ID A0A087WQ20_MOUSE Unreviewed; 128 AA. AC A0A087WQ20; DT 29-OCT-2014, integrated into UniProtKB/TrEMBL. DT 29-OCT-2014, sequence version 1. DT 22-FEB-2023, entry version 36. DE SubName: Full=Transformed mouse 3T3 cell double minute 4 {ECO:0000313|Ensembl:ENSMUSP00000140006.2}; GN Name=Mdm4 {ECO:0000313|Ensembl:ENSMUSP00000140006.2, GN ECO:0000313|MGI:MGI:107934}; OS Mus musculus (Mouse). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; OC Murinae; Mus; Mus. OX NCBI_TaxID=10090 {ECO:0000313|Ensembl:ENSMUSP00000140006.2, ECO:0000313|Proteomes:UP000000589}; RN [1] {ECO:0000313|Ensembl:ENSMUSP00000140006.2, ECO:0000313|Proteomes:UP000000589} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000140006.2, RC ECO:0000313|Proteomes:UP000000589}; RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112; RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., RA Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y., RA Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S., RA Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R., RA Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K., RA Eichler E.E., Ponting C.P.; RT "Lineage-specific biology revealed by a finished genome assembly of the RT mouse."; RL PLoS Biol. 7:E1000112-E1000112(2009). RN [2] {ECO:0000313|Ensembl:ENSMUSP00000140006.2} RP IDENTIFICATION. RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000140006.2}; RG Ensembl; RL Submitted (OCT-2022) to UniProtKB. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR AlphaFoldDB; A0A087WQ20; -. DR SMR; A0A087WQ20; -. DR ProteomicsDB; 316865; -. DR Antibodypedia; 20673; 766 antibodies from 38 providers. DR Ensembl; ENSMUST00000191212.7; ENSMUSP00000140006.2; ENSMUSG00000054387.14. DR AGR; MGI:107934; -. DR MGI; MGI:107934; Mdm4. DR VEuPathDB; HostDB:ENSMUSG00000054387; -. DR GeneTree; ENSGT00530000063539; -. DR ChiTaRS; Mdm4; mouse. DR Proteomes; UP000000589; Chromosome 1. DR Bgee; ENSMUSG00000054387; Expressed in secondary oocyte and 243 other tissues. DR ExpressionAtlas; A0A087WQ20; baseline and differential. DR GO; GO:0005634; C:nucleus; IEA:InterPro. DR GO; GO:0043066; P:negative regulation of apoptotic process; IEA:InterPro. DR GO; GO:0051726; P:regulation of cell cycle; IEA:InterPro. DR GO; GO:0051239; P:regulation of multicellular organismal process; IEA:UniProt. DR CDD; cd17673; MDM4; 1. DR Gene3D; 1.10.245.10; SWIB/MDM2 domain; 1. DR InterPro; IPR016495; p53_neg-reg_MDM_2/4. DR InterPro; IPR036885; SWIB_MDM2_dom_sf. DR InterPro; IPR003121; SWIB_MDM2_domain. DR PANTHER; PTHR46858; OS05G0521000 PROTEIN; 1. DR PANTHER; PTHR46858:SF12; PROTEIN MDM4; 1. DR Pfam; PF02201; SWIB; 1. DR PIRSF; PIRSF006748; p53_MDM_2/4; 1. DR SUPFAM; SSF47592; SWIB/MDM2 domain; 1. DR PROSITE; PS51925; SWIB_MDM2; 1. PE 1: Evidence at protein level; KW Proteomics identification {ECO:0007829|MaxQB:A0A087WQ20, KW ECO:0007829|ProteomicsDB:A0A087WQ20}; KW Reference proteome {ECO:0000313|Proteomes:UP000000589}. FT DOMAIN 23..109 FT /note="DM2" FT /evidence="ECO:0000259|PROSITE:PS51925" SQ SEQUENCE 128 AA; 14271 MW; 5D7CF148D782818D CRC64; MTSHSTSAQC SASDSACRIS SEQISQQVRP KLQLLKILHA AGAQGEVFTM KEVMHYLGQY IMVKQLYDQQ EQHMVYCGGD LLGDLLGCQS FSVKDPSPLY DMLRKNLVTS ASINTARCNR ILQSQKKN //