; RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112; RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., RA She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., RA Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., RA Zhou S., Teague B., Potamousis K., Churas C., Place M., Herschleb J., RA Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., RA Lindblad-Toh K., Eichler E.E., Ponting C.P.; RT "Lineage-specific biology revealed by a finished genome assembly of RT the mouse."; RL PLoS Biol. 7:E1000112-E1000112(2009). RN [2] {ECO:0000313|Ensembl:ENSMUSP00000140848} RP IDENTIFICATION. RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000140848}; RG Ensembl; RL Submitted (SEP-2014) to UniProtKB. CC -!- SIMILARITY: Contains 4 ANK repeats. CC {ECO:0000256|RuleBase:RU003321}. CC -!- CAUTION: The sequence shown here is derived from an Ensembl CC automatic analysis pipeline and should be considered as CC preliminary data. {ECO:0000313|Ensembl:ENSMUSP00000140848}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AC151531; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR Ensembl; ENSMUST00000187807; ENSMUSP00000140848; ENSMUSG00000034867. DR MGI; MGI:2444103; Ankrd27. DR GeneTree; ENSGT00780000121977; -. DR Proteomes; UP000000589; Chromosome 7. DR ExpressionAtlas; A0A087WS06; baseline and differential. DR GO; GO:0005737; C:cytoplasm; ISO:MGI. DR GO; GO:0005769; C:early endosome; ISO:MGI. DR GO; GO:0005770; C:late endosome; ISO:MGI. DR GO; GO:0005764; C:lysosome; ISO:MGI. DR GO; GO:0016020; C:membrane; ISO:MGI. DR GO; GO:0005886; C:plasma membrane; ISO:MGI. DR GO; GO:0097422; C:tubular endosome; ISO:MGI. DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; ISO:MGI. DR GO; GO:0017137; F:Rab GTPase binding; ISO:MGI. DR GO; GO:0045022; P:early endosome to late endosome transport; ISO:MGI. DR GO; GO:0035544; P:negative regulation of SNARE complex assembly; ISO:MGI. DR GO; GO:0043547; P:positive regulation of GTPase activity; ISO:MGI. DR GO; GO:1990126; P:retrograde transport, endosome to plasma membrane; ISO:MGI. DR Gene3D; 1.25.40.20; -; 2. DR InterPro; IPR002110; Ankyrin_rpt. DR InterPro; IPR020683; Ankyrin_rpt-contain_dom. DR Pfam; PF12796; Ank_2; 1. DR PRINTS; PR01415; ANKYRIN. DR SMART; SM00248; ANK; 4. DR SUPFAM; SSF48403; SSF48403; 1. DR PROSITE; PS50297; ANK_REP_REGION; 1. DR PROSITE; PS50088; ANK_REPEAT; 4. PE 1: Evidence at protein level; KW ANK repeat {ECO:0000256|RuleBase:RU003321}; KW Complete proteome {ECO:0000313|Proteomes:UP000000589}; KW Proteomics identification {ECO:0000213|MaxQB:A0A087WS06}; KW Reference proteome {ECO:0000313|Proteomes:UP000000589}. FT DOMAIN 1 231 ANK_REP_REGION. {ECO:0000259|PROSITE: FT PS50297}. FT NON_TER 1 1 {ECO:0000313|Ensembl:ENSMUSP00000140848}. FT NON_TER 231 231 {ECO:0000313|Ensembl:ENSMUSP00000140848}. SQ SEQUENCE 231 AA; 25321 MW; E674A07AB1D1E269 CRC64; XFQSVTLLLL HYKASTEVQD NNGNTPLHLA CTYGQEDCVK ALVYYDVQAC RLDIGNEKGD TALHIAARWG YEGIIETLLQ NGAPTAVQNR LKETPLKCAL NSKVEKLLRA VADGDLEMVR YLLEWTEDDL DDVEDAISTV DLEFCHPLCQ CPKCAPAQKL ARISANGLSV NVTNQDGFSP LHMAALHGRT DLVPLLLKHG AYSGARNTSQ AVPLHLACQQ GHFQVAKCLL D //