ID A0A087WRE9_MOUSE Unreviewed; 264 AA. AC A0A087WRE9; DT 29-OCT-2014, integrated into UniProtKB/TrEMBL. DT 29-OCT-2014, sequence version 1. DT 07-NOV-2018, entry version 25. DE SubName: Full=E3 ubiquitin-protein ligase RING2 {ECO:0000313|Ensembl:ENSMUSP00000140594}; GN Name=Rnf2 {ECO:0000313|Ensembl:ENSMUSP00000140594, GN ECO:0000313|MGI:MGI:1101759}; OS Mus musculus (Mouse). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; OC Muroidea; Muridae; Murinae; Mus; Mus. OX NCBI_TaxID=10090 {ECO:0000313|Ensembl:ENSMUSP00000140594, ECO:0000313|Proteomes:UP000000589}; RN [1] {ECO:0000313|Ensembl:ENSMUSP00000140594, ECO:0000313|Proteomes:UP000000589} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000140594, RC ECO:0000313|Proteomes:UP000000589}; RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112; RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., RA She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., RA Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., RA Zhou S., Teague B., Potamousis K., Churas C., Place M., Herschleb J., RA Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., RA Lindblad-Toh K., Eichler E.E., Ponting C.P.; RT "Lineage-specific biology revealed by a finished genome assembly of RT the mouse."; RL PLoS Biol. 7:E1000112-E1000112(2009). RN [2] {ECO:0000213|PubMed:21183079} RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]. RX PubMed=21183079; DOI=10.1016/j.cell.2010.12.001; RA Huttlin E.L., Jedrychowski M.P., Elias J.E., Goswami T., Rad R., RA Beausoleil S.A., Villen J., Haas W., Sowa M.E., Gygi S.P.; RT "A tissue-specific atlas of mouse protein phosphorylation and RT expression."; RL Cell 143:1174-1189(2010). RN [3] {ECO:0000313|Ensembl:ENSMUSP00000140594} RP IDENTIFICATION. RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000140594}; RG Ensembl; RL Submitted (SEP-2014) to UniProtKB. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AC115060; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; AC165946; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR SMR; A0A087WRE9; -. DR Ensembl; ENSMUST00000186415; ENSMUSP00000140594; ENSMUSG00000026484. DR MGI; MGI:1101759; Rnf2. DR eggNOG; KOG0311; Eukaryota. DR eggNOG; ENOG410XQ5G; LUCA. DR GeneTree; ENSGT00390000016977; -. DR ChiTaRS; Rnf2; mouse. DR Proteomes; UP000000589; Chromosome 1. DR Bgee; ENSMUSG00000026484; Expressed in 298 organ(s), highest expression level in pineal body. DR ExpressionAtlas; A0A087WRE9; baseline and differential. DR Gene3D; 3.30.40.10; -; 1. DR InterPro; IPR039642; E3_Ub_ligase/polycomb_RING. DR InterPro; IPR032443; RAWUL. DR InterPro; IPR001841; Znf_RING. DR InterPro; IPR013083; Znf_RING/FYVE/PHD. DR InterPro; IPR017907; Znf_RING_CS. DR PANTHER; PTHR10825; PTHR10825; 2. DR Pfam; PF16207; RAWUL; 1. DR SMART; SM00184; RING; 1. DR PROSITE; PS00518; ZF_RING_1; 1. DR PROSITE; PS50089; ZF_RING_2; 1. PE 1: Evidence at protein level; KW Complete proteome {ECO:0000313|Proteomes:UP000000589}; KW Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00175}; KW Proteomics identification {ECO:0000213|EPD:A0A087WRE9, KW ECO:0000213|MaxQB:A0A087WRE9, ECO:0000213|PeptideAtlas:A0A087WRE9}; KW Reference proteome {ECO:0000313|Proteomes:UP000000589}; KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00175}; KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00175}. FT DOMAIN 51 76 RING-type. {ECO:0000259|PROSITE:PS50089}. SQ SEQUENCE 264 AA; 29226 MW; 2772168F333B16C8 CRC64; MSQAVQTNGT QPLSKTWELS LYELQRTPQE AITDGLEIVV SPRSLHSELM CPICLDMLKN TMTTKECLHR FCADCIITAL RSGLQRGKKQ QIENGSGAED NGDSSHCSNA STHSNQEAGP SNKRTKTSDD SGLELDNNNA AVAIDPVMDG ASEIELVFRP HPTLMEKDDS AQTRYIKTSG NATVDHLSKY LAVRLALEEL RSKGESNQMN LDTASEKQYT IYIATASGQF TVLNGSFSLE LVSEKYWKVN KPMELYYAPT KEHK //